NOTES
[1] "It matters little how vague and false hypotheses may appear at first: experiment will gradually reduce and correct them, and all that is required, is industry to elaborate the proof, and impartiality to secure it from distortion."—Sewell "On the Cultivation of the Intellect."
[2] It is stated by Mr. Crosse, of Norwich, that vaccination was adopted in Denmark, and made compulsory in 1800. After the year 1808 Small Pox no longer existed there, and was a thing totally unknown; whereas during the twelve years preceding the introduction of the preventive disease, 5,500 persons died of the Small Pox in Copenhagen alone.—Dr. Watson's Lectures.
Dr. Blick, an intelligent Danish physician, corroborated the above statement to Dr. Watson himself in the year 1838.
[3] Philosophy of Life, Lecture 6, translated by the Rev. A. J. W. Morrison, M.A.
[4] The following I quote from Dr. Fuller on Small Pox and Measles:—
"To this purpose some (and particularly Kircherus) are of opinion that animalcules have been the causes of malignant and pestilential fevers in epidemic times, which differ in essence and symptoms, according to the nature and venoms of those creatures.
"Thus the atmosphere and air is filled both from above and beneath with innumerable millions of millions of species or corpuscles, aporrhœas, steams, vapours, fumes, dust, little insects, &c. all which make it such a wonderful chaotic compost of things that contains the seeds of good and evil to man as surpasseth the understanding (as I suppose) of even the highest order of archangels."
[5] I learn from an undoubted authority that the cow when "slack of health" eats with avidity the "field parsley;" the sheep under similar circumstances seeks the ivy, and the goat the plantain.
From an equally good source I have the following: that rabbits and hares, when they are what is commonly called pot-gutted, seek the green broom, though at a distance of twenty miles.
[6] "My settled opinion is, that in regard every effect is necessarily such as its cause; it must needs be that every sort of venomous fevers is produced by its proper and peculiar species of virus.
"And that the manner and symptoms of every such fever is not so much from the particular constitution of the sick; as from the different nature and genius of their specific venom which caused them.
"And I conceive that venomous febrile matters differ not in degree of intenseness only, but in essence and toto genere also; and that venomous fevers are for the most part contagious."—Thomas Fuller, M. D. 1730. "Another important class of organic poisons are those which when introduced in almost inappreciable quantities into the system, seem to increase in quantity; and which when communicated in the same inappreciable quantity from the individual poisoned to one who is healthy, excite the same series of febrile phenomena and local inflammation, and the same increase in the quantity of the poisonous agent."—Med. Chir. Review.
"This unseen influence working in the body, presents very striking analogies to the modes of operation of different poisons."—Dr. Ormerod on Continued Fever.
[7] I am aware that the vesicle does not here strictly bear the relation to the original germ, supposing one active particle alone to be sufficient for its production, that the egg does to the bird, for in the former case multitudes of active particles may have been generated from one. I have, therefore, merely used this expression to signify an aggregation of vital forces, such as may be imagined to exist in the bird.
[8] "At an early period the form of the ovisacs is usually elliptical, and their size extremely minute,—their long diameter measuring in the ox no more than 1/562 of an inch, so that a cubic inch would contain nearly two hundred millions of them. They are at this time quite distinct from the stroma of the ovarium; this forms a cavity in which they are loosely embedded."
[9] Coleridge, p. 56.
[10] "All vegetables," says Sharon Turner, "from that pettiness which escapes our natural sight, to that magnitude which we feel to be gigantic, have these properties in common with all animals—organization; an interior power of progressive growth, a principle of life, with many phenomena that resemble irritability, excitability, and susceptibility, and a self-reproductive and multiplying faculty."—Sharon Turner's Sacred History.
[11] "Plants highly sensitive to light are those of the leguminous, or Pea kind. They always close up in the evening and clasp their two upper surfaces together, presenting only their backs to the air. Plants of pinnated leaves, as the Tansy, are more sensible than these to the effects of light. They fold up when light is too strong, as in Robinia; it produces the same effect as want of light. Its leaves close up, apparently, because they are receiving too much. So they do if a hot iron be brought near them. They contract as if to avoid the heat. Sensitive plants, and those of the Oxalis Lent. are so sensitive that the least motion, even a breath of air, will make them close."—Sir J. Smith.
