INDEX

A-amino-acids, [61]
Aborigines, gout unknown among, [2]
Abscess formation in peri-tophal tissues, [234]
skin resembling, in acute gout, [212]
“Accessory food factors” in diet of gouty, [339]
Adenase, [100], [101]
Adenine, [73], [75], [77], [98]
Aetius’s views on gout, [6]
Age factor in gout, [40]
influence of, on diet, in acute stage of gout, [333]
Agotan in treatment of acute gout, [379]
Aix massage baths, [427]
Alanine, uric acid excretion augmented by, [89]
Albuminuria, diet in, [358]
Alcohol and gout, [48]
hypersensitiveness of gouty to, [365]
in febrile stage of sthenic gout, [333]
in gout, [361]
in subjects of gouty glycosuria, [237]
modus operandi of, in induction of gout, [49]
plus overeating, cause of gout, [49]
Alcoholism, chronic, purin metabolism in, [115]
Alexander of Tralles’s views on gout, [5]
Alimentary canal, condition of, and gout, [174]
disorders, effects of radio-active waters on, [439]
tract, functional derangements of, in diagnosis of articular gout, [249]
X-ray examination of, in treatment of gout, [336]
Alkalies in inter-paroxysmal periods of gout, [392]
in treatment of acute gout, [383]
in treatment of chronic gout, [399]
Alkaline waters, simple, spas for, [441]
Alkapton in urine, [59]
Alkaptonuria, [69]
Allantoin, [104]
Alternatives in treatment of chronic gout, [401]
Alveolus, senile atrophy of, [329]
Amberg and Jones’ scheme of formation of uric acid, [104]
America, United States of, gout in, [47]
Amino-acetic-acid, [64]
Amino-acids and dicarboxylic amino-acids, [89]
deaminisation of, [62], [63]
fate of, [62]
in portal blood, [62]
in relation to gout, [64]
Amino-purins, as source of uric acid, [84]
Amylaceous dyspepsia, diet in, [351], [352]
Anacritical stage of depression, [211]
Anæmia in cases of long-standing gout, treatment of, [406]
retention capacity of tissues for uric acid in, [158]
Anatomical alterations in articulations, [54]
Anglo-Saxon period, prevalence of gout in, [2]
Animal cells, nucleic acid derived from, [98]
Animals, various, uric acid blood content of, [135]
Ankylosis in chronic gout, [287]
Anodyne preparations in treatment of acute gout, [384], [385]
Anodynes in acute gout, [383]
Antiquity of gout, [1]
Anuria, hysteria in, [126]
Aponeuroses, gouty polyarthritis in, [214]
Appendicitis, septic foci of, [184]
Appendix-dyspepsia, [184]
Arab physicians’ views on gout, [6]
Aretæus the Cappadocian’s views on gout, [4], [5]
Arterio-sclerosis, associated with gout, [245]
blood-content in, [127]
spa treatment of, [451]
Arthralgia, fleeting, [193]
Arthritic attacks, tophi formation preceding, [164]
iritis, [315]
Arthritides, specific infective, and gout, analogies between, [194]
Arthritis deformans, cleavage into two types, [18]
differentiation of, from chronic gout, [16]
rheumatoid, and osteoarthritis, [20]
Arthritis, gonococcal, acute, differential diagnosis from acute gouty polyarthritis, [270]
from gout, [259]
of tarsus and metatarsus, differential diagnosis from gout, [263]
gouty, [39]
definition of, [20]
frequency of tophi in, [255]
relation to local foci of infection, [185]
Greek designation, [3]
hæmophilia, differential diagnosis from chronic gout, [285]
infective, of undifferentiated type, differential diagnosis from acute polyarticular gout, [272]
skiagraphy in differential diagnosis of, [290]
non-gouty, hyper-uricæmia in, [140]
rheumatoid, [17]
differential diagnosis from chronic gout, [284]
local character of joint swellings, [284]
or atrophic, acute, differential diagnosis from acute gouty polyarthritis, [272]
skiagraphy in differential diagnosis of, [291]
syphilitic, differential diagnosis from chronic articular gout, [277]
secondary, differential diagnosis from acute gouty polyarthritis, [271]
tophi in relation to, [254]
Arthropathies, nerve, differential diagnosis from chronic gout, [284]
Articular gout, chronic, medicinal and other modes of therapy, [397]
etiological diagnosis, [247]
Articular lesions in chronic gout, distribution of, [226]
Asphyxias, local, of hands, in gout, [45]
Atophan, effect of, on exogenous purins, [110]
on uric acid excretion, [119]
indicated when gout attack imminent, [395]
in treatment of acute gout, [379]
in treatment of chronic gout, [403]
Auricular tophi, [202]
Auto-intoxication theory of gout, [182]
Auto-toxæmia theory of gout, [182]
Avicenna’s views on gout, [6]
Bacillus coli communis as causative agent in gout, [175]
Bacterial flora, intestinal, modifications in, [182]
Bacteriological examination in diagnosis of articular gout, [251]
Baillon’s dissociation of rheumatism from gout, [15]
Banting method in reduction of obesity, [357]
Barclay’s theories of ætiology of gout, [23]
Bath as residence for gouty, [419]
Bath waters, Sir W. Ramsay’s analysis of, [435]
Baths in treatment of gout, method of application, [427]
Beaumont, W. M., ocular disease in the gouty, [308]
Beauvais’s work on gout, [17]
Beer as beverage in gout, [362]
Benzoates in treatment of chronic gout, [401]
Berkart’s theory of ætiology of gout, [27]
views on gout, [56]
Beverages in gout, [359]
Bismuth carbonate in inter-paroxysmal periods of gout, [392]
Biurate of soda in gouty tophi, [151]
Blisters in treatment of acute gout, [386]
Blood, changes in, in acute gout, [210]
in chronic articular gout, [226]
in gouty polyarthritis, [216]
content in gout, [189]
count in acute gout, [211]
Blood, examination of, in diagnosis of articular gout, [251]
Blood, human, relationship between amounts of uric acid, urea and non-protein nitrogen in, [122]
in chronic interstitial nephritis, urates in, [120]
in disease, uric acid of, [137]
portal, amino-acids in, [62]
routine examination of, in diagnosis of articular gout, [249]
uric acid as normal constituent of, [135]
uric acid content of, and gout, relation between, [143]
effect of diet upon, [141]
effect of exogenous purins on, [137]
estimation of sources of fallacy, [145]
in gout, [133], [139]
uric acid in, [24], [34], [78]
discovery of, [21]
Folin and Denis’s method of determination, [133]
forms of, [145]
Gudzent and Schade’s theories, [79]
non-protein nitrogen and urea nitrogen in (table), [136]
variations in uric acid content independently of diet, [142]
Bodily conformation, and gout, [44]
