AMYLOID DEGENERATION OF THE SPLEEN.
Amyloid: horse: with exhausting diseases. Waxy secretion staining mahogany brown with iodine. Gangrene: Swine. Tubercle and glander nodules.
This has been occasionally detected in the spleen of the horse. It is usually connected with longstanding suppuration especially of bones, with advanced tuberculosis or other exhausting disease. The organ is usually greatly enlarged and the affected parts are firm, resistant and swollen. On section it has not the soft friable or pulpy appearance of the spleen, but an uniform waxy looking consistency, grayish or sometimes stained with blood. On the application of a solution of iodine and iodide of potassium the healthy splenic tissue is colored yellow, while the amyloid portion becomes of a deep mahogany brown.