Palsy — Mange
11th February, 1835
. — A Persian bitch, at the Zoological Gardens, who was well yesterday, now staggers as she walks, and has nearly lost the use of her hind legs. Gave a good dose of the castor-oil mixture.
18th
. She is materially worse and drags her hind legs after her. I would fain put on a charge, but the keeper does not like that her beautiful coat should be spoiled, and wishes to try what gentle exercise will do. She certainly, after she has been coaxed a great deal, will get on her legs and stagger on fifty yards or more. Gave the castor-oil mixture daily.
19th.
She is a little stronger, and walks a little better. Continue the mixture. Embrocate well with the rheumatic mixture — sp. tereb., sp. camph., liq. ammon., et tinct. opii — and give gentle exercise.
2d March.
— She does improve, although slowly; the charge is therefore postponed. Continue treatment.
30th.
She is considerably better. Continue the mixture, and use the embrocation every second day.
10th April
— She has mange in the bend of her arm, and on her chest. Use the sulphur ointment and alterative balls, and omit the embrocation and mixture. In less than a week she nearly recovered from her lameness, and ran about almost as well as ever.
30th.
She runs about very fairly, but the mange has assumed that character of scurvy which I do not know how to grapple with. Continue the alterative balls, and the ointment.
18th May.
— The mange has disappeared, but the palsy is returning; she staggers slightly, and droops behind. Give the castor-oil mixture and use the embrocation.
14th June.
— Mange quite gone, but palsy continues to a very considerable degree. I want to use the plaster; but the keeper pleads for a little delay. Continue the treatment.
1st July.
— I have at length determined to have recourse to the charge. A piece of thick sheep's leather was fitted lo her loins and haunches.
18th.
She appears to be improving, but it is very slowly.
31st.
Very little change. The plaster keeps on well: she has no power over her hind limbs; but she eats and drinks as well as ever.
23d August.
— No change. Give her half a grain of strychnia, morning and night.
26th
That singular secretion of milk, to which the bitch is subject nine weeks after œstrum, is now appearing. Her mammæ are enlarged, and I can squeeze a considerable quantity of milk out of the teats. Give an aloetic pill, and continue the strychnia.
31st
. The secretion of milk continues. There is slight enlargement and some heat of the mammæ; but she feeds as well as ever. Increase the dose of strychnia to three-quarters of a grain.
On the following day she was found dead. In making the usual longitudinal incision through the integuments of the abdomen a considerable quantity of milky fluid, mingled with blood, followed the knife. There was very slight enlargement of the teats, but intense inflammation of the whole of the mammary substance. The
omentum
, and particularly the portion opposite to the external disease, was also inflamed. Besides this there was not a vestige of disease.
This is an interesting case and deserves record. I fear that justice was not done to the animal at the commencement of the paralytic affection. In nineteen cases out of twenty in the dog, the constant but mild stimulus of a charge over the lumbar and sacral regions removes the deeper-seated inflammation of the spinal cord or its membranes, when the palsy is confined to the hind extremities, and has not been sufficiently long established to produce serious change of structure. The charge should have been applied at first. The almost total disappearance of the palsy during the cutaneous disease, which was attended with more than usual inflammation of the integument, is an instructive illustration of the power of counter-irritation, and of what might possibly have been effected in the first case; for much time was lost before the application of the charge, and when at length it was applied, it and the strychnia were powerless.
I consider the following case as exceedingly valuable, at least with reference to the power of strychnia in removing palsy:
19th August, 1836
. — A fine Alpine dog was suddenly attacked with a strange nervous affection. He was continually staggering about and falling. His head was forcibly bent backward and a little on one side, almost to his shoulder. A pound of blood was abstracted, a seton inserted from ear to ear, and eight grains of calomel administered.
21st
. He has perfectly lost the use of every limb. He has also amaurosis. perfect blindness, which had not appeared the day before. He hears perfectly, and he eats, and with appetite, when the food is put into his mouth. Gave him two large spoonfuls of the castor-oil mixture daily; this consists of three parts of castor-oil, two of syrup of buck-thorn, and one of syrup of white poppies.
23d
. A little better; can lift his head and throw it upon his side, and will still eat when fed. Continue the mixture, and give half a grain of strychnia daily.
24th
. Little change.
27th
. No change, except that he is rapidly losing flesh. Continue the treatment.
31th
. The strychnia increased to three-fourths of a grain morning and night. The castor-oil mixture continued in its full quantity. He was fed well, but there was a sunken, vacant expression of countenance.
2d September.
— He can move his head a little, and has some slight motion in his limbs.
4th.
He can almost get up. He recognises me for the first time. His appetite, which was never much impaired, has returned: this is to be attributed to strychnia, or the seton, or the daily aperient mixture. They have all, perhaps, been serviceable, but I attribute most to the strychnia; for I have rarely, indeed, seen any dog recover from such an attack. Continue the treatment.
6th.
Fast recovering. Medicine as before.
14th.
Improving, but not so fast as before. Still continue the treatment.
28th.
Going on slowly, but satisfactorily. Remove the seton, but continue the other treatment.
13th October.
— Quite well.
[Contents]/[Detailed Contents, p. 4]/[Index]
[Chapter VII — Rabies]
We are now arrived at one of the most important subjects in veterinary pathology. In other cases the comfort and the existence of our quadruped patients are alone or chiefly involved, but here the lives of our employers, and our own too, are at stake, and may be easily, and too often are, compromised. Here also, however other portions of the chain may be overlooked or denied, we have the link which most of all connects the veterinary surgeon with the practitioner of human medicine; or, rather, here is the circumscribed but valued spot where the veterinary surgeon has the vantage-ground.