Boils, gout following, [53], [178]
Bone, conditions of, revealed by skiagraphy, in diagnosis of gout, [286]
Bones, changes in, in gout, [53]
focal areas of rarefaction in, revealed by skiagraphy, [286], [287]
Brandy in gout, [371]
Bruce’s modes, [286]
Bunion, inflamed, differential diagnosis from gout, [261]
Burian and Schur’s researches on sources of uric acid, [83]
Bursæ, involved in gout, [195]
tophi in, [233]
Bursitis, olecranon, gouty, [215]
post-calcaneal, in referred pain in heel, [265]
Cælius Aurelianus’s views on gout, [5]
Caffeine, [85]
Calcium carbonate in inter-paroxysmal periods of gout, [392]
salts in gouty tophi, [151]
Calculus, urinary, [29]
Carbohydrates in diet of gouty, [347]
Carbuncles, gout following, [53], [178]
Cartilage, morbid changes in, [53]
uratic deposits in, [52], [153]
in nephritis, [128]
Cataphoresis in treatment of chronic articular gout, [407]
Cell protoplasm, chemistry of, [176]
Celsus’s views on gout, [4]
“Chalk-stones,” [150]
Chalybeate waters, spas for, [442]
Champagne in gout, [368]
Charcot’s discovery of nerve arthropathies, [18]
joint, differential diagnosis from chronic articular gout, [277]
Chemistry of uric acid and purin bodies, [75]
Chilblains confused with early stages of tophi formation, [164]
Chirargra, Greek designation, [3]
Cholecystitis, [184]
Cider as beverage in gout, [363]
Claret in gout, [369]
Climate and gout, [45]
and residence in treatment of gout, [418]
Climato-therapy in gout, [418]
Clothing, importance of, [421]
Cocoa as beverage in gout, [361]
Coffee as beverage in gout, [361]
Colchicine in treatment of acute gout, [378]
Colchicum in acute gout, [192], [374], [375], [378]
contra-indicated, alkalies as substitute, [383]
method of administration, [376]
preparations and dosage of, [376]
used by Aetius, [6]
Colitis, mucous, initial manifestations of gout, [175]
Colloids in gouty tophi, [152]
Collosol iodine in treatment of chronic gout, [402]
Colorimetric method of determining uric acid in blood, [133]
Colour reaction test in blood analysis, [133]
Condiments in diet of gouty, [350]
Constipation, effect in gout, [337]
in acute gout, treatment of, [373]
in chronic gout, treatment of, [400]
in inter-paroxysmal periods of gout, treatment of, [393]
Constitutional disturbance in gout, [188]
influences in formation of tophi, [161]
Corpora cavernosa of penis, tophi in, [235]
Cramps in acute gout, [210]
Cream, effect of, on uric acid output, [348]
Creatine, [63], [67]
in urine of children, [68]
Creatinine, [61], [63], [67], [68]
in blood in gout and nephritis (table), [121]
Crystalline deposits in synovial fluid, [54]
Crystalloids in gouty tophi, [152]
Cytosine, [98]
Cullen’s differentiation of varieties of rheumatism, [16]
theory of ætiology of gout, [21]
Cutaneous disorders in gout, [240]
gravel, [203]
Cuticule, desquamation of, typical of gout, [191]
Cystin in urine, [59]
Cystinuria, [69]
Cystoid degeneration in gout, [56]
Deaminisation of amino-acids, [62], [63]
Deficiency diseases and accessory food factors, [340]
Degeneration, theories of, [25], [27]
Desquamation in acute gout, [212]
Diabetes, glycosuria and, [60]
Dicarboxylic amino-acids, [89]
Diet, effect of, on blood content of uric acid, [141]
Diet on excretion of uric acid, [83]
Diet in acute paroxysms of gout, [332]
in albuminuria, [358]
in amylaceous dyspepsia, [351], [352]
in chronic gout, [334]
in glycosuria, [357]
in hyperchlorhydria, [353]
in hyperuricæmia, [354]
in hypochlorhydria, [354]
in inter-paroxysmal periods of gout, [391]
in reduction of obesity, [357]
in treatment of gout, [332]
“accessory food factors,” [339]
carbohydrates, [347]
collaboration of clinician and bio-chemist, need for, [337]
condiments, [350]
fats, [347]
fish, [346]
fruits, [349]
idiosyncrasies of, [343]
physical examination necessary before, [336]
proteins, [345]
regulations of, [342]
vegetables, [348]
variations of blood content of uric acid independently of, [142]
Dietaries, fixed, fallacy of, in treatment of gout, [335]
Digestion, disturbances of, prevention of, in treatment of gout, [335]
Digestive glands, rôle of, in uric acid excretion, [88]
Diocletian, edict by, re gout, [5]
Dislocations, signalising attack of gout, [53]
Douches, [428]
Dover’s powder, with aspirin and phenacetin, in treatment of acute gout, [383]
Drink and gout, [48]
“Drug dyspepsia,” [391]
Drugs influencing excretion of endogenous uric acid, [96]
Duckworth’s classification of arthritic type of gout, [36]
theory of ætiology of gout, [33]
Dyschezia and gout, [337]
Dysenteric arthritis, differential diagnosis from acute gouty polyarthritis, [272]
Dysentery, complicated by arthritis and myalgias, [194]
Dyspepsia, amylaceous, diet in, [351], [352]
atonic, muriated waters in treatment of, [444]
chronic, gout associated with, [178]
“drug,” [391]
gouty, no specific form of, [350]
intestinal, preceding gout, [182]
mineral waters in treatment of, [443]
spas in treatment of, [442]
Dyspeptic symptoms of acute localised gout, [201]
Ear, pricking or tenderness in, [203]
tophus in, [202]
Ears, tophi in, antedating articular outbreaks, [203]
Ebstein and Sprague’s analysis of tophi, [150]
Ebstein’s theory of ætiology of gout, [25]
Ecchymoses, local, in acute gout, [212]
Eczema, gouty, spa treatment of, [451]
treatment of, [416]
in gout, [241]
Egypt, osteoarthritis in, in ancient times, [1]
Endemic areas of gout, [46]
Endogenous purins, [87]
origin of, [83]
source of, [88]
uric acid excretion, [91]
factors influencing, [93]
increased by purin-free proteid food, [89]
pathological states influencing, [94]
periodic variations of, [94]
physiological conditions, [93]
Environment in gout, [40]
Enzymes, distribution of, [99]
in intestinal juices and wall, [100]
Epistaxis, gout following, [178]
Epithelial cells, nucleus in gouty tophi, [151]
Erysipelas, gouty arthritis simulating, [215]
Erythromelalgia, differential diagnosis from gout, [266]
Etiological diagnosis of articular gout, [247]
Exercise in gout, importance of, [421]
relation of, to gout, [337]
Exogenous origin of purins, [83]
purins as source of uric acid, [84]
uric acid excretion, [85]
Exudative diathesis, [116]
Eye, deposition of urates in, [309]
gout in, evidence of, [309]
