MR. IVAN TOURGUENEFF.

In answer to your enquiry I have to state that I have no personal experience of the influence of tobacco and alcohol on the mind, as I do not smoke or use alcoholic drinks. My observations on other people lead me to the conclusion that tobacco is generally a bad thing, and that alcohol taken in very small quantities can produce a good effect in some cases of constitutional debility.

Iv. TOURGUENEFF.
March 14, 1882.