In describing the nature, and cause and treatment of rabies, it will be most natural to take the animal in which it oftenest appears, by which it is most frequently propagated; the time at which the danger commences, and the usual period before the death of the patient.
years ago a dog, naturally ferocious, bit a child at Lisson Grove. The child, to all appearance previously well, died on the third day, and an inquest was to be held on the body in the evening. The Coroner ordered the dog to be sent to me for examination The animal was, contrary to his usual habit, perfectly tractable. This will appear to be of some importance hereafter. I examined him carefully. No suspicious circumstance could be found about him. There was no appearance of rabies. In the mean time the inquest took place, and the corpse of the child was carefully examined. One medical gentleman thought that there were some suspicious appearances about the stomach, and another believed that there was congestion of the brain.
The owner of the dog begged that the animal might not be taken from him, but might accompany him home. He took him home and destroyed him that no experiments might be made.
With great difficulty we procured the carcass, and from some inflammatory appearances about the tongue and the stomach, and the presence of a small portion of indigestible matter in the stomach, we were unanimously of opinion that the dog was rabid.
I do not mean to say that the child died hydrophobous, or that its death was accelerated by the nascent disease existing in the dog. There was probably some nervous affection that hastened the death of the infant, and the dog bit the child at the very period when the malady first began to develop itself. On the following day there were morbid lesions enough to prove beyond doubt that he was rabid.
This case is introduced because I used afterwards to accompany every examination of supposed or doubtful rabies with greater caution than I probably had previously used.
It is occasionally very difficult to detect the existence of rabies in its nascent state. In the year 1813, a child attempted to rob a dog of its morning food, and the animal resisting the theft, the child was slightly scratched by its teeth. No one dreamed of danger.
Eight days afterwards
symptoms of rabies appeared in the dog, the malady ran its course, and the animal died. A few days afterwards the child sickened — undoubted characteristics of rabies were observed — they ran their course and the infant was lost.
There are other cases — fortunately not numerous — in the records of human surgery, resembling this. A person has been bitten by a dog, he has paid little or no attention to it, and no application of the caustic has been made. Some weeks, or even months, have passed, he has nearly or quite forgotten the affair, when he becomes languid and feverish, and full of fearful apprehensions, and this appearing perhaps during several days, or more than a week. The empoisonment has then ceased to be a local affair, the virus has entered into the circulation, and its impression is made on the constitution generally. Fortunately the disposition to bite rarely develops itself until the full establishment of the disease, otherwise we might sometimes inquire whether it were not our duty to exterminate the whole race of dogs.
The following case deserves to be recorded. On the 21st of October, 1813, a dog was brought to me for examination. He had vomited a considerable quantity of coagulated blood. I happened to be particularly busy at the moment, and not observing anything peculiar in his countenance or manner, I ordered some astringent sedative medicine, and said that I would see him again in the afternoon.
In the course of the afternoon he was again brought. The vomiting had quite ceased. His mouth seemed to be swollen, and, on examining him, I found that some of his incisor teeth, both in the upper and lower jaw, had been torn out. This somewhat alarmed me; and, on inquiring of the servant, I was told that he suspected that they had had thieves about the house on the preceding night, for the dog had torn away the side of his kennel in attempting to get at them. I scolded him for not having told me of this in the morning; and then, talking of various things, in order to prolong the time and to be able closely to watch my patient, I saw, or thought I saw, but in a very slight degree, that the animal was tracing the fancied path of some imaginary object. I was then truly alarmed, and more especially since I had discovered that in the giving of the physic in the morning the man's hand had been scratched; a youth had suffered the dog to lick his sore finger, and the animal had also been observed to lick the sore ear of an infant. He was a remarkably affectionate dog, and was accustomed to this abominable and inexcusable nonsense.
I insisted on detaining the dog, and gave the man a letter to the surgeon, telling him all my fears. He promptly acted on the hint, and before evening, the proper means were taken with regard to all three.
I watched this dog day after day. He would not eat, but he drank a great deal more water than I liked. The surgeon was evidently beginning to doubt whether I was not wrong, but he could not dispute the occasional wandering of the eye, and the frequent spume upon the water. On the 26th of October, however, the sixth day after his arrival, we both of us heard the rabid howl burst from him: he did not, however, die until the 30th. I mention this as another instance of the great difficulty there is to determine the real nature of the case in an early stage of the disease.
M. Perquin relates an interesting case. A lady had a greyhound, nine years old, that was accustomed to lie upon her bed at night, and cover himself with the bed-clothes. She remarked, one morning, that he had torn the covering of his bed, and, although he ate but little, drank oftener, and in larger quantity, than he was accustomed to do. She led him to a veterinary surgeon, who assured her that there was nothing serious the matter. On the following day, he bit her fore-finger near the nail, as she was giving him something to eat. She led him again to the veterinary surgeon, who assured her that she needed not to be under the least alarm, and as for the little wound on her finger, it was of no consequence. On the following day, the 27th of December, the dog died. He had not ceased to drink most abundantly to the very last.
On the 4th of February, as the lady was dining with her husband, she found some difficulty in deglutition. She wished to take some wine, but was unable to swallow it.
On the 5th, she consulted a surgeon. He wished her to swallow a little soup in his presence. She attempted to do it, but could not accomplish her object after many an effort. She then fell into a state of violent agitation, with constriction of the pharynx, and the discharge of a viscid fluid from the mouth.
On the 7th, she died, four days after the first attack of the disease, and in a state of excessive loss of flesh.
can be no doubt that both the dog and his mistress died rabid, the former having communicated the disease to the latter; but there is no satisfactory account of the manner in which the dog became diseased
.
Joseph Delmaire, of Looberghe, twenty-nine years old, was, on the 6th of October, 1836, bitten in the hand by a dog that he met with in the forest, and that was evidently rabid. On the following morning, he went to a medical man of some repute in the country, who washed the wound, and scarified it, and terminated the operation by tracing a bloody cross on the forehead of the patient.