gouty diathesis in regard to, [310]
Eyelids, uratic deposits in, [235]
Fæces, examination of, in diagnosis of articular gout, [250]
in treatment of gout, [337]
Fasciæ, involved in gout, [195]
“Fat soluble A,” [340]
Fats in diet of gouty, [347]
Feet, incidence of tophi in, [162]
plantar surface of, tophi in, [235]
Fibrosis, interstitial, chronic, [186]
of visceral organs in gout, tendency to, [186]
Fibrositis associated with acute articular gout, [195]
associated with gout, treatment of, [411]
gouty, acute brachial, treatment of, [412]
incidence of gouty stigmata in types of, [221], [222]
muscular, in gouty, massage in, [423]
spa treatment of, [450]
Fingers, deformed, in chronic gout, [230]
pulps of, tophi in, [235]
Fischer’s researches on protein molecule, [61]
Fish in diet of gouty, [346]
Flatfoot, pains in, differential diagnosis from gout, [263]
“Flying gout,” [193]
Foci of infection in gouty, [53]
local, in gout, [177]
Foci, relation to gouty synovitis and arthritis, [185]
Folin and Denis’s method of determination of uric acid in blood, [133]
researches into urea formation, [63]
Food, cooking of, in diet of gouty, [344]
influence on gout, [48]
Foods, various, exogenous urinary purin in, amount of, [85]
Foot deformities, static, differential diagnosis from gout, [261]
“Fot-adl,” Anglo-Saxon name for gout, [3]
Fractures, signalising attack of gout, [53]
Fruits in diet of gouty, [349]
Function, gout a disorder of, [200]
Functional disturbances in gout, [201]
Galen’s views on gout, [2], [4]
Gall-stones, gout associated with, [184]
Gall-bladder dyspepsia, [184]
Garrod’s discovery of uric acid in blood of gouty persons, [21]
pathogeny of gout, growing scepticism as to, [32]
theory of ætiology of gout, [22]
views on gout in the eye, [320]
Gastralgias in gouty, [351]
Gastric catarrh, chronic, gout associated with, [351]
chronic, mineral waters suitable for, [445]
glands, diseased conditions of, and gout, [173]
insufficiency, muriated waters in treatment of, [444]
Gastro-intestinal asepsis, importance of, in gout, [332]
derangements in acute paroxysms of gout, [333]
disorders and gout, [180]
attributed to gout, [299-302]
chronic, spas in treatment of, [442]
mineral waters in treatment of, [443]
tract, derangement of, cause of gout, [170]
Genito-urinary passages, infection of, examination for, in diagnosis of articular gout, [249]
tract, examination of, in treatment of gout, [331]
Geographical distribution of gout, [45-48]
Gin in gout, [371]
Glandular affections in gouty subjects, [179]
Glaucoma, gout and, [324]
Glycocine and urea, interaction between, [84]
Glycocoll, rôle of, [64]
theory of gout, [65]
uric acid excretion augmented by, [89]
Glycosuria and diabetes, [60]
associated with gout, treatment of, [414]
diet in, [357]
examination for, in treatment of gout, [337]
gout and, co-existence of, [185]
gout in relation to, [236]
“gouty,” [182]
spa treatment of, [449]
Glyoxylic acid in gouty urine, [65]
Gonococcal arthritis of tarsus and metatarsus, differential diagnosis from gout, [263]
infection, articular involvement, with muscular and nervous lesions, [194]
differential diagnosis from gout, [259]
exclusion of, in diagnosis of articular gout, [248]
Gore, Ringrose, theory of pathology of gout, [173]
Gout, acute, colchicum in, [375]
definitely paroxysmal, [191]
general phenomena of, [210]
ionisation in treatment of, [387]
local phenomena, [211]
localised, clinical account, [200]
dyspeptic symptoms of, [201]
premonitory articular pains, [204]
prodromal symptoms, [200]
locality of, [208]
medicinal treatment of, [372]
onset of, [207]
pain in, [208]
paroxysm of, analysis of, [188]
diet in, [332]
symptoms of, [205]
uric acid variations in, [117]
surgical methods considered, [388]
treatment of, alternative remedies in, [381]
local measures, [384]
uric acid excretion in, [117], [211]
uric acid variations in, [108], [117]
ætiology of, histogenous theories of, [23]
nervous theories, [31]
summary of, [44]
theory of antecedent structural changes, [25]
age factor in, [40]
alcohol in, [361]
amino-acids in relation to, [64]
and fibrositis, incidence of, [221]
and granular kidney, clinical associations of, [130]
and immunity, early fallacies regarding, [10]
and nephritis, [242]
and other diseases, affinities between, [236]
and rheumatoid arthritis, resemblance between, [113]
and specific infective arthritides, analogies between, [194]
antiquity of, [1]
arterio-sclerosis associated with, [245]
articular, acute, differential diagnosis, [259]
localised, clinical diagnosis, [258]
chronic, [225]
alkalies in treatment of, [399]
blood changes in, [226]
clinical diagnosis of, [275]
distribution of, [226]
local measures in, [407]
medicinal and other modes of therapy, [397]
progress of disease, [228]
surgical treatment, [409]
classification of, author’s division, [38]
clinical diagnosis of, [252]
etiological diagnosis, [247]
manifestations of, [195]
as an infection, [177]
auto-intoxication theory, summary, [182]
beverages in, [359]
blood content in, [127]
uric acid and, relation between, [143]
choice of spa in treatment of, [440]
chronic, ankylosis in, [287]
confusion with chronic villous synovitis, [279]
diet in, [334]
differentiation of, from arthritis deformans, [16]
joint deformities of, [229]
of oligo-articular distribution, [278]
polyarticular, clinical features, [282]
polyarticular, differential diagnosis, [282]
tardy dissociation of, from chronic rheumatism, [15]
uric acid variations in, [109]
classification of, [35], [36]
climate and residence in treatment of, [418]
climato-therapy in, [418]
clinical account of, [200]
clothing and, [421]
collateral phenomena of, [219]
constipation and, [337]
cutaneous disorders in, [240]
definition of, [35]
author’s, [36]
derangement of gastro-intestinal tract as cause of, [171]
elimination of infective arthritides from domain of, [19]
endemic areas in, [46]
etiology of, [39]
evolution and life history of, [193]
excretion in, anomalies of, [112]
exercise in, importance of, [421]
false, ocular symptoms, [322]
glycocoll theory of, [65]
Greek physicians’ views of pathology of, [3]
growing infrequency and attenuation of, [12]
guanine, in swine, [100]
heredity and, [41]