"The vitality of plants seems to depend upon the existence of an irritability, which although far inferior to that of animals, is nevertheless of an analogous character."—Lindley's Introduction to Botany.
[12] Provincial Medical and Surgical Journal. July 10th, 1850. No. xiv. p. 367. "Practical Observations on the Vaccination Question." By E. Oke Spooner, M. R. C. S., Blandford.
"If we examine the Cow Pox and the Small Pox microscopically, as I have done very carefully in every stage, we find that the essential character consists of a number of minute cells, not exceeding the 10,000th part of an inch in diameter, being about one-fourth smaller than the globules of the blood, containing within their circumference many still more minute nuclei, and presenting beyond their circumference bud-like cells of the same size and character as those contained within the circle. They exactly resemble in everything except the size, the globules of the yeast plant, the Torula Cerevesiæ. Now if we examine more circumstantially the analogies of what I would call the Torula Variolæ with the Torula Cerevesiæ, we observe the following corresponding facts.
"What do we accomplish by inoculation as it is called? Simply this. We take on the top of a lancet, or an ivory point, a few of these minute cells or germs, and we put them in their appropriate nidus, the subcuticular tissue, where, after a few days if they find their appropriate nutrient elements, they grow and multiply."
Simon, Chemistry of Man, vol. i. p. 127. "Macgregor ascertained that the air expired by persons ill of confluent Small Pox, contained as much as eight per cent of carbonic acid, and in proportion as health was restored the percentage was diminished to its natural standard." Carbonic acid is also produced during the process of fermentation and germination.
[13] See History of the Jews, p. 71.
[14] It is said by Whewell, that the murrain is supposed to have fallen only on the animals which were in the open pasture.—History of the Jews.
"J. S. Michael Leger, published at Vienna, in 1775, a treatise concerning the mildew as the principal cause of the epidemic disease among cattle. The mildew is that which burns and dries the grass and leaves. It is observed early in the morning, particularly after thunder-storms. Its poisonous quality, which does not last above twenty-four hours, never operates but when it is swallowed immediately after its falling."—Mitchell on Fevers.
[15] "The prevalence of the south-east wind was observed to be particularly favourable to the increase of both cholera and influenza: and I cannot but think that this had some connexion with the general tendency exhibited by the former to spread from east to west. Has the morbific property of this wind aught to do with the haziness of the air when it prevails—a haziness seen in the country remote from smoke, and quite distinct from fog? What is this haze? In the west of England a hazy day in spring is called a blight."—Dr. Williams' Principles of Medicine.
[16] We are to understand also that some peculiar operation took place of a nature difficult to comprehend, which seems also to typify reproduction, for the handfuls of ashes which Moses threw into the air became a dust in all the land of Egypt, thus signifying an enormous reproduction of atomic matter.
[17] The Chinese affect to trace the origin of Small Pox back to a period of at least 3000 years, or 20 years beyond the era of the Trojan war, 1212, A. C.
The Chinese pretend to discriminate no less than 40 different species of Small Pox.
"They also pretend to discover whether a person has died by violence or from natural causes, not only after the body has been some time interred and decomposition of the softer parts has commenced, but even after the total disappearance of the soft parts, and when the dry skeleton alone is left."—For the process, see Hamilton's History of Medicine, vol. i. p. 31.
To give some notion of the state of Medical Science among the Chinese, I may quote the following: "The theory of the circulation of the blood, Du Halde affirms, was known by the Chinese about 400 years after the deluge; be this assertion veracious or not, no correct knowledge up to the present day, do the nation possess of the circulating system of the human frame."—China and the Chinese, Henry Charles Sirr, M. A.
According to their anatomy, the trachea extends from the larynx through the lungs to the heart, whilst the œsophagus goes over them to the stomach.