He returned home, but he was far from being satisfied. The image of the dog that had attacked him was always before him, and his sleep was troubled with the most frightful dreams. So passed four-and-twenty days, when Delmaire, rising from his bed, felt the most dreadful trepidation; he panted violently; it seemed as if an enormous weight oppressed his chest, and from time to time there was profound sighing and sobbing. He complained every moment that he was smothered. He attempted to drink, but it was with great difficulty that a few drops of barley-water were swallowed. His mouth was dry, his throat burning, his thirst excessive, and all that he attempted to swallow was rejected with horror.
At nine o'clock at night he was largely bled. His respiration was more free, but the dread of every fluid remained. After an hour's repose, he started and felt the most fearful pain in every limb — his whole body was agitated with violent convulsions. The former place of bleeding was reopened, and a great quantity of blood escaped. The pulse became small and accelerated. The countenance was dreadful — the eyes were starting from their sockets — he continually sprung from his seat and uttered the most fearful howling. A quantity of foam filled his mouth, and compelled a continued expectoration. In his violent fits, the strength of six men was not sufficient to keep him on his bed. In the midst of a sudden recess of fury he would disengage himself from all that were attempting to hold him, and dash himself on the floor; there, freed from all control, he rolled about, beat himself, and tore everything that he could reach. In the short intervals that separated these crises, he regained possession of his reasoning powers: he begged his old father to pardon him, he talked to him and to those around with the most intense affection, and it was only when he felt that a new attack was at hand, that he prayed them to leave him. At length his mental excitation began to subside; his strength was worn out, and he suffered himself to be placed on his bed. The horrible convulsions from time to time returned, but the dread of liquors had ceased. He demanded something to drink. They gave him a little white wine, but he was unable to swallow it; it was returned through his nostrils. The poor fellow then endeavoured to sleep; but it was soon perceived that he had ceased to live.
early symptoms of rabies in the dog are occasionally very obscure. In the greater number of cases, these are sullenness, fidgetiness, and continual shifting of posture. Where I have had opportunity, I have generally found these circumstances in regular succession. For several consecutive hours perhaps he retreats to his basket or his bed. He shows no disposition to bite, and he answers the call upon him laggardly. He is curled up and his face is buried between his paws and his breast. At length he begins to be fidgety. He searches out new resting-places; but he very soon changes them for others. He takes again to his own bed; but he is continually shifting his posture. He begins to gaze strangely about him as he lies on his bed. His countenance is clouded and suspicious. He comes to one and another of the family and he fixes on them a steadfast gaze as if he would read their very thoughts. "I feel strangely ill," he seems to say: "have you anything to do with it? or you? or you?" Has not a dog mind enough for this? If we have observed a rabid dog at the commencement of the disease, we have seen this to the very life.
There is a species of dog — the small French poodle — the essence of whose character and constitution is fidgetiness or perpetual motion.
If this dog has been bitten, and rabies is about to establish itself, he is the most irritative restless being that can be conceived of; starting convulsively at the slightest sound; disposing of his bed in every direction, seeking out one retreat after another in order to rest his wearied frame, but quiet only for a moment in any one, and the motion of his limbs frequently stimulating chorea and even epilepsy.
A peculiar delirium is an early symptom, and one that will never deceive. A young man had been bitten by one of his dogs; I was requested to meet a medical gentleman on the subject: I was a little behind my time; as I entered the room I found the dog eagerly devouring a pan of sopped bread. "There is no madness here," said the gentleman. He had scarcely spoken, when in a moment the dog quitted the sop, and, with a furious bark sprung against the wall as if he would seize some imaginary object that he fancied was there. "Did you see that?" was my reply. "What do you think of it?" "I see nothing in it," was his retort: "the dog heard some noise on the other side of the wall." At my serious urging, however, he consented to excise the part. I procured a poor worthless cur, and got him bitten by this dog, and carried the disease from this dog to the third victim: they all became rabid one after the other, and there my experiment ended. The serious matter under consideration, perhaps, justified me in going so far as I did.
This kind of delirium is of frequent occurrence in the human patient.
account given by Dr. Bardsley of one of his patients is very appropriate to on profit purpose:
"I observed that he frequently fixed his eyes with horror and affright on some ideal object, and then, with a sudden and violent emotion, buried his head beneath the bed-clothes. The next time I saw him repeat this action, I was induced to inquire into the cause of his terror. He asked whether I had not heard howlings and scratchings. On being answered in the negative, he suddenly threw himself on his knees, extending his arms in a defensive posture, and forcibly threw back his head and body. The muscles of the face were agitated by various spasmodic contractions; his eye-balls glazed, and seemed ready to start from their sockets; and, at the moment, when crying out in an agonizing tone, 'Do you not see that black dog?' his countenance and attitude exhibited the most dreadful picture of complicated horror, distress, and rage that words can describe or imagination paint."
I have again and again seen the rabid dog start up after a momentary quietude, with unmingled ferocity depicted on his countenance, and plunge with a savage howl to the end of his chain. At other times he would stop and watch the nails in the partition of the stable in which he was confined, and fancying them to move he would dart at them, and occasionally sadly bruise and injure himself from being no longer able to measure the distance of the object. In one of his sudden fits of violence a rabid dog strangled the Cardinal Crescence, the Legate of the Pope, at the Council of Trent in 1532.
M. Magendie has often injected into the veins of an hydrophobous dog as much as five grains of opium without producing any effect; while a single grain given to the healthy dog would suffice to send him almost to sleep.
of Mr. Babington's patients thought that there was a cloud of flies about him. "Why do you not kill those flies!" he would cry; and then he would strike at them with his hand, and shrink under the bed-clothes, in the most dreadful fear.
