SECT. VIII.—ON THE ANTIDOTES CALLED HIERÆ.
The hiera of Antiochus. Of germander, of agaric, of the medullary part of colocynth, of cassidony, of each dr. x; of opoponax, of sagapen, of stone-parsley, of the species of birthwort called clematis, of white pepper, of each dr. v; of cinnamon, of spikenard, of troglodytic myrrh, of the leaves of saffron, of each dr. iv; of honey, q. s.—Another hiera. Of the medullary part of colocynth, dr. xx; of baked squills, of agaric, of ammoniac perfume, of the bark of black hellebore, of scammony, of St. John’s wort, of each dr. iij; of dodder of thyme, of dried polypody, of bdellium, of aloes, of germander, of horehound, of cassia, of each dr. viij; of troglodytic myrrh, of opoponax, of sagapen, of stone-parsley, of the common long, and white pepper, of cinnamon, of saffron, of castor, of the long birthwort, of each dr. iv; of honey, q. s.
The hiera of Justus. Of dodder of thyme, dr. xij; of horehound, of cassidony, of germander, of black hellebore, of scammony, of agaric, of long pepper, of baked squills, of each dr. xvj; of euphorbium, of the medullary part of colocynth, of aloes, of saffron, of gentian, of stone-parsley, of ammoniac perfume, of sagapen, of each dr. viij; of opoponax, of poley, of cinnamon, of myrrh, of spikenard, of the flower of the rush, of pennyroyal, of each dr. iv; of long and of round birthwort, of each dr. ij; of honey, q. s. The dose is two, three, or four scr., with honeyed water and salts.
The hiera of Galen. Of germander, of long pepper, of white pepper, of cassidony, of black hellebore, of scammony, of spikenard, of baked squills (and some of dodder of thyme), of each dr. xvj; of myrrh, of saffron, of ammoniac perfume, of euphorbium, of each dr. viij. Mix with honey.
The hiera of Ruffus. Of sicyonia, or the medullary part of colocynth, dr. viij; of germander, dr. x; of sagapen, dr. viij; of stone-parsley, dr. v; of round birthwort, dr. v; of white pepper, dr. v; of cinnamon, dr. iv; or of cassia, dr. viij; of base horehound, of saffron, of poley, of myrrh, of each dr. iv; of honey, q. s.
The hiera of Archigenes. Of horehound, of agaric, of germander, of the medullary part of colocynth, of cassidony, of each dr. x; of opoponax, of sagapen, of stone-parsley, of round birthwort, of white pepper, of each dr. v; of cinnamon, of spikenard, of myrrh, of the cassia leaf (malabathrum), of saffron, of each dr. iv; pound the dry things together, and strain. The opoponax, sagapen, and myrrh, being bruised, are to be put into a mortar to macerate with honeyed water for one night; then triturate and add the dry things; then mixing them with the finest honey lay them up in a glass or leaden vessel. This is the common method with all the hieræ. The full dose of them is dr. iv. Add to it also of salts, dr. j; of honey, two cyathi; of water, q. s. If we wish to make those compositions of this class which have not scammony more purgative, we must add to each of them an obolus of it.
Commentary. The hieræ, for the most part, consist of drastic purgatives, combined with aromatics. There is a great variety of these compositions described in the works of the ancient winters on pharmacy. Galen makes mention of an aloetic hiera, which was much used by the celebrated Archigenes. The following is his prescription for it: “R. Aloes, dr. c; cinnamomi, nardi, xylobalsami, mastichæ chiæ, asari, croci, ā ā dr. vj.” Galen remarks, however, that the proportion of aloes is too great, and recommends us to substitute xc or lxxx dr. instead of the quantity directed. (De comp. Med. acc. loc.) Mesue describes the composition of 6 hieræ, Haly Abbas of 5, and Serapion of a much greater number. But for variety, Myrepsus surpasses all the other authorities. He describes the composition of 30 hieræ. The following is his receipt for the Hiera Picra Galeni: “℞. Aloes flavæ, dr. xivss.; cinnamomi, croci, costi, floris junci odorati, xylobalsami, cassiæ fistulæ puræ, mastiches, asari, rosarum, amomi, absinthii, ā ā dr. j; Tere subigendo cum mellis Attici q. s.” Moses Charras’s receipt for it is very little different. (Royal Pharm. i, 20.)