[18] "And Aaron took as Moses commanded, and ran into the midst of the congregation: and behold the plague was begun among the people; and he put on incense and made an atonement for the people. And he stood between the dead and the living, and the plague was stayed."—Numbers.
The practice of burning scented herbs has been observed in all times during an invasion of the plague, as a means of protection. Also wearing perfumes and aromatic preparations has been recommended. Whether they have any counteracting influence, it is impossible to say.
Virgil in the third Georgic speaks of a murrain among cattle. He says, if any wore a vestment made of wool from an infected sheep, fiery blains and filthy sweat overspread his body, and ere long a pestilential fire preyed upon his infected limbs.
In his directions for preserving the health of flocks he says—
"Disce et odoratam stabulis accendere cedrum."
The motive for burning the fragrant cedar is not mentioned; we cannot doubt but it was a good one, and having some great practical utility, from the following line—
"Galbaneoque agitare graves nidore chelydros."
[19] The earliest mention of this complaint upon which reliance can be placed, is an ancient Arabic MS. preserved in the public library at Leyden. "This year, in fine, the Small Pox and Measles made their first appearance in Arabia." The year alluded to being that of the birth of Mahomet, or the year 572 of the Christian æra.—Hamilton's History of Medicine, vol. i. p. 215.
[20] Dr. W. A. Greenhill's translation.
[21] The Black Assize at Oxford, 1572, is an instance in which a pestilential vapour suddenly appeared in the court, "whereby the judge, several noblemen, and more than 300 others, died within three days."
"Of an unaccountable vapour suddenly coming, I have this relation from Richard Humphrey, my neighbour, and a man of veracity, that on Wednesday, April 27, 1727, as he and one Walter, were travelling a-foot from Canterbury; when they came to Rainham, they were assaulted with such a strong loathsome stink, as he thought was like the stench from a corrupted human corpse. They were so offended at it, as thinking it was from carrion in that town, that they would not stay there to rest and refresh themselves, but travelled on for about two hours, mostly in the stench, but sometimes out of it, till they came to the hill that leads down to Chatham: and there they went clear out of it and smelt it no more."—Dr. Fuller.
It appears that these persons did not fall sick of any disease, but the fact of itself is remarkable enough.
[22] Hamilton's History of Medicine.
[23] It has been said, that "an induction once carefully drawn, is as perfect from a single instance as it is from ten thousand, and that it is only an uncultivated mind which requires a load and accumulation of knowledge to assist his thoughts."—Sewell "on the Cultivation of the Intellect."
[24] See Dr. Alison's Pamphlet on the Fever in Edinburgh.
[25] Earthquakes have in all times been considered to have some connexion with pestilences. "A most grievous pestilence broke out in Seleucia, which from thence to Parthia, Greece, and Italy, spread itself through a great part of the world, from the opening of an ancient vault in the temple of Apollo, and that it raged with so much fury as to sweep away a third part of the inhabitants of those countries it visited."—Dr. Quincy, on the Causes of Pestilential Disease.
"Upon an earthquake the earth sends forth noisome vapours which infect the air; so it was observed to be at Hull in Yorkshire, by the Rev. Mr. Banks, of that place, after a small earthquake there in 1703, it was a most sickly time for a considerable while afterwards, and the greatest mortality that had been known for fifteen years."—Anonymous, 1769.
[26] See Sharon Turner's Sacred History, text and notes, vol. i. p. 161 & 162.
"Each seed includes a plant; that plant, again,
Has other seeds, which other plants contain,
Those other plants have all their seeds; and those
More plants, again, successively enclose.
Thus ev'ry single berry that we find,
Has really in itself whole forests of its kind.
Empire and wealth one acorn may dispense,
By fleets to sail a thousand ages hence;
Each myrtle-seed includes a thousand groves,
Where future bards may warble forth their loves."
[28] "On June 5th, 1849, a man and his son, a lad aged 14 years, left Noss to fish, and when five miles out at sea, no vessel being in sight, they both simultaneously became aware of a hot offensive stream of air passing over them. It was so decided, that the crab pots were examined to discover if it were from them, but it did not, and five minutes after the father's attention was directed to the boy, who was vomiting and purging."—Dr. Roe on the Cholera at Plymouth, Med. Gaz. Aug. 24th, 1850.