There is also in the human being a peculiarity in this delirium which seems to distinguish it from every other kind of mental aberration.
"The patient," in Mr. Lawrence's language, "is pursued by a thousand phantoms that intrude themselves upon his mind; he holds conversation with imaginary persons; he fancies himself surrounded with difficulties, and in the greatest distress. These thoughts seem to pass through his mind with wonderful rapidity, and to keep him in a state of the greatest distress, unless he is quickly spoken to or addressed by his name, and, then, in a moment the charm is broken; every phantom of imagination disappears, and at once he begins to talk as calmly and as connectedly as in perfect health."
So it is with the dog, whether he is watching the motes that are floating in the air, or the insects that are annoying him on the walls, or the foes that he fancies are threatening him on every side — one word recalls him in a moment. Dispersed by the magic influence of his master's voice, every object of terror disappears, and he crawls towards him with the same peculiar expression of attachment that used to characterize him.
Then comes a moment's pause — a moment of actual vacuity — the eye slowly closes, the head droops, and he seems as if his fore feet were giving way, and he would fall: but he springs up again, every object of terror once more surrounds him — he gazes wildly around — he snaps — he barks, and he rushes to the extent of his chain, prepared to meet his imaginary foe.
The expression of the countenance of the dog undergoes a considerable change, principally dependent on the previous disposition of the animal. If he was naturally of an affectionate disposition, there will be an anxious, inquiring countenance, eloquent, beyond the power of resisting its influence. It is made up of strange suppositions as to the nature of the depression of mind under which he labours, mingled with some passing doubts, and they are but passing, as to the concern which the master has in the affair; but, most of all, there is an affectionate and confiding appeal for relief. At the same time we observe some strange fancy, evidently passing through his mind, unalloyed, however, by the slightest portion of ferocity.
the countenance of the naturally savage brute, or him that has been trained to be savage, there is indeed a fearful change; sometimes the conjunctiva is highly injected; at other times it is scarcely affected, but the eyes have an unusually bright and dazzling appearance. They are like two balls of fire, and there is a peculiar transparency of the hyaloid membrane, or injection of that of the retina.
A very early symptom of rabies in the dog, is an extreme degree of restlessness. Frequently, he is almost invariably wandering about, shifting from corner to corner, or continually rising up and lying down, changing his posture in every possible way, disposing of his bed with his paws, shaking it with his mouth, bringing it to a heap, on which he carefully lays his chest, or rather the pit of his stomach, and then rising up and bundling every portion of it out of the kennel. If he is put into a closed basket, he will not be still for an instant, but turn round and round without ceasing. If he is at liberty, he will seem to imagine that something is lost, and he will eagerly search round the room, and particularly every corner of it, with strange violence and indecision.
In a very great portion of cases of hydrophobia in the human being, there is, as a precursory symptom, uneasiness, pain, or itching of the bitten part. A red line may also be traced up the limb, in the direction of the lymphatics. In a few cases the wound opens afresh.
The poison is now beginning fatally to act on the tissue, on which it had previously lain harmless. When the conversation has turned on this subject, long after the bitten part has been excised, pain has darted along the limb. I have been bitten much oftener than I liked, by dogs decidedly rabid, but, proper means being taken, I have escaped; and yet often, when I have been over-fatigued, or a little out of temper, some of the old sores have itched and throbbed, and actually become red and swollen.
dog appears to suffer a great deal of pain in the ear in common canker. He will be almost incessantly scratching it, crying piteously while thus employed. The ear is, oftener than any other part, bitten by the rabid dog, and, when a wound in the ear, inflicted by a rabid dog, begins to become painful, the agony appears to be of the intensest kind. The dog rubs his ear against every projecting body, he scratches it might and main, and tumbles over and over while he is thus employed.
The young practitioner should be on his guard there. Is this dreadful itching a thing of yesterday, or, has the dog been subject to canker, increasing for a considerable period? Canker both internal and external is a disease of slow growth, and must have been long neglected before it will torment the patient in the manner that I have described. The question as to the length of time that an animal has thus suffered will usually be a sufficient guide.
The mode in which he expresses his torture will serve as another direction. He will often scratch violently enough when he has canker, but he will not roll over and over like a football except he is rabid. If there is very considerable inflammation of the lining membrane of the ear, and engorgement and ulceration of it, this is the effect of canker; but if there is only a slight redness of the membrane, or no redness at all, and yet the dog is incessantly and violently scratching himself, it is too likely that rabies is at hand.
In the early stage of rabies, the attachment of the dog towards his owner seems to be rapidly increased, and the expression of that feeling. He is employed, almost without ceasing, licking the hands, or face, or any part he can get at. Females, and men too, are occasionally apt to permit the dog, when in health, to indulge this filthy and very dangerous habit with regard to them. The virus, generated under the influence of rabies, is occasionally deposited on a wounded or abraded surface, and in process of time produces a similar disease in the person that has been so inoculated by it. Therefore it is that the surgeon so anxiously inquires of the person that has been bitten, and of all those to whom the dog has had access, "Has he been accustomed to lick you? have you any sore places about you that can by possibility have been licked by him?" If there are, the person is in fully as much danger as if he had been bitten, and it is quite as necessary to destroy the part with which the virus may have come in contact. A lady once lost her life by suffering her dog to lick a pimple on her chin.
is a beautiful species of dog, often the inhabitant of the gentleman's stable — the Dalmatian or coach dog. He has, perhaps, less affection for the human species than any other dog, except the greyhound and the bull-dog; he has less sagacity than most others, and certainly less courage. He is attached to the stable; he is the friend of the horse; they live under the same roof; they share the same bed; and, when the horse is summoned to his work, the dog accompanies every step. They are certainly beautiful dogs, and it is pleasing to see the thousand expressions of friendship between them and the horse; but, in their continual excursions through the streets, they are exposed to some danger, and particularly to that of being bitten by rabid dogs. It is a fearful business when this takes place. The coachman probably did not see the affray; no suspicion has been excited. The horse rubs his muzzle to the dog, and the dog licks the face of the horse, and in a great number of cases the disease is communicated from the one to the other. The dog in process of time dies, the horse does not long survive, and, frequently too, the coachman shares their fate. I have known at least twenty horses destroyed in this way.