hydrotherapy, general, in treatment of, [424]
local, in treatment of, methods of, [428]
hyperpyræmia in ætiology of, [30]
in big toe, differential diagnosis, [259]
infantile, [116], [305]
infective theory of, rise of, [171]
summary, [182], [183]
inflammatory phenomena in, cause of, [165]
initial attacks usually monarticular, [207]
initial outbreaks of, anomalous sites for, [267]
sites of, [37]
in relation to glycosuria, [236]
in relation to phlebitis, [239]
in the heel, [264]
in the instep, [262]
in the sole, [265]
inter-paroxysmal period, treatment in, prophylactic measures, [389]
introduction of word, [6]
irregular, [293]
conclusions regarding, [304]
isolation of acute articular rheumatism from, [15]
lead workers predisposed to, [50]
leanness in, [337]
leucocytosis in, [172], [189]
life history of, [193]
local foci of infection, [177]
treatment of, radical, [327]
local syncopes and asphyxias of hands in, [45]
long-continued, favouring onset of pre-senilism, [398]
lumbago associated with, [221]
massage, general, in treatment, [423]
metabolic phenomena correlated with postulated infective element, [195]
mineral springs in treatment of, [431]
monarticular, chronic, differential diagnosis of, [276], [277]
morbid anatomy of, [39], [53]
morbid conditions associated with, treatment of, [411]
obesity in, reduction of, [356]
ocular disease in, [308]
frequency a factor in diagnosis, [316]
onset of, symptoms, [188]
organic predisposition to, [43]
other conditions classified as, in early times, [12]
pathogenesis of, earlier theories of, [21]
pedigree of, [14]
periodicity of, [191]
phenomena of, detailed account of, [207]
predisposing causes of, summary of, [52]
prevalence of, in Anglo-Saxon period, [2]
prognosis in, [244]
renal theory of, [117]
restriction of, by elimination of other disorders, [19]
retarded purin elimination in, [118]
retention capacity of tissues for uric acid in, [158]
retrocedent, [39], [296]
irregular manifestations of, [299]
sex incidence of, [41]
skiagraphy in diagnosis of, [286]
specific organism suggested, [175]
sthenic, febrile stage of, alcohol and, [333]
structural changes, [54]
sub-infection theory, summary, [182], [183]
subjective phenomena of, in relation to blood content and excretion of uric acid, radium emanations and, [438]
“the honour of,” [8]
theory of hepatic inadequacy, [28]
tophaceous, [39]
treatment of, [327]
diet in, [332], [342]
fallacy of fixed dietaries, [335]
gastro-intestinal asepsis in, [332]
hyperæmia, [429]
physical examination necessary before dieting, [336]
prevention of digestive disturbances, [335]
uratic deposits in, [54]
differentiation from nephritis, [129]
localisation of, [153]
uratosis in relation to, [149]
urea excretion in, [66]
uric acid content of blood in, [139]
uric acid excretion in, [108]
anomalies in, [117]
uric acid in relation to, [107]
uric acid theory of, [21]
uric acid, urea and creatine in blood in (table), [211]
uricæmia in, [125], [133]
not cause, but result, of, [148]
variations in excretion in, diagnosis of, [60]
Gouty arthritis, definition of, [20]
phlebitis, [240]
polyarthritis, acute, [214]
stigmata in types of fibrositis, [222]
“Gravel, cutaneous,” [203]
immunity from, [29]
Greek physicians, terms used for forms of gout, [3]
views of pathology of gout, [3]
Guaiacum in treatment of chronic gout, [403]
resin, effects on urine, [405]
Guanase, [100], [101]
Guanine, [73], [75], [77], [98]
gout in swine, [100]
Gudzent and Schade’s theories of uric acid in blood, [79]
Gummata, peri-bursal, [281]
peri-synovial, [281]
Gums, recession of, early, [45]
Hæmatemesis, gout following, [178]
Hæmo-analysis, [147]
Hæmophilic arthritis, differential diagnosis from chronic gout, [285]
Hæmorrhage, retinal, and gout, [322]
Hair, premature whitening of, [45]
Hallux rigidus, differential diagnosis from gout, [262]
valgus with inflamed bunion, differential diagnosis from gout, [261]
Haly Abbas’s views on gout, [6]
Hand, gouty polyarthritis in, [214]
Hands, deformed, in chronic gout, [230]
incidence of tophi in, [162]
local syncopes and asphyxias in gout, [45]
palms of, tophi in, [235]
Hare’s theory of ætiology of gout, [30]
Heart affections in gouty subjects, [302]
Heberden’s differentiation of rheumatoid arthritis from gout, [17]
nodes, [41], [283]
Heel, gout in, [264]
referred pain in, differential diagnosis in, [264]
local sources of fallacy, [265]
Hepatic derangement in acute paroxysms of gout, [333]
inadequacy theory of ætiology of gout, [28]
Heredity in gout, [8], [28], [40], [41], [214]
Herpes in acute gout, [241]
Hexose group in vegetable nucleic acids, [98]
Hippocrates, aphorisms of, on gout, [4]
Histogenous theories of ætiology of gout, [23]
Historical survey, [1]
Horbaczewski’s experiments on uric acid, [73]
Hot-air baths, [429]
contra-indications to use of, [429]
Hutchinson on gout and rheumatism, [15]
Hydrarthrosis, bilateral, [281]
in chronic articular gout, [278]
Hydrochloric acid, secretion of, and gout, [173]
strong or fuming, in inter-paroxysmal periods of gout, [393]
variations in, and gout, [181]
Hydro-therapy, general, in treatment of gout, [424]
in acute gout, [385]
in treatment of gout, contra-indications and untoward complications, [425]
methods of application, [427]
prophylactic measures, [424]
local, in treatment of gout, [428]
Hyperacidity due to organic acids, [351]
in inter-paroxysmal periods of gout, [393]
Hyperæmia, treatment of gout by, [429]
Hyperchlorhydria, [181], [351]
associated with gout, treatment of, [415]
complicating gout, salt in diet contra-indicated, [350]
diet in, [353]
mineral waters suitable in treatment of, [446]
Hyperpyræmia in ætiology of gout, [30]
Hyperuricæmia, diet in, [354]
in gout, [140]
in non-gouty arthritis, [140]
ocular symptoms in, [321]
Hypochlorhydria, [351]
diet in, [354]
Hypoxanthine, [73], [75], [77]
Indigestion, intestinal, in gouty subjects, [181]
Infantile gout, [116], [305]
Infection in gout, local foci of, [177]
examination for in diagnosis of articular gout, [248]
theory of gout, [182], [183]
Infections, differential diagnosis from acute localised articular gout, [259]
specific, arthritic muscular and nerve lesions associated with, [195]
diagnosis of, [19]
