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The charade—

My whole may be a mother, not a dad,
So former may, or latter;
But twist my tail, and I become as mad
As any hatter!

Behead me, and behold I am a man,
Who never was called mister;
Cut off my tail, and instantly I can
Become a sister!

is solved by Madam (ma, dam, mad, Adam, Ada).

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