A depraved appetite is a frequent attendant on rabies in the dog. He refuses his usual food; he frequently turns from it with an evident expression of disgust; at other times, he seizes it with greater or less avidity, and then drops it, sometimes from disgust, at other times because he is unable to complete the mastication of it. This palsy of the organs of mastication, and dropping of the food, after it has been partly chewed, is a symptom on which implicit confidence may be placed.
Some dogs vomit once or twice in the early period of the disease: when this happens, they never return to the natural food of the dog, but are eager for everything that is filthy and horrible. The natural appetite generally fails entirely, and to it succeeds a strangely depraved one. The dog usually occupies himself with gathering every little bit of thread, and it is curious to observe with what eagerness and method he sets to work, and how completely he effects his object. He then attacks every kind of dirt and filth, horse-dung, his own dung, and human excrement. Some breeds of spaniels are very filthy feeders without its being connected with disease, but the rabid dog eagerly selects the excrement of the horse, and his own. Some considerable care, however, must be exercised here. At the period of dentition, and likewise at the commencement of the sexual affection, the stomach of the dog, and particularly that of the bitch, sympathises with, or shares in, the irritability of the gums, and of the constitution generally, and there is a considerably perverted appetite. The dog also feels the same propensity that influences the child, that of taking hard substances into the mouth, and seemingly trying to masticate them. Their pressure on the gums facilitates the passage of the new teeth. A young dog will, therefore, be observed gathering up hard substances, and, if he should chance to die, a not inconsiderable collection of them is sometimes found in the stomach. They are, however, of a peculiar character; they consist of small pieces of bone, slick, and coal.
The contents of the stomach of the rabid dog, are often, or generally, of a most filthy description. Some hair or straw is usually found, but the greater part is composed of horse-dung, or of his own dung, and it may be received as a certainly, that if he is found deliberately devouring it, he is rabid.
Some very important conclusions may be drawn from the appearance and character of the urine. The dog, and at particular times when he is more than usually salacious, may, and does diligently search the urining places; he may even, at those periods, be seen to lick the spot which another has just wetted; but, if a peculiar eagerness accompanies this strange employment, if, in the parlour, which is rarely disgraced by this evacuation, every corner is perseveringly examined, and licked with unwearied and unceasing industry, that dog cannot be too carefully watched, there is great danger about him; he may, without any other symptom, be pronounced to be decidedly rabid. I never knew a single mistake about this.
has been said of the profuse discharge of saliva from the mouth of the rabid dog. It is an undoubted fact that, in this disease, all the glands concerned in the secretion of saliva, become increased in bulk and vascularity. The sublingual glands wear an evident character of inflammation; but it never equals the increased discharge that accompanies epilepsy, or nausea. The frothy spume at the corners of the mouth, is not for a moment to be compared with that which is evident enough in both of these affections. It is a symptom of short duration, and seldom lasts longer than twelve hours. The stories that are told of the mad dog covered with froth, are altogether fabulous. The dog recovering from, or attacked by a fit, may be seen in this state; but not the rabid dog. Fits are often mistaken for rabies, and hence the delusion.
The increased secretion of saliva soon passes away. It lessens in quantity; it becomes thicker, viscid, adhesive, and glutinous. It clings to the corners of the mouth, and probably more annoyingly so to the membrane of the fauces. The human being is sadly distressed by it, he forces it out with the greatest violence, or utters the falsely supposed bark of a dog, in his attempts to force it from his mouth. This symptom occurs in the human being, when the disease is fully established, or at a late period of it. The dog furiously attempts to detach it with his paws.
It is an early symptom in the dog, and it can scarcely be mistaken in him. When he is fighting with his paws at the corners of his mouth, let no one suppose that a bone is sticking between the poor fellow's teeth; nor should any useless and dangerous effort be made to relieve him. If all this uneasiness arose from a bone in the mouth, the mouth would continue permanently open instead of closing when the animal for a moment discontinues his efforts. If after a while he loses his balance and tumbles over, there can be no longer any mistake. It is the saliva becoming more and more glutinous, irritating the fauces and threatening suffocation.
To this naturally and rapidly succeeds an insatiable thirst. The dog that still has full power over the muscles of his jaws continues lo lap. He knows not when to cease, while the poor fellow labouring under the dumb madness, presently to be described, and whose jaw and tongue are paralysed, plunges his muzzle into the water-dish to his very eyes, in order that he may get one drop of water into the back part of his mouth to moisten and to cool his dry and parched fauces. Hence, instead of this disease being always characterised by the dread of water in the dog, it is marked by a thirst often perfectly unquenchable. Twenty years ago, this assertion would have been peremptorily denied. Even at the present day we occasionally meet with those who ought to know better, and who will not believe that the dog which fairly, or perhaps eagerly, drinks, can be rabid.
[January] 22d
, 1815. — A Newfoundland dog belonging to a gentleman in Piccadilly was supposed to have swallowed a penny-piece on the 20th. On the evening of that day he was dull, refused his food, and would not follow his master.
21st
. He became restless and pouting, and continually shifting his position. He would not eat nor would he drink water, but followed his mistress into her bed-room, which he had never done before, and eagerly lapped the urine from her chamber-pot. He was afterwards seen lapping his own urine. His restlessness and panting increased, He would neither eat nor drink, and made two or three attempts to vomit.