[29] Linnæus remarked that Erigeron Canadense was introduced into gardens near Paris from North America. The seeds had been carried by the wind, and this plant was in the course of a century spread over all France, Italy, Sicily and Belgium.
[30] Hecker.
[31] This is found most generally to be the case where rivers flow through uncultivated tracts of country. The Californian emigrants suffer much from diarrhœa and dysentery, if they drink of the river and certain well waters of that gold district.
[32] "Purification from leprosy. As this fearful disease was contagious and hereditary to the third and fourth generation, the separation of lepers from the camp and congregation, and the destruction of infected houses and clothes, was of the utmost importance to the preservation of public health.
"Leprosy was of three kinds: 1st, Leprosy in man. 2nd, Leprosy in houses. 3rd, Leprosy in clothes.
"Contagious or malignant leprosy was of two kinds, viz.
"1st. The white leprosy, or bright berat, which was the most serious and obstinate form which leprosy assumes. It exhibited itself as a bright white and spreading scale, on an elevated base; turning the hair white in patches, which were continually spreading.
"2nd. The black leprosy, or dusky berat, which was less serious than the foregoing. It did not change the colour of the hair, nor was there any depression in the dusky spot; but the patches were perpetually spreading, as in the white leprosy."—Analysis and Summary of Old Testament History. Oxford.
[33] The Mexican Aloe blows when nine years old, and then dies. At least this is its usual course in the island of Cuba.
[34] "Ground that has not been disturbed for some hundred years, on being ploughed, has frequently surprised the cultivator by the appearance of plants which he never sowed, and often which were then unknown to the country. The principle has been ascertained to be capable of existing in this latent state for above 2000 years, unextinguished, and springing again into active vegetation, as soon as planted in a congenial soil.
"In boring for water near Kingston on Thames, some earth was brought up from a depth of 360 feet, and though carefully covered with a hand-glass to prevent the possibility of other seeds being deposited on it, was yet in a short time covered with vegetation.
"Turner says, from the depth, these seeds must have been of the diluvian age."—Jesse's Gleanings.
[35] Hamilton's History of Medicine, vol. ii. p. 276, note.
[36] "What I wish you to remark is this, that while almost all men are prone to take the disorder, large portions of the world have remained for centuries entirely exempt from it, until at length it was imported, and that then it infallibly diffused and established itself in those parts."—Dr. Watson on the Principles and Practice of Physic.
Dr. R. Williams says, "The seeds of intermittent fever lay dormant for months, it was not at all uncommon for cases of intermittent fever to be brought into the hospital eight or ten months after the patients had subjected themselves to the influence of paludal or marsh effluvia."
[37] I have observed in the hot-houses, that many of the exotic plants, which are in company with the diseased vines, have been attacked, while others again have been entirely free.
[38] By causes of the greatest variety plants may become extinct for a time. It is not very easy to trace them, but one fact may be mentioned in proof of the statement. Dr. Prichard states that vast forests are destroyed either for the purpose of tillage or accidentally by conflagrations. "The same trees do not reappear in the same spots, but they have successors, which seem regularly to take their place. Thus the pine forests of North America when burnt, afford room to forests of oak trees."
[39] Hecker says of Chalin de Vinario, that "he asserted boldly and with truth, that all epidemic diseases might become contagious, and all fevers epidemic,—which attentive observers of all subsequent ages have confirmed." P. 60.
[40] In 1539, the thirty-first year of Henry the Eighth, was great death of burning agues and flixes; and such a drought that welles and small rivers were dryed up, and many cattle dyed for lacke of water; the salt water flowed above London Bridge.—Stowe.
In 1556, the fourth of Mary, and the third of Philip, about this time began the burning fevers, quarterne agues, and other strange diseases, whereof died many.—Stowe.
The next winter, 1557, the quarterne agues continued in like manner, or more vehemently than they had done the last yere.—Stowe.