Infective element in gout, correlated with metabolic phenomena, [195]
Inflammation and tophi formation, [164]
gouty, pus formation and, [191]
Inflammatory phenomena in gout, cause of, [165]
Influenzal arthritis, differential diagnosis from acute gouty polyarthritis, [272]
Immunity conferred by gout, early fallacies regarding, [10]
Inosinic acid, [93]
Instep, gout in the, [262]
Intestinal canal, source of microbe or toxin in gout, [181]
derangements, mineral waters suitable in treatment of, [448]
dyspepsia preceding gout, [182]
indigestion in gouty subjects, [181]
irrigation with radio-active waters, [439]
juices and wall, enzymes in, [100]
Iodides in treatment of chronic gout, [401]
value of, in renal and vascular changes, [403]
Iodine-albumen compounds in treatment of chronic gout, [402]
Iodo-glidine in treatment of chronic gout, [402]
Iodo-protein in treatment of chronic gout, [402]
Ionisation in treatment of acute gout, [387]
in treatment of chronic articular gout, [407]
Iritis, “arthritic,” [315]
diseases commonly associated with, [313]
gouty, “not” a clinical entity, [316]
in gout, [308]
relative incidence of, [313]
Irregular gout, [293]
Isomeric forms of uric acid, [81]
Isomers of purins, [81]
of pyrimidins, [81]
Jaw, formation of, [45]
Jaws, radiographs of, in treatment of gout, [328]
Joint cartilage, murexide reaction in, [153]
deformities of, chronic gout, [229]
Joints, diaphyses of, cystic changes in, [56]
rheumatism of, [14]
stiffness of, after acute attacks of gout, [212]
swellings, local character of, in osteo-arthritis, [283]
local character of, in rheumatoid arthritis, [284]
tophi in, [233]
Juices, gastric and intestinal, gout and, [173]
Kidney and kidneys, capacity of for eliminating uric acid, [125]
condition of, effect in blood content of uric acid, [138]
disease of, granular, and gout, clinical, association, [130]
joint examination in, results of, [129]
disease of, and gout, [242]
functionally deficient in late stage of gout, [119]
functional disorders of, [27], [28]
functional efficiency of, tests for, [338]
gouty, histological changes in, [127]
guanase in, [100]
uric acid elimination in, [119]
Knee, gouty polyarthritis in, [214]
site of primary attack of gout, [267]
Kossel’s discovery of purin bases, [73]
Labile protein, [59]
Latham’s theory of hepatic origin of gout, [29]
“Lead gout,” [50]
Lead, elimination by iodides, [403]
poisoning, blood content in, [122], [123], [127]
ocular symptoms in, [321]
purin metabolism in, [115]
workers, predisposed to gout, [50]
Leanness in gout, [337]
Lehmann’s analysis of tophi, [150]
Leucocytosis, [24], [27]
during acute attacks of gout, [172]
in gout, [189]
in gouty polyarthritis, [216]
relation to uric acid excretion, [95]
Leucopenia, [96]
in gout, [189]
Leukæmia, blood content in, [122], [123]
ocular symptoms in, [321]
uric acid in urine in, [95]
Levy’s (Magnus) researches on gout, [107]
Limbs, integument of tophi in, [235]
Lime salts, focal absorption of, in bones, [288]
Liniments in treatment of acute gout, [386]
Literature of various periods, references to gout in, [3]
Lithæmia, [294]
tendency to, [28], [33]
Lithiasis, [29]
Lithium salts in treatment of chronic gout, [400]
Lithuria, [29]
Liveing’s theory of ætiology of gout, [31]
Liver, diseases of, amino-acids in, [59]
disorders of, functional, mineral waters suitable in treatment of, [447]
enzymes in, [99]
functional efficiency of, tests for, [338]
glycogenic distension of, [31]
guanase in, [100]
main centre of production of urea, [63]
Living, style of, effect on incidence of gout, [2]
Locality, factor in gout, [45]
incidence of, in acute gout, [208]
Lucian of Saramosta’s views on gout, [4]
Lumbago, associated with gout, [221]
treatment of, [411]
Lung, guanase in, [100]
Lymph spaces, purins in, [146]
stream, sodium ions in, [146]
Lymphangitis, co-existent with gout, [58]
in gout, [190]
Lymphatic gland, enlargement of, in gout, [190]
Lymphatics, purins in, [146]
Malt liquors in gout, [362]
Marchand’s analysis of tophi, [150]
Massage, general, in treatment of gout, [423]
in after-treatment of acute gout, [385], [387]
McCarrison’s views on effect of absence of vitamines on functional efficiency, [340]
McClure and McCarty’s researches on bone conditions as revealed by skiagraphy, [288], [289]
Meat, over-eating of, functional damage resulting from, [65]
Meningococcal arthritis, differential diagnosis from acute gouty polyarthritis, [272]
Menstruation, effect of, on incidence of gout, [41]
Mental over-exertion and gout, [51]
Metabolic phenomena of gout correlated with postulated infective element, [195]
Metabolism, alterations in, [30]
inborn errors of, [69]
nuclein, [71]
protein, [59], [61]
Metastasis in relation to ocular gout, [314]
gouty, [297]
Metatarsalgia, differential diagnosis from gout, [262]
Methyl-purins as source of uric acid, [85]
Microbic theory of gout, [175]
Miescher’s researches on spermatozoa, [72]
on the nucleus, [71]
Milk diet in acute paroxysms of gout, [332]
Mineral springs, [431]
waters as beverage in gout, [360]
Monarticular gout, differential diagnosis of, [276], [277]
Morphia, hypodermic injections of, in acute gout, [383]
Mouth, examination of, in diagnosis of articular gout, [248]
in treatment of gout, [328]
local foci of infection, results of, [184]
Murchison’s theory of ætiology of gout, [28]
Murexide reaction in joint cartilage, [153]
Muriated chloride waters, spas for, [441]
sulphated waters, spas for, [442]
Muscles, affections of, in gout, [195]
voluntary, relation of creatinine to, [68]
Muscular exercise, uric acid excretion increased by, [93]
Myeloma, waste of albumoses in, [59]
Nails, striated, fluted and brittle, [45]
Nasal affections, radium emanations for, [438]
disorders, gout and, [178]
Naso-pharynx, examination of, in treatment of gout, [328]
foci of infection, [53]
Necrosis, local, in uratic deposition, [152]
relationship to gout, [25]
Nephritis, acute and chronic, blood content in, [127]
chronic, spa treatment of, [452]
complicating gouty polyarthritis, [219]
early, blood content of uric acid, urea and creatine, similarity to gout, [120]
gout and, [242]
gouty, treatment of, [416]
uratic deposits in, [128]
differentiation from gout, [129]