22d
. He was brought to me this evening. His eyes were wild, the conjunctiva considerably inflamed, and he panted quickly and violently. There was a considerable flow of saliva from the corners of his mouth. He was extremely restless and did not remain in one position half a minute. There was an occasional convulsive nodding motion of the head. The eyes were wandering, and evidently following some imaginary object; but he was quickly recalled from his delirium by my voice or that of his master. In a few moments, however, he was wandering again. He had previously been under my care, and immediately recognised me and offered me his paw. His bark was changed and had a slight mixture of the howl, and there was a husky choking noise in the throat.
I immediately declared that he was rabid, and with some reluctance on the part of his master, he was left with me.
23d
, 8 A. M. The breathing was less quick and laborious. The spasm of the head was no longer visible. The flow of saliva had stopped and there was less delirium. The jaw began to be dependent: the rattling, choking noise in his throat louder. He carried straw about in his mouth. He picked up some pieces of old leather that lay within his reach and carefully concealed them under his bed. Two minutes afterwards he would take them out again, and look at them, and once more hide them. He frequently voided his urine in small quantities, but no longer lapped it. A little dog was lowered into the den, but he took no notice of it.
10 P. M. Every symptom of fever returned with increased violence. He panted very much, and did not remain in the same posture two seconds. He was continually running to the end of his chain and attempting to bite. He was eagerly and wildly watching some imaginary object. His voice was hoarser — more of the howl mixing with it. The lips were distorted, and the tongue very black. He was evidently getting weaker. After two or three attempts to escape, he would sit down for a second, and then rise and plunge to the end of his chain. He drank frequently, yet but little at a time, and that without difficulty or spasm.
12 P. M. The thirst strangely increased. He had drunk or spilled full three quarts of water. There was a peculiar eagerness in his manner. He plunged his nose to the very bottom of his pan, and then snapped at the bubbles which he raised. No spasm followed the drinking. He took two or three pieces from my hand, but immediately dropped them from want of power to hold them. Yet he was able for a moment suddenly to close his jaws. When not drinking he was barking with a harsh sound, and frequently started suddenly, watching, and catching at some imaginary object.
24th
, A. M. He was more furious, yet weaker. The thirst was insatiable. He was otherwise diligently employed in shattering and tearing everything within his reach. He died about three o'clock.
It is impossible to say what was the origin of this disease in him. It is not connected with any degree or variation of temperature, or any particular state of the atmosphere. It is certainly more frequent in the summer or the beginning of autumn than in the winter or spring, because it is a highly nervous and febrile disease, and the degree of fever, and irritability, and ferocity, and consequent mischief are augmented by increase of temperature. In the great majority of cases, the inoculation can be distinctly proved. In very few can the possibility be denied. The injury is inflicted in an instant. There is no contest, and before the injured party can prepare to retaliate, the rabid dog is far away.
It can easily be believed that when a favourite dog has, but for a moment, lagged behind, he may be bitten without the owner's knowledge or suspicion. A spaniel belonging to a lady became rabid. The dog was her companion in her grounds at her country residence, and it was rarely out of her sight except for a few minutes in the morning, when the servant took it out. She was not conscious of its having been bitten, and the servant stoutly denied it. The animal died. A few weeks afterwards the footman was taken ill. He was hydrophobous. In one of his intervals of comparative quietude he confessed that, one morning, his charge had been attacked and rolled over by another dog; that there was no appearance of its having been bitten, but that it had been made sadly dirty, and he had washed it before he suffered it again to go into the drawing-room. The dog that attacked it must have been rabid, and some of his saliva must have remained about the coat of the spaniel, by which the servant was fatally inoculated.
case of this fearful disease must not be passed over. A dog that had been docile and attached to his master and mistress, was missing one morning, and came home in the evening almost covered with dirt. He slunk to his basket, and would pay no attention to any one. His owners thought it rather strange, and I was sent for in the morning. He was lying on the lap of his mistress, but was frequently shifting his posture, and every now and then he started, as if he heard some strange sound. I immediately told them what was the matter, and besought them to place him in another and secure room. He had been licking both their hands. I was compelled to tell them at once what was the nature of the case, and besought them to send at once for their surgeon. They were perfectly angry at my nonsense, as they called it, and I took my leave, but went immediately to their medical man, and told him what was the real state of the case. He called, as it were accidentally, a little while afterwards, and I was not far behind him. The surgeon did his duty, and they escaped.
May, 1820, I attended on a bitch at Pimlico. She had snapped at the owner, bitten the man-servant and several dogs, was eagerly watching imaginary objects, and had the peculiar rabid howl. I offered her water. She started back with a strange expression of horror, and fell into violent convulsions that lasted about a minute. This was repeated a little while afterwards, and with the same result. She was destroyed.
The horrible spasms of the human being at the sight of, or the attempt to swallow, fluids occur sufficiently often to prove the identity of the disease in the biped and the quadruped; but not in one in fifty cases is there, in the dog, the slightest reluctance to liquids, or difficulty in swallowing them.
almost every case in which the dog utters any sound during the disease, there is a manifest change of voice. In the dog labouring under ferocious madness, it is perfectly characteristic. There is no other sound that it resembles. The animal is generally standing, or occasionally sitting, when the singular sound is heard. The muzzle is always elevated. The commencement is that of a perfect bark, ending abruptly and very singularly, in a howl, a fifth, sixth, or eighth higher than at the commencement. Dogs are often enough heard howling, but in this case it is the perfect bark, and the perfect howl rapidly succeeding to the bark.
Every sound uttered by the rabid dog is more or less changed. The huntsman, who knows the voice of every dog in his pack, occasionally hears a strange challenge. He immediately finds out that dog, and puts him, as quickly as possible, under confinement. Two or three days may pass over, and there is not another suspicious circumstance about the animal; still he keeps him under quarantine, for long experience has taught him to listen to that warning. At length the disease is manifest in its most fearful form.
