CONTENTS

Historical Introduction—Spontaneous Generation—Causation of Disease—Putrefaction and Fermentation—Study of Forms—Chronological Table[17]
[CHAPTER I.]
Position of Bacteria—Relationships to Algæ—Yeasts—Molds—Protozoa[37]
[PART I.]
MORPHOLOGY.
[CHAPTER II.]
Cell Structures—Cell Wall—Protoplasm—Plasmolysis—Plasmoptysis—Nucleus—Vacuoles—Capsules—Metachromatic Granules—Flagella—Spores[41]
[CHAPTER III.]
Cell Forms—Coccus—Bacillus—Spirillum—Involution Forms[52]
[CHAPTER IV.]
Cell Groupings[55]
[CHAPTER V.]
Classification—Migula’s—Society of American Bacteriologists’—Key to the Latter[59]
[PART II.]
PHYSIOLOGY.
[CHAPTER VI.]
Occurrence—General Conditions for Growth—Moisture—Temperature—Light—Oxygen—Osmotic Pressure—Electricity—X-rays and Radium Emanations—Pressure—Mechanical Vibration[71]
[CHAPTER VII.]
Chemical Environment—Reaction of Medium—Chemical Composition[81]
[CHAPTER VIII.]
Chemical Environment (Continued)—General Food Relationships—Metabolism of Elements[86]
[CHAPTER IX.]
Physiological Activities—Fermentation of Carbohydrates—Splitting of Fats[93]
[CHAPTER X.]
Physiological Activities (Continued)—Putrefaction of Proteins—Cycles of Nitrogen, Carbon, Sulphur, Phosphorus[102]
[CHAPTER XI.]
Physiological Activities (Continued)—Production of Acids, Gases, Esters, Alcohols, Aldehydes, Aromatic Compounds—Phosphorescence—Chromogenesis—Reduction—Oxidation—Production of Heat—Absorption of Free Nitrogen—Nitrogen Nutrition of Green Plants[110]
[CHAPTER XII.]
Physiological Activities (Continued)—Production of Enzymes—Discussion on Enzymes—Toxins—Causation of Disease[121]
[CHAPTER XIII.]
Disinfection—Sterilization—Disinfectants—Physical Agents—Pasteurization[130]
[CHAPTER XIV.]
Disinfection and Sterilization (Continued)—Chemical Agents—Anilin Dyes[156]
[CHAPTER XV.]
Disinfection and Sterilization (Continued)—Choice of Agent—Standardization of Disinfectants—Phenol Coefficient—Practical Sterilization and Disinfection[164]
[PART III.]
THE STUDY OF BACTERIA.
[CHAPTER XVI.]
Culture Media—Broth, Milk, Gelatin, Agar, Potatoes, Blood Serum—Standardization of Media—H-ion Concentration Method—Synthetic Media[171]
[CHAPTER XVII.]
Methods of Using Culture Media—Culture Tubes—Plates—Anaërobic Cultures—Vignal Tubes—Fermentation Tubes—Deep Culture Tubes—Novy Jars—Inoculation of Culture Media[184]
[CHAPTER XVIII.]
Isolation of Bacteria in Pure Culture—Dilution—Plating—Streaking—Barber Apparatus—Aids in Isolation—Heat—Selective Antiseptics—Selective Food—-Indicators—Animal Inoculation[194]
[CHAPTER XIX.]
Study of the Morphology of Bacteria—Bacteriological Microscope—Hanging Drop Slides—Staining—Gram’s Method—Spores—Acid-fast Bacilli—Capsules—Flagella—Metachromatic Granules[200]
[CHAPTER XX.]
Study of the Physiology of Bacteria—Temperature—Incubators—Thermal Death Point—Oxygen Relationships—Study of Physiological Activities—Appearance of Growth on Culture Media—Appearance of Molds on Plate Cultures[213]
[CHAPTER XXI.]
Animal Inoculation—Material for Bacteriological Examination[227]
[PART IV.]
GENERAL PATHOGENIC BACTERIOLOGY.
[CHAPTER XXII.]
Introduction—Infection—Acute Infection—Chronic Infection—Specific—Non-specific—Koch’s Postulates—Virulence—Susceptibility[231]
[CHAPTER XXIII.]
Pathogenic Bacteria Outside the Body—As Saprophytes—As Facultative Saprophytes—Latent—Carriers—Universal Carriers—Accidental Carriers—Necessary Intermediate Hosts[237]
[CHAPTER XXIV.]
Channels of Infection—Skin—Mucosæ—Respiratory Tract—Alimentary Tract—Mechanism of Entrance of Organisms—Dissemination in the Body—Paths of Elimination—Specificity of Location[243]
[CHAPTER XXV.]
Immunity—Natural—Artificial—Active—Passive—Production of Immunity—Vaccine—Antiserum—Practical Applications of Immunity Reactions[250]
[CHAPTER XXVI.]
Theories of Immunity—Pasteur—Chauveau—Baumgärtner—Metchnikoff—Ehrlich—Principles of Ehrlich’s Theory[256]
[CHAPTER XXVII.]
Ehrlich’s Theory (Continued)—Receptors of the First Order—Antitoxin—Antienzyme—Preparation of Antitoxins—Units[261]
[CHAPTER XXVIII.]
Ehrlich’s Theory (Continued)—Receptors of the Second Order—Agglutinins—Agglutination Reaction—Precipitins—Precipitin Test[265]
[CHAPTER XXIX.]
Ehrlich’s Theory (Continued)—Receptors of the Third Order—Cytolysins—Amboceptor—Complement—Anti-amboceptors—Antisnake Venoms—Failure of Cytolytic Serums in Practice—Complement-fixation Test[271]
[CHAPTER XXX.]
Phagocytosis—Opsonins—Opsonic Index—Bacterial Vaccines—Preparation of—Use of—Lipovaccines—Aggressins[280]
[CHAPTER XXXI.]
Anaphylaxis—Author’s Theory—Tuberculin Test—Table of Antigens and Antibodies—Summary of Immunity as Applied to Protection from Disease[289]