uric acid, urea and creatine in blood in (table), [121]
uricæmia in, [120]
uricæmia not peculiar to, [124]
Nerve arthropathies, differential diagnosis from chronic gout, [284]
Charcot’s discovery of, [18]
Nervous phenomena of gout, [188], [304]
system, effect of gout on, [219]
theories of ætiology of gout, [31]
Neuralgia, plantar, differential diagnosis from gout, [266]
Neuritis, alcoholic peripheral, [238]
glycosuric peripheral, [238]
Neuro-lymphatismus, [116]
Neuro-retinitis in the gouty, [324]
Neurosis, gouty, [31]
Neuroses, paroxysmal, of gout, [188]
Nose, alæ of, tophi in, [235]
Nuclease, [100]
Nucleic acid, [72], [77]
characteristic constituents of, [78]
disruption of, [100]
in body, [74]
formation of uric acid from, [98]
isolation of, [71]
metabolism of, in gout, [69]
molecules, [101]
of animal origin, structural formula of, [99]
physiological derivation of uric acid from, [73]
uric acid a derivative of, [73]
Nucleic-acidase, [100]
Nuclein, discovery of, [72]
metabolism, [71]
chemistry of, [60]
Nucleins, [77]
phosphoric acid group in, [112]
Nucleo-proteins, [77]
Nucleosidases, [101]
Nucleosides, [87], [100]
Nucleotidase, [100]
Nucleotides, [100]
Numbness after acute attacks of gout, [212]
Obesity and gout, [245]
Ebstein’s views of affinity, [280]
in gout, [337]
reduction of, [356]
Occupation and gout, [48]
Occupations predisposing to gout, [50]
Ocular disease in gout, [308]
Œdema in acute gout, [212]
in gouty conditions, [191]
Olecranon bursa, involved in gout, [215]
tophi in, [233], [235]
Oligo-articular distribution of chronic gout, [278]
Oral sepsis in gouty subjects, [179]
radium emanations and, [438]
treatment of, in gout, [330]
Ord’s theory of ætiology of gout, [25]
Osler’s views on gout, [36]
Osteoarthritis, acute, differential diagnosis from gout, [261]
and chronic articular gout, [275], [276]
co-existing with gout, [19]
differential diagnosis from chronic articular gout, [278]
differential diagnosis from chronic gout, [283]
in ancient civilisations, [1]
local characters of joint swellings, [283]
of hip, with auricular tophi, [226]
skiagraphy in differential diagnosis of, [291]
Overeating and gout, [48]
plus alcohol, cause of gout, [49]
Oxaluria associated with gout, treatment of, [413]
examination for, in treatment of gout, [337]
spa treatment of, [449]
Oxidation of purin, products of, [77]
Oxy-purins as source of uric acid, [84]
formation of, [102]
Pain and tophi formation, [164]
in acute gout, [208]
in auricular tophi, [233]
referred, in heel, differential diagnosis of, [264]
Pains, premonitory articular, in acute localised gout, [204]
Painters, predisposed to gout, [50]
Pancreas, enzymes in, [99]
Pancreatic inefficiency, evidence of, in diagnosis of articular gout, [250]
Pancretin, [392]
Papain, [392]
Parke’s theories of ætiology of gout, [23]
Parotitis, acute, gout following, [53]
in gout, [179]
Patella, tophi in, [235]
Pathological states influencing endogenous uric acid excretions, [94]
Paulus Ægineta’s views on gout, [6]
Pedigree of gout, [14]
Pentosuria, [69]
Peri-bursal gummata, [281]
Perineum, uratic deposits in, [235]
Periodic variations in excretion of endogenous uric acid, [94]
Periodontitis, chronic, [329]
Peri-synovial gummata, [281]
Pes planus, differential diagnosis from gout, [263]
Pharyngeal affections, radium emanations for, [438]
Pharyngitis, acute and chronic, in gouty subjects, [179]
acute, gout following, [53]
Pharynx, examination of, in diagnosis of articular gout, [249]
Phlebitis, gout in relation to, [239]
gouty, treatment of, [415]
in limb in articular gout, [190]
spa treatment of, [450]
treatment of gout and, [328]
Phospho-nuclease, [102]
Physical examination, necessity for, before dieting, in treatment of gout, [336]
over-exertion and gout, [51]
Physiognomy of the goutily disposed, [44]
Pinna, small red swellings on, [204]
Planchon’s views on gout, [6]
Plantar neuralgia, differential diagnosis from gout, [266]
Pleurodynia associated with gout, treatment of, [412]
Plumbers, predisposed to gout, [50]
Plumbism and gout, [60]
purin metabolism in, [115]
Pneumococcal arthritis, differential diagnosis from acute gouty polyarthritis, [272]
Podagra, [12]
Greek designation, [3]
Polyarthritis, articular, acute, differential diagnosis of, [269], [270]
gouty, acute, [214]
clinical diagnosis of, [268]
diet in, [334]
blood changes in, [216]
distribution of, [214]
effect on nervous system, [219]
simulating erysipelas, [215]
non-gouty, uric acid blood content in, [141]
Polyarticular distribution of gout, [214]
Poly-nucleotides, [100]
Port wine in gout, [364], [368]
Portal blood, amino-acids in, [62]
Post-critical stage of depression, [211]
Potash compounds in treatment of chronic gout, [400]
Potassium in gouty tophi, [151]
Prescriptions for use in acute gout, [375], [377], [378], [379], [380], [386], [391]
for use in chronic gout, [401], [405], [406]
for use in inter-paroxysmal periods of gout, [391], [392], [393], [394]
Pre-senilism, long-continued gout favouring, [398]
Protamine, [72]
Protein, amino-acids in, number of, [64]
chemistry of, [60]
labile, [59]
metabolism, [59], [61]
urine content of urea, etc., in, [59]
tissue, [59]
Proteins and their derivatives, [88]
in diet of gouty, [345]
Pulse quickened in gout, [189]
Purgatives in treatment of acute gout, [374]
Purin bases, toxicity of, discussed, [168]
bodies, [34], [48], [63]
chemistry of, [75]
diet, uric acid excretion in, [86]
“free” diet, [355]
uric acid blood content in, [137]
uric acid excretion in, [86]
elimination, retarded, in gout, [118]
metabolism, chemistry of, [60]
in chronic alcoholism, [115]
in other disorders, [113]
in plumbism, [115]
nuclease, [102]
nucleus, arrangement of atoms, [76]
oxidation of, products of, [77]
scheme illustrating probable stages in passage through body, [101]
synthesis in mammals, [97]
unexcreted, fate of, [87]
Purins, discovery of, [72]
endogenous, [83], [87]
source of, [88]
exogenous, [83]
as source of uric acid, [84]
effect of atophan on, [110]
effect on uric acid blood content, [137]
isomers of, [81]
of vegetable origin, [77]
Pus formation, non-existence of, in gouty inflammation, [186], [191]
Pyæmia, differential diagnosis from gout, [259]
Pyæmic conditions confounded with gout, [191]