[41] Every writer on the climate of Egypt has remarked, that the Endemic Fever which is so frequent, originating on the coast, particularly about Alexandria, becomes occasionally so virulent, that it cannot be distinguished from the true Plague.—Robertson on the Atmosphere, vol. 2. p. 384.
"Endemial Fevers of every situation become occasionally so aggravated, that they cannot be distinguished from such as originate from contagion; and in every unusual virulence of this Endemic Fever, it is probable that it may be propagated afterwards by contagion as every epidemic." Ibid. p. 388.
[42] Dr. Ure.
[43] "The metamorphosis of starch into sugar depends simply, as is proved by analysis, on the addition of the elements of water. All the carbon of the starch is found in the sugar; none of its elements have been separated, and except the elements of water, no foreign element has been added to it in this transformation."—Liebig, Organic Chemistry, p. 71.
[44] As regards starch there appears to be some peculiar faculty regarding it. It is converted into sugar during the ripening of fruit, and it is just possible that being as it is of a cellular nature, the property of vitality may attach to it until it has, by being converted into sugar, fulfilled its destination.
[45] Though I do not consider that the fermentation process is a fac-simile of diseased action, yet I think its phenomena generally afford an apt illustration of the changes which may be effected by living germs. Many able chemists still maintain the entire dependence of fermentation upon the Torula: "M. Blondeau propounds the view that every kind of fermentation is caused by the development of fungi."
The varieties of opinions found in the literature of this subject, forms a curious specimen of scientific enquiry, and is sufficient alone to convince us of its vast importance and extensive relations.
[46] By Dr. Mantell.
[47] Mitchell on Fevers.
[48] We wonder, and ask ourselves: "What does SMALL mean in Nature?"—Schleiden's Lectures on Botany.
[49] Speaking of the bunt in wheat: "It appears certainly to be contagious, from numerous experiments, which shew that the contagious principle lasts a long time. I have tried it myself; some, however, doubt it, but it cannot be denied, that seed sown, infected with bunt, produces plants similarly affected; every one who has had the slightest experience must be convinced of it."—Essay on the Diseases of Plants. Count Ré.
[50] We have already spoken of the effects of these poisons, and have stated that the amount of each poison capable of destroying the body is pretty accurately known.
[51] The italics are my own.
[52] Gmelin says: "But the mode of action in these transformations, sometimes admits of other explanations; and when this is not the case, our conception of it is by no means sufficiently clear to justify the positive assumption of this, so called contact-action or catalytic force, which, after all, merely states the fact without explaining it"—Gmelin's Hand-book of Chemistry, vol. i. p. 115.
[53] The history and symptoms of some epidemic diseases, such as cholera and influenza, are not inconsistent with the hypothesis that they are caused by the sudden development of animalcules from ova in the blood. But there is a total want of direct observation in support of this hypothesis.—Dr. Williams' Principles of Medicine.
[54] Since writing the above, I have referred for information on this subject, and find, that the Anguillula aceti exhibits sexual distinctions; and that the ovaries of the females are situated on each side of the alimentary canal.—Cyclo. Anat. and Phys. Art. Entozoa.
[55] Speaking of the examination of the infusory animalcules—Mr. Kirby says: "But to us the wondrous spectacle is seen, and known only in part; for those that still escape all our methods of assisting sight, and remain members of the invisible world, may probably far exceed those that we know."—Bridgewater Treatise, vol. i. p. 158.
[56] Mr. Owen has added another class, as the first, called Protelmintha, which comprises the cercariadæ and vibrionidæ.
[57] "It is probable that in the waters of our globe an infinity of animal and vegetable molecules are suspended, that are too minute to form the food of even the lowest and minute animals of the visible creation: and therefore an infinite host of invisibles was necessary to remove them as nuisances."—Bridgewater Treatise, vol. i. p. 159.
"When Creative Wisdom covered the earth with plants, and peopled it with animals, He laid the foundations of the vegetable and animal kingdoms with such as were most easily convertible into nutriment for the tribes immediately above them. The first plants, and the first animals, are scarcely more than animated molecules,* and appear analogues of each other; and those above them in each kingdom represent jointed fibrils."†—Bridgewater Treatise, vol. i. p. 162.
