REFERENCES
[1] McCurdy: American Journal of Physiology, 1901, v, p. 98.
[2] Kaufmann: Archives de Physiologie, 1892, xxiv, p. 283.
[3] Ranke: Archiv für Anatomie, 1863, p. 446.
[4] Panella: Archives Italiennes de Biologie, 1907, xlviii, p. 462.
[5] Oliver and Schäfer: Journal of Physiology, 1895, xviii, p. 240.
CHAPTER VIII
THE SPECIFIC RÔLE OF ADRENIN IN COUNTERACTING THE EFFECTS OF FATIGUE
As a muscle approaches its fatigue level, its contractions are decreased in height. Higher contractions will again be elicited if the stimulus is increased. Although these phenomena are well known, no adequate analysis of their causes has been advanced. A number of factors are probably operative in decreasing the height of contraction: (1) The using up of available energy-producing material; (2) the accumulation of metabolites in the fatigued muscle; (3) polarization of the nerve at the point of repeated electrical stimulation; and (4) a decrease of irritability. It may be that there are interactions between these factors within the muscle, e. g., the second may cause the fourth.