There is another partial change of voice, to which the ear of the practitioner will, by degrees, become habituated, and which will indicate a change in the state of the animal quite as dangerous as the dismal howl; I mean when there is a hoarse inward bark, with a slight but characteristic elevation of the tone. In other cases, after two or three distinct barks, will come the peculiar one mingled with the howl. Both of them will terminate fatally, and in both of them the rabid howl cannot possibly be mistaken.
There is a singular brightness in the eye of the rabid dog, but it does not last more than two or three days. It then becomes dull and wasted; a cloudiness steals over the conjunctiva, which changes to a yellow tinge, and then to a dark green, indicative of ulceration deeply seated within the eye. In eight and forty hours from the first clouding of the eye, it becomes one disorganised mass.
There is in the rabid dog a strange embarrassment of general sensibility — a seemingly total loss of feeling.
Absence of pain in the bitten part is an almost invariable accompaniment of rabies. I have known a dog set to work, and gnaw and tear the flesh completely away from his legs and feet. At other times the penis is perfectly demolished from the very base. Ellis in his
Shepherd's Sure Guide
, asserts, that, however severely a mad dog is beaten, a cry is never forced from him. I am certain of the truth of this, for I have again and again failed in extracting that cry. Ellis tells that at the kennel at Goddesden, some of the grooms heated a poker red hot, and holding it near the mad hound's mouth, he most greedily seized it, and kept it until the mouth was most dreadfully burned.
In the great majority of cases of furious madness, and in almost every case of dumb madness, there is evident affection of the lumbar portion of the spinal cord. There is a staggering gait, not indicative of general weakness, but referable to the hind quarters alone, and indicating an affection of the lumbar motor nerve. In a few cases it approaches more to a general paralytic affection.
In the very earliest period of rabies, the person accustomed to dogs will detect the existence of the disease.
The animal follows the flight, as has been already stated, of various imaginary objects. I have often watched the changing countenance of the rabid dog when he has been lost to every surrounding object. I have seen the brightening countenance and the wagging tail as some pleasing vision has passed before him; but, oftener has the countenance indicated the mingled dislike and fear with which the intruder was regarded. As soon as the phantom came within the proper distance he darted on it with true rabid violence.
A
, seemingly at play, snapped, in the morning, at the feet of several persons. In the evening he bit his master, his master's friend, and another dog. The old habits of obedience and affection then returned. His master, most strangely, did not suspect the truth, and brought the animal to me to be examined. The animal was, as I had often seen him, perfectly docile and eager to be caressed. At my suggestion, or rather entreaty, he was left with me. On the following morning the disease was plain enough, and on the following day he died. A
post-mortem
examination took place, and proved that he was unequivocally rabid.
A
would nurse her dog, after I had declared it to be rabid, and when he was dangerous to every one but herself, and even to her from the saliva which he plentifully scattered about. At length he darted at every one that entered the room, until a footman keeping the animal at bay with the poker, the husband of the lady dragged her from the room. The noise that the dog made was then terrific, and he almost gnawed his way through the door. At midnight his violence nearly ceased, and the door was partially opened. He was staggering and falling about, with every limb violently agitated. At the entreaty of the lady, a servant ventured in to make a kind of bed for him. The dog suddenly darted at him, and dropped and died.
A
, ten years old, had been ill, and refused all food for three days. On the fourth day he bit a cat of which he had been unusually fond, and he likewise bit three dogs. I was requested to see him. I found him loose in the kitchen, and at first refused to go in, but, after observing him for a minute or two, I thought that I might venture. He had a peculiarly wild and eager look, and turned sharply round at the least noise. He often watched the flight of some imaginary object, and pursued with the utmost fury every fly that he saw. He searchingly sniffed about the room, and examined my legs with an eagerness that made me absolutely tremble. His quarrel with the cat had been made up, and when he was not otherwise employed he was eagerly licking her and her kittens. In the excess or derangement of his fondness, he fairly rolled them from one end of the kitchen to another. With difficulty I induced his master to permit me to destroy him.
is not every dog, that in the most aggravated state of the disease shows a disposition to bite. The finest Newfoundland dog that I ever saw became rabid. He had been bitten by a cur, and was supposed to have been thoroughly examined in the country. No wound, however, was found: the circumstance was almost forgotten, and he came up to the metropolis with his master. He became dull, disinclined to play, and refused all food. He was continually watching imaginary objects, but he did not snap at them. There was no howl, nor any disposition to bite. He offered himself to be caressed, and he was not satisfied except he was shaken by the paw. On the second day I saw him. He watched every passing object with peculiar anxiety, and followed with deep attention the motions of a horse, his old acquaintance; but he made no effort to escape, nor evinced any disposition to do mischief. I went to him, and patted and coaxed him, and he told me as plainly as looks and actions, and a somewhat deepened whine could express it, how much he was gratified. I saw him on the third day. He was evidently dying. He could not crawl even to the door of his temporary kennel; but he pushed forward his paw a little way, and, as I shook it, I felt the tetanic muscular action which accompanies the departure of life.
On the other hand there are rabid dogs whose ferocity knows no bounds. If they are threatened with a stick, they fly at, and seize it, and furiously shake it. They are incessantly employed in darting to the end of their chain, and attempting to crush it with their teeth, and tearing to pieces their kennel, or the wood work that is within their reach. They are regardless of pain. The canine teeth, the incisor teeth are torn away; yet, unwearied and insensible to suffering, they continue their efforts to escape. A dog was chained near a kitchen fire. He was incessant in his endeavours to escape, and, when he found that he could not effect it, he seized, in his impotent rage, the burning coals as they fell, and crushed them with his teeth.
