IMPORTANT CAUTION.

Owing to the success obtained by our preparations of Coca for many years, imitators and counterfeiters have dared to apply to their own valueless productions the observations made with our special products. These occurrences, often repeated, have given rise to protests from many physicians, among others Dr. W. Oliver Moore, Sir Morell Mackenzie, Dr. Ch. Fauvel.

To the Editor of the New York Medical Journal:

Sir: In your issue of January 3, 1885, page 19, in a report of a paper read before the New York Medical Society, on "The Physiological and Therapeutical Effects of the Coca Leaf and its Alkaloid," occurs the following: "For over twenty years Dr. Fauvel has used it, both internally in the form of Vin Mariani, and also by local applications to the pharynx and larynx in spray or by brush, in the form of a fluid extract, or, more recently, of a concentrated non-alcoholic preparation more of the nature of a cordial (prepared by Mariani & Co.)."

Several manufacturers of Coca preparations have taken occasion to quote from this paper, each in turn substituting the name of his own production instead of the one mentioned in the original.

As the preparations of Coca mentioned in my paper were personally tested and found to be the best of a large number experimented with, I wish to call attention to these misquotations and substitutions.

Very truly,
W. Oliver Moore, M.D.

⁂ We have taken the trouble to compare the report of Dr. Moore's remarks with the little book on Coca prepared by M. Mariani, and with the circulars issued by a number of manufacturers of Coca preparations; and we certainly think that some of these manufacturers have taken an unwarrantable liberty in appropriating work that evidently cost M. Mariani a good deal of time and no little outlay of money.—Editor N. Y. Medical Journal.

New York Medical Journal, October 24, 1885.

"In another column we publish a letter from Dr. W. Oliver Moore, calling attention to an injustice that certain competing pharmacists have practiced toward Messrs. Mariani & Co., in 'pirating' published records of the successful use of the Mariani preparations of Coca, and at the same time craftily making these records appear to apply to their own preparations. It is very much to be regretted that a house that has been so punctilious in avoiding even the semblance of any offense against the courtesy of trade should have been treated in this shabby way by some rival manufacturers."

31 Rue Guénégaud, Paris, Dec. 8, 1887.

To the Editor of the New York Medical Journal:

Sir—Will you kindly have it announced in your journal, in justice to myself before the medical profession, that the various notices appearing in journals and circulars quoting my name in connection with Coca are entirely false and in every respect a prevarication? The only preparation of Coca employed by me with undoubted and uniform success has been the so well-known Vin Mariani, which, since 1865, I have had occasion to prescribe daily in my clinique, as well as in private practice. My opinion of this valuable medicament has, during many years, been frequently made known for the benefit of the profession in various writings, and it is but just to this worthy preparation that it receive all the honor due it. I thank you for compliance with my request.

Ch. Fauvel, M.D.

Continued compliment is paid M. Mariani for the maintained high standard and excellence of his preparations, by the numerous honorable mentions and indorsements by the members of the medical profession and those who have occasion to use his Coca preparations; latterly through the following awards:

Gold Medal and Silver Medal from the Académie Nationale de France; Gold Medal and a Grand Diploma of Honor from the Wine Exhibit of Bordeaux, France; Gold Medal and a Diploma of Honor at the Hygienic Exhibit at Amsterdam, Holland, and a Gold Medal and Diploma at Leamington, England, the jury surnaming his Vin Mariani, "Wine for Athletes."

N. B.—Professional bicyclists and athletes, after careful trials of ours and preparations of others, among which the Cafeine. Theobromine, Kola, pseudo-Cafeine or Kolamine (Knebel), Maté, etc., invariably give the preference to our Coca preparation. Messrs. Dubois, Lucas, Vigneaux, Echalié, André Henry, Imans, Buffel, and many others have attested to the vast superiority of Coca Mariani over all other tonics (dynamogéniques).

We request those physicians, who kindly place confidence in our preparations, to prescribe them under the name of Mariani, and to insist that their prescriptions be scrupulously executed.

PLATE I.

TRANSVERSE SECTION OF A YOUNG BRANCH; PRIMARY FORMATIONS.

(See Plate III., Figure 3.)

PLATE II.

Fig. 1—TRANSVERSE SECTION OF AN AGED STEM; SECONDARY FORMATIONS.