Pyorrhœa alveolaris, and gout, [178]
and treatment of gout, [329]
exclusion of, in diagnosis of articular gout, [248]
Pyrexia in acute gout, [210]
in gout, [189]
Pyrimidine bases, [77]
Pyrimidins, isomers of, [81]
Quadriurate in blood, [78], [79]
Quinic acid in treatment of acute gout, [383]
Quinine in treatment of acute gout, [383]
Race incidence of gout, [45-48]
Radio-active properties of thermal waters, [427]
waters, physical properties of, [434]
Radium emanation, increased excretion of uric acid through, [437]
influence on uric acid metabolism, [436]
physiological action of, [435]
subjective phenomena of gout in relation to blood content and excretion of uric acid and, [438]
therapeutic action and application, [438]
Regular gout, [13]
Renal changes in gout, [54]
defect, uricæmia not necessarily due to, [123]
depression, functional, [119]
disease, abnormal protein loss in, [59]
theory of gout, [117]
uric acid infarcts, [151]
Residence, choice of, [420]
Respiratory disorders, spa treatment of, [450]
organs, affections of, in gout, [303]
Retinitis, nephritic, [324]
Retrocedent gout, [39], [296]
Rhazes’s views on gout, [6]
Rheumatism, acute articular, differential diagnosis from acute gouty polyarthritis, [269], [270]
isolation from gout, [15]
muscular and nervous lesions associated with, [194]
confused with gout, [215]
chronic, tardy dissociation of, from chronic gout, [15]
differential diagnosis from gout, [259]
early use of term, [14]
muscular, identification of, [16]
Rheumatoid arthritis, [17]
and gout, resemblance between, [113]
differential diagnosis from chronic gout, [284]
disturbance of purin metabolism in, [112]
or atrophic arthritis, differential diagnosis from acute polyarticular gout, [272]
Roberts’, Sir William, views on gout, [36]
Salicylate group as alternative remedy in treatment of acute gout, [381]
of colchicine in treatment of acute gout, [379]
Salicylates in treatment of acute gout, contra-indicated, alkalies as substitute, [383]
in treatment of chronic gout, [401]
Salisbury diet in hyperchlorhydria, [353]
method in reduction of obesity, [357]
Salt in diet of gouty, [350]
Scapular region, uratic deposits in, [235]
Scheele’s discovery of uric acid, [8]
Schnee four-cell bath in ionisation, [408]
Sciatica associated with gout, treatment of, [411], [412]
Scudamore’s definition of gout, [35]
Seneca’s views on gout, [5]
Septic conditions confounded with gout, [191]
Serapion’s views on gout, [6]
Serous membranes, uratic deposits in, in nephritis, [128]
Sex incidence in gout, [41]
Shivering at onset of acute paroxysm of gout, [188]
Sidonal in treatment of acute gout, [383]
Silk as underwear, [421]
Sinusitis, latent, cause of systemic infections, [331]
Skiagraphy in diagnosis of gout, [286]
in diagnosis of villous synovitis, [281]
in differential diagnosis of hypertrophic or osteo-arthritis, [291]
in differential diagnosis of infective arthritis, [290]
in differential diagnosis of rheumatoid or atrophic gout, [291]
Skin, action of, consideration of, in treatment of gout, [337]
appearances of, and gout, [45]
defective elimination by, in chronic gout, treatment of, [400]
Sodium biurate crystals in synovia, [52]
ions in lymph stream, [146]
mono-urate compound, [81]
salicylates of, in treatment of acute gout, [382]
Sole, gout in, [265]
Solubilities of uric acid and urates in gouty blood, [82]
Sool-Bader baths, [427]
Spa, choice of, in treatment of gout, [440]
treatment, duration of course of, [453]
in acute gout, [385]
of gout, principles of, [434]
remarks on, [452]
Spas from a national aspect, [454]
Spermatozoa, Miescher’s researches in, [72]
Spirits in gout, [370]
Spleen, enlargement of, in gout, [190]
enzymes in, [99]
functional efficiency of, tests for, [338]
Starchy foods in diet of gouty, [347]
Static foot deformities, differential diagnosis from gout, [261]
Stone in Norfolk, [29]
Streptococci in tonsils, [183]
Sub-infection theory of gout, [182], [183]
Sub-thermal baths, [428]
Succus entericus, action on nucleic acid, [100]
Sugar in diet of gouty, [347]
Sulphated alkaline waters, spas for, [442]
waters, [441], [442]
Sweetbreads in diet of gouty, effect of, [345], [346]
Swine, guanine gout in, [100]
Sydenham’s differentiation of rheumatism from gout, [15]
views on gout, [7]
Syncopes, local, of hand, in gout, [45]
Synovia, appearance in, in acute gout, [52]
Synovial fluid, reaction of, [52]
Synovitis, gouty, relation to local foci of infection, [185]
gummatous, differential diagnosis from chronic articular gout, [277]
of knees, differential diagnosis from gout, [264]
of tendo Achilles in referred pain in heel, [265]
perforative, [57]
villous, chronic, confusion with chronic gout, [279]
clinical symptoms of, [280]
static and non-gouty in origin, [280]
Synthetic formation as source of uric acid, [84]
of uric acid, [96]
Syphilis, articular, muscular and nerve lesions associated with, [194]
Syphilitic arthritis, secondary, differential diagnosis from acute gouty polyarthritis, [271]
disease of tarsal joints, differential diagnosis from gout, [263]
Taka-diastase, [392]
Tarsal joints, gonococcal arthritis of, differential diagnosis from gout, [263]
involved in gouty polyarthritis, [214]
tuberculous and syphilitic disease of, differential diagnosis from gout, [263]
Tartareous nature of tophi, views on, [8]
Tea as beverage in gout, [361]
Teeth, characteristic, in gout, [45]
conditions in gout, [178]
devitalised, examination of, in treatment of gout, [328]
foci of infection, [53]
Temperament, and gout, [44]
Temperature curve of gout, [188]
Tendo Achilles, involved in gout, [215]
Tendon sheaths, involved in gout, [195]
Tendons, gouty polyarthritis in, [214]
uratic deposits in, [153]
Test meals for HCL variations, [336]
Tests, modern, for uric acid determination, disabilities of, [147]
Theobromine, [85]
Theophyllin, [85]
Throat, gouty, [45]
Thymine, [98]
Thyminic acid, [80]
in treatment of acute gout, [383]
Thymus, enzymes in, [99]
gland, nucleic acid derived from, [98]
in diet of gouty patients, effect of, [345], [346]
Tibia, tophi in skin over, [235]
Tissue affinities for uric acid, [157]
protein, [59]
Tissues, human, concentrations of uric acid in, [159]