* Globulina and Monus. † Oscillatoria and Vibrio.
[58] "A treatise which should present a systematic arrangement of all the diseases of plants, giving in detail the exact history of each, and adding the means of preventing and curing them, would certainly be of the greatest utility to agriculture." —Essay on the Diseases of Plants, Count Philippo Ré, translated into Gardener's Chron.
[59] "Plenck published a treatise on Vegetable Pathology, in which he divided diseases into eight classes: 1. External injuries; 2. Flux of juices; 3. Debility; 4. Cachexies; 5. Putrefactions; 6. Excrescences; 7. Monstrosities; and 8. Sterility. And he concludes with an enumeration of the animals which injure plants."—Essay on the Diseases of Plants, Gardener's Chronicle.
[60] The Bunt. "This disease appears at the moment of the germination of the plant. The affected individuals are of a dark green, and the stem is discoloured. As the ears are issuing from the sheaths, their stalks are of a dark green, but very slender. When the ear has fully grown out, its dull, dirty colour, causes it to be immediately distinguished from the healthy ones, and it soon turns white."—Essay on the Diseases of Plants.
[61] Vidi understood.
[62] "At the close of the year 1665," says Dr. Hodges, "even women, before deemed barren, were said to prove prolific."
"After the cessation of the Black Plague, a greater fecundity in women was every where remarkable—a grand phenomenon, which from its occurrence after every destructive pestilence proves to conviction, if any occurrence can do so, the prevalence of a higher power in the direction of general organic life. Marriages were almost without exception prolific; and double and treble births were more frequent than at other times."—Hecker, p. 31.
[63] It is stated that on the decline of the Plague, 1665, those who returned early to London, or new comers, were certain to be attacked. In proof of this the 1st week of November, the deaths increased 400, and "physicians reported that above 3000 fell sick that week, mostly new comers."
See also Dr. Copland's Dict. Pract. Med. Epidemic and Endemic Diseases.
"The hardy mountaineer is a surer victim of paludal fever, whether he visits the low countries of the tropics, or the marshes of a more temperate climate, than the feebler native of those countries."—Dr. R. Williams on Morbid Poisons.
[64] "Substances presented to the gastro-intestinal surfaces, are mixed up with various secretions, mucus, saliva, gastric juice, bile, pancreatic liquor, and special exudations from the peculiar glands of each successive section, while aerial poisons, unmixed and unfettered, are applied at once to a surface on which, behind scarcely a shadow of a film, circulates the blood prepared, by the habitual action of the respiratory function, to absorb almost every vapour, and every odour, which may not be too irritating to pass the gates of the glottis."—Mitchell on Fevers.
[65] Hecker on the "Black Death."
[66] The stomach in some cases is no doubt the medium by which some diseases are contracted. It is well known, that in many places the water induces diarrhœa, the permanent residents, however, may not suffer, but all new comers are more or less affected by drinking it.
[67] "Similar effects have been experienced from the use of mouldy provisions."—Dr. Lindley's Vegetable Kingdom.
[68] "Untold numbers die of the diseases produced by scanty and unwholesome food."—Southey.
A large, nay, a most extensive adulteration of flour with plaster of Paris was detected not many years since. The flour was supplied by a contractor for the manufacture of biscuits for the navy.
[69] See Southey's Doctor, vol. ii. interchapter vi. p. 115, for an illustration of this subject.
[70] Both these patients died.
[71] "A good part of the clove trees which grew so plentifully in the island of Ternate, being felled at the solicitation of the Dutch, in order to heighten the price of that fruit, such a change ensued in the air, as shewed the salutary effect of the effluvia of clove trees and their blossoms; the whole island, soon after they were cut down, becoming exceeding sickly."
[72] The observation is originally taken from the City Remembrancer, 133.
[73] See Hamilton's History of Medicine, vol. i. p. 4.
[74] Feuchtersleben's Medical Psychology, p. 176, 177.
[75] Ibid. p. 321.