Fig. 2—LONGITUDINAL SECTION OF SAME STEM.

Bark formed of a corky and pulpy cortical of a secondary origin. The primary bark exfoliates itself at a very early stage.

The pulp contains some oxaliferous cellules and some grains of starch.

The wood contains some veins and a considerable quantity of fibres with thick and dotted partitions. The marrow remains always pulpy and with lignified cellules.

PLATE III.

Fig. 1—TRANSVERSE SECTION OF A PRIMARY ROOT.

Fig. 2—TRANSVERSE SECTION OF A ROOT; SECONDARY FORMATIONS.

Fig. 3—SCHEMATIC SECTION OF A YOUNG BRANCH.

Fig. 4—GRAINS OF STARCH OF THE SEED.

(Maximum dimensions: 22 to 24 p. × 15 to 18 p.)

PLATE IV.

Fig. 1—FOLIATION. TRANSVERSE SECTION OF A LEAF NOT YET UNROLLED, SHOWING THE TWO LONGITUDINAL JUTTINGS WHICH FORM THE FALSE NERVURES OF THE COCA LEAF.

Fig. 2—TRANSVERSE SECTION OF ONE OF THE JUTTINGS.

Fig. 3—LOWER EPIDERMIS OF THE LEAF AT THE FALSE NERVURE F. n., WHICH IS FORMED OF LENGTHENED CELLULES WITHOUT STOMATUM S., STOMATUM P., EPIDERMIC PAPILLOUS CELLULES.

Fig. 4—TRANSVERSE SECTION OF A LEAF ENTIRELY DEVELOPED.

Fig. 5—SCHEMATIC SECTION OF A PETIOL NEAR THE BASE.

Fig. 6—EXTREMITY OF A BRANCH SHOWING THE STIPULES OF THE LEAVES.

Fig. 7—TWO STIPULES CONNECTED, SEEN FROM THE BRANCHED SURFACE.

PLATE V.

Fig. 1—RIPE SEED; THE THREE STYLES AND THE STAMENS ARE STILL ADHERENT.

Fig. 2—LONGITUDINAL SECTION OF SAME.

Fig. 3—SCHEMATIC SECTION OF THE HALF-DEVELOPED SEED.

Fig. 4—TRANSVERSE SCHEMATIC SECTION OF A COTYLEDON.

Fig. 5—FLORAL BUD.

Fig. 6—AN EXPANDED FLOWER.

Fig. 7—THE SAME, SEEN FROM UNDERNEATH.

Fig. 8—TWO PETALS, ONE SEEN FROM UNDERNEATH, THE OTHER SEEN SIDEWAYS AND SHOWING THE APPENDIX WHICH FORMS THE CROWN.

Fig. 9—THE ATTACHED 10 STAMENS; THE EPIPETALS ARE LARGER THAN THE EPISEPALS.

Fig. 10—AN ANTHER AND THREAD OF STAMEN.

Fig. 11—POLLEN SEEDS.

(Dimensions: 35 p. × 28 p.)

Fig. 12—STYLE AND STIGMATE.

Fig. 13—FLORAL DIAGRAM.

The floral formula is: [5 S] + 5 P + [10 E] - [3 C].

We are justified in saying: Never has anything been so highly recommended and every trial proves its excellence.

"Mariani Bottle," showing Shape and Label.
Size of Regular Bottle, half litre (about 17 ounces).

"Mariani Bottle," showing Outside Wrapper.
Never sold in bulk—to guard against substitution.

VIN MARIANI

Nourishes = Fortifies

Refreshes

Aids Digestion = Strengthens the System.

Unequaled as a tonic-stimulant for fatigued or overworked Body and Brain.

Prevents Malaria, Influenza and Wasting Diseases.

We cannot aim to gain support for our preparation through cheapness; we give a uniform, effective and honest article, and respectfully ask personal testing of Vin Mariani strictly on its own merits. Thus the medical profession can judge whether Vin Mariani is deserving of the unequaled reputation it has earned throughout the world during more than 30 years.

Inferior, so-called Coca preparations (variable solutions of Cocaine and cheap wines), which have been proven worthless, even harmful in effect, bring into discredit and destroy confidence in a valuable drug.

We therefore particularly caution to specify always "VIN MARIANI," thus we can guarantee invariable satisfaction to physician and patient.