retention capacity of, for uric acid, [158]
effect on blood content, [138]
Toe, big, gout in, differential diagnosis of, [259]
initial outbreak of gout in, [37], [188]
Tonsil, site of infection in gout, [180]
Tonsillar sepsis, gout and, [178]
Tonsillitis, acute, gout following, [53]
in gouty subjects, [179]
treatment of, in gout, [330]
Tonsils, examination of, in diagnosis of articular gout, [249]
foci of infection, [53]
streptococci in, [183]
Tophaceous deposits in chronic articular gout, [227]
gout, [39]
Tophi, analysis of, [150]
antedating articular attacks, [202]
auricular, [202]
pain in, [233]
clinical evolution of, [162]
constitution of, [149]
constitutional influences in, [161]
diagnostic status of, [252]
difficulty in detecting, [256]
early stages of, confused with chilblains, [164]
early views as to nature of, [7]
evolution and distribution of, [231]
formation preceding arthritic attacks, [164]
frequency of, in gouty arthritis, [255]
gouty, causation of, [154]
formation of, [151]
localisation of, [153]
radiating, concentric and laminated structure of, [152]
urate of soda, [150]
importance of, in diagnosis of acute gouty polyarthritis, [269]
in diagnosis of gout, [38]
in eyes, significance of, [311]
inflammatory nature of swellings in, [163]
in relation to arthritis, [254]
in relation to uricæmia, [155]
sites of, [233]
stage of small red swellings, [163]
treatment of, in chronic articular gout, [407]
Tophus formation in acute gout, [212]
premonitory symptoms of, [203]
in ear, sign of gout, [202]
Trauma, local, effect on gout, [53]
Traumatic lesions, differential diagnosis from gout, [260]
Trousseau’s views on gout, [36]
Tuberculous disease of tarsal joints, differential diagnosis from gout, [263]
joint disease, differential diagnosis from chronic articular gout, [277]
Toxæmia, alimentary, hydrochloric acid, [394]
chronic, [182]
Toxicity, low, of chemical products, in gout, [69]
non-, of uric acid, [166]
Ulna, tophi in skin over, [235]
Uracil, [98]
Urate of soda in gouty tophi, [150]
Urates, deposition of, in eye, [309]
Uratic depositions as criterion of gout, [37]
deposits in gout, [54]
in gout and nephritis, differentiation of, [129]
in gout, localisation of, [153]
in nephritis, [128]
Uratosis in gout, [149]
Urea and glycocine, interaction between, [84]
end-product of protein metabolism, [63]
excretion in gout, [66]
excretion of ammonia as, [63]
formation of, [62]
Folin and Denis’s deductions, [64]
seat of, [63]
in blood in gout and nephritis (table), [121]
Ureters, ligature of, [26]
Uric acid, [75], [77]
a normal constituent in blood, [135]
an end-product, [70]
as a derivative of nucleic acid, [73]
blood content of, in various animals, [135]
variations independently of diet, [142]
chemical constitution of, [75]
concentrations in human tissues, [159]
content of blood and attacks of gout, relation between, [143]
in gout, [139]
deposition of, [22], [34]
destruction of, [98], [104]
determination of, disabilities of modern tests, [147]
diathesis, [294], [295]
discovery of, by Scheele, [8]
estimation of, sources of fallacy, [145]
excretions of, amount of, [75]
exogenous, [85]
in acute gout, [211]
in gout, [108]
anomalies in, [117]
increased by radium emanation, [437]
relation of leucocytosis to, [95]
exogenous purins as source of, [84]
formation of, Amberg and Jones’s scheme of, [103], [104]
from nucleic acid, [98]
gravel, spa treatment of, [451]
in the blood, [78]
forms of, [145]
in gout and nephritis (table), [121]
of gouty patients, discovery of, [21]
organic combinations of, [79]
infarcts, renal, [151]
in relation to gout, [107]
isomeric forms of, [81]
kidney capacity for eliminating, [125]
metabolism, influence of radium emanations on, [436]
non-toxicity of, [166]
of blood in disease (table), [137]
output, endogenous, lowered, [111]
exogenous, retarded, [109]
physical properties of, [78]
retention, capacity of tissues for, [158]
solubilities of, [154]
sources of, [83]
synthetic formation of, [84], [96]
theory of gout, [21]
tissue affinities for, [157]
variations in acute gout, [108]
variations in chronic gout, [109]
Wollaston’s researches on, [8]
Uric-acidæmia, [295]
Uricæmia and gout, [125]
in gout, [133]
in nephritis, [120]
not cause, but result, of gout, [148]
not necessarily due to renal defect, [123]
not peculiar to nephritis, [124]
significance of, [145]
tophi in relation to, [155]
Uricase, [87], [104]
absence of, in man, [104]
Uricolysis, [104]
Uricolytic enzyme, [105]
ferment, absence or diminution of, [106]
Urine, alkapton in, [59]
analysis of, in metabolism of gout, [113]
in treatment of gout, [337]
children’s, creatine in, [68]
cystin in, [59]
effects of guaiacum resin on, [405]
examination of, in diagnosis of articular gout, [250]
gouty, glyoxylic acid in, [65]
human, daily excretion of uric acid, amount of, [83]
scanty, before paroxysm of gout, [205]
Urosin in treatment of acute gout, [383]
Vaccine therapy in treatment of gout, [331]
Vapour baths, [428]
Vegetable cells, nucleic acid derived from, [98]
Vegetables in diet of gouty, [348]
Veins, engorged, before paroxysm of gout, [205]
Venesection, [4]
gout following, [178]
Vichy bath, [428]
Vidal’s atrophic form of arthritis deformans, [18]
Vinegar in diet of gouty, [350]
Viscera, functional capacity of, tests of, [338]
Visceral organs, tendency to fibrosis in gout, [186]
Vitamines, [340]
Volumetric method of determination of uric acid in blood (Curtman and Lehrman), [134]
Vomiting in acute paroxysms of gout, [333]
Wade’s theory of nervous origin of gout, [32]
Water, hot, advantages of, [360]
value of, as beverage in gout, [359]
“Water-soluble B,” [340]
“Water-soluble C,” [340]
Watson’s (Chalmers) researches on gout, [107], [172]
Weir-Mitchell method in reduction of obesity, [357]
Whisky in gout, [364], [370]
Wines as beverages in gout, [364]
general rules, [367]
individual and, [365]
importance of quality of, [366]
Wollaston’s researches on uric acid, [8]
Wrist, site of primary attack of gout, [267]
Xanthine, [75], [77]
Xanthine-oxidase, [99]
Xanthosine-hydrolase, [102]
X-ray examination of alimentary tract in treatment of gout, [336]
Yeast, nucleic acid derived from, [98]

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