SECT. XIX.—ON GANGRENE AND SPHACELUS.
When the inflammation is neither resolved nor converted into pus, it often passes into gangrene and sphacelus, of which we shall now treat. Wherefore, we give the name of gangrene to mortifications arising from the violence of the inflammation, when they are not yet formed but forming; and if such a state is not speedily cured, the affected part readily dies, and the disease seizing upon the surrounding parts, kills the person. But when the parts thus affected become totally insensible, the affection is no longer called gangrene, but sphacelus. This affection happens also to the bones when the flesh that surrounds them engendering noxious humours impregnates the bones therewith, and causes them to putrefy. When, therefore, the part is completely mortified, it must be speedily cut away, where it joins the sound part. Gangrene is to be cured by evacuating as much as possible of the blood in the affected part; and we may either procure the discharge of the corrupted blood by opening a vein, when the vein of the part is large, or we may divide the whole skin by many and deep incisions, so that the blood may be permitted to escape; and we may apply some of the medicines suitable to mortifications. These are, the flour of tares, or of darnels, or of beans with oxymel. When wishing to apply stronger ones we may add salts, or use the trochisk of Andron, or the like. Old walnuts are good applications for gangrene. The nettle also cleans them, and the juice of spurge, when applied in season and in proper quantity. The decoction of bitter lupines, poured on the part, is also beneficial. Some after the incision, for the sake of security, apply the cautery, in which cases we must use salt with leeks: afterwards, in order to remove the eschar, we may apply a cataplasm of bread, or of barley, or of wheaten flour boiled in water and oil; or the dry cephalic powder with honey, and the tetrapharmacon; and that called the Macedonian may be used. The eschars may be properly removed by bread triturated with parsley, or basil, or by iris, panacea, or birthwort, or by the sweet-flag with honey, or by frankincense. And the medicine of Machærion takes away the eschars in a proper manner, and the iris spread upon pledgets with honey; but in soft bodies the flour of tares, with honey, is sufficient.
From the works of Oribasius, for gangrene. Of scraped verdigris, of vermilion, of stone alum, equal parts; triturate in water and anoint. The flour of darnel, with radish and salts, and sometimes with vinegar, will, when applied as a cataplasm, be proper for the scarified parts; also dried grapes deprived of their stones with the bark, and with salts and oxymel; the inner parts of walnuts, and myrtle leaves boiled in wine and triturated with honey. Radish, with vinegar, breaks the eschars even to the bone.
Commentary. See the authors referred to in [the 17th Section].
Paulus copies freely from Oribasius (Synops. vii, 27.) Upon comparing Oribasius with our author we have ventured to give an interpretation of the last sentence not justified by the text as it now stands, and at variance with the translation of Cornarius. Oribasius does not say that the flour of darnel will scarify the parts (how could he?) but that it will be a proper application after the parts are scarified.
Galen (ad Glauc. and Comment. in Hippocr. App. vii. 50,) is the great ancient authority on mortification, and from him Oribasius, Aëtius, Paulus, and all the subsequent writers on this subject have copied. He lays it down as the great rule of treatment, to evacuate the blood which is impacted in the part and prevents the diastole of the arteries. To accomplish this end he directs free incisions to be made, after which the actual cautery is to be applied, at the line of separation between the sound and diseased parts.
Celsus is a strong advocate for this practice, which has been revived lately and is much used in France. (See Encyclopédie Méthiodique, art. Gangrène, and Cross’s Sketches of the Medical Schools in Paris.) He states, however, that when the disease goes on spreading, amputation of the mortified limb is the “auxilium unicum.” At the commencement he approves of venesection, if the strength permit, and of a restricted diet; and, afterwards, astringent food and drink are to be given. He also recommends, for gangrene, applications containing arsenic, quicklime, chalcitis, and the like (v, 22.)
The practice of the Arabians is little or nothing different from that of the Greeks. Avicenna at the commencement approves of Armenian bole and terra sigillata with vinegar; but if these have not the effect he directs us to empty the part by scarifications, leeches, or opening the veins which lead to it. He then recommends us to apply the flour of beans and the other remedies mentioned by the Greeks. When the disease proceeds, free incisions and the actual cautery must be had recourse to. Alsaharavius recommends us to bleed at first, if the strength permit; then to use powerful caustics and escharotics such as arsenic, quicklime, and sublimed quicksilver; or if these do not succeed, the actual cautery. He approves of early incisions, and of amputation, if the mortification spread. He describes a species of gangrene which seizes the hand and spreads upwards; and relates a case of it in which he refused to amputate for fear of hemorrhage. The same case is related by Albucasis, which certainly amounts to a strong presumptive proof that Alsaharavius was the same person as Albucasis. Rhases inculcates in the strongest terms that when an inflammation threatens to terminate in mortification, it is to be treated by scarifications, stimulant applications, and the cautery.
The earlier modern surgeons followed the ancient practice of applying the cautery in cases of gangrene.