If by chance a dog in this state effects his escape, he wanders over the country bent on destruction. He attacks both the quadruped and the biped. He seeks the village street, or the more crowded one of the town, and he suffers no dog to escape him. The horse is his frequent prey, and the human being is not always safe from his attack. A
dog running down Park-lane, in 1825, bit no fewer than five horses, and fully as many dogs. He was seen to steal treacherously upon some of his victims, and inflict the fatal wound. Sometimes he seeks the more distant pasturage. He gets among the sheep, and more than forty have been fatally inoculated in one night. A rabid dog attacked a herd of cows, and five-and-twenty of them fell victims. In July, 1813, a mad dog broke into the menagerie of the Duchess of York, at Oatlands, and although the palisades that divided the different compartments of the menagerie were full six feet in height, and difficult, or apparently almost impossible to climb, he was found asleep in one of them, and it was clearly ascertained that he had bitten at least ten of the dogs.
At length the rabid dog becomes completely exhausted, and slowly reels along the road with his tail depressed, seemingly half unconscious of surrounding objects. His open mouth, and protruding and blackened tongue, and rolling gait sufficiently characterise him. He creeps into some sheltered place and then he sleeps twelve hours or more. It is dangerous to disturb his slumbers, for his desire to do mischief immediately returns, and the slightest touch, or attempt to caress him, is repaid by a fatal wound. This should be a caution never to meddle with a sleeping dog in a way-side house, and, indeed, never to disturb him anywhere.
In an early period of the disease in some dogs, and in others when the strength of the animal is nearly worn away, a peculiar paralysis of the muscles of the tongue and jaws is seen. The mouth is partially open, and the tongue protruding. In some cases the dog is able to close his mouth by a sudden and violent effort, and is as ferocious and as dangerous as one the muscles of whose face are unaffected. At other times the palsy is complete, and the animal is unable to close his mouth or retract his tongue. These latter cases, however, are rare.
A dog must not be immediately condemned because he has this open mouth and fixed jaw. Bones constitute a frequent and a considerable portion of the food of dogs. In the eagerness with which these bones are crushed, spicula or large pieces of them become wedged between the molar teeth, and form an inseparable obstacle to the closing of the teeth. The tongue partially protrudes. There is a constant discharge of saliva from the mouth, far greater than when the true paralysis exists. The dog is continually fighting at the corners of his mouth, and the countenance is expressive of intense anxiety, although not of the same irritable character as in rabies.
I was once requested to meet a medical gentleman in consultation respecting a supposed case of rabies. There was protrusion and discoloration of the tongue, and fighting at the corners of the mouth, and intense anxiety of countenance. He had been in this state for four-and-twenty hours. This was a case in which I should possibly have been deceived had it been the first dog that I had seen with dumb madness. After having tested a little the ferocity or manageableness of the animal, I passed my hand along the outside of the jaws, and felt a bone wedged between two of the grinders. The forceps soon set all right with him.
It is
to inquire more strictly into the
post-mortem
appearances of rabies in the dog.
In dumb madness the unfailing accompaniment is, to a greater or less degree, paralysis of the muscles of the lower jaw, and the tongue is discoloured and swollen, and hanging from the mouth; more blood than usual also is deposited in the anterior and inferior portion of it. Its colour varies from a dark red to a dingy purple, or almost black. In ferocious madness it is usually torn and bruised, or it is discoloured by the dirt and filth with which it has been brought into contact, and, not unfrequently, its anterior portion is coated with some disgusting matter. The papillæ, or small projections on the back of the tongue, are elongated and widened, and their mucous covering evidently reddened. The orifices of the glands of the tongue are frequently enlarged, particularly as they run their course along the frœnum of the tongue.
The fauces, situated at the posterior part of the mouth, generally exhibit traces of inflammation. They appear in the majority of cases of ferocious madness, and they are never deficient after dumb madness. They are usually most intense either towards the palatine arch or the larynx. Sometimes an inflammatory character is diffused through its whole extent, but occasionally it is more or less intense towards one or both of the terminations of the fauces, while the intermediate portion retains nearly its healthy hue.
There is one circumstance of not unfrequent occurrence, which will at once decide the case — the presence of indigestible matter, probably small in quantity, in the back part of the mouth. This speaks volumes as to the depraved appetite of the patient, and the loss of power in the muscles of the pharynx.
Little will depend on the tonsils of the throat. They occasionally enlarge to more than double their usual size; but this is more in quiet than in ferocious madness. The insatiable thirst of the rabid dog is perhaps connected with this condition of them.
The epiglottis should be very carefully observed. It is more or less injected in every case of rabies. Numerous vessels increase in size and multiply round its edge, and there is considerable injection and thickening.
Inflammation of the edges of the glottis, and particularly of the membrane which covers its margin, is often seen, and accounts for the harsh guttural breathing which frequently accompanies dumb madness. The inflammatory blush of the larynx, though often existing in a very slight degree, deserves considerable attention.
The appearances in the trachea are very uncertain. There is occasionally the greatest intensity of inflammation through the whole of it; at other times there is not the slightest appearance of it. There is the same uncertainty with regard to the bronchial tubes and the lungs; but there is no characteristic symptom or lesion in the lungs.
Great stress has been laid on the appearance of the heart; but, generally speaking, in nine cases out of ten, the heart of the rabid dog will exhibit no other symptoms of disease than an increased yet variable deepness of colour in the lining membrane of the ventricles. No dependence can be placed on any of the appearances of the œsophagus; and, when they are at the worst, the inflammation occupies only a portion of that tube.
With regard to the interior of the stomach, if the dog has been dead only a few hours the true inflammatory blush will remain. If four-and-twenty hours have elapsed, the bright red colour will have changed to a darker red, or a violet or a brownish hue. In a few hours after this, a process of corrosion will generally commence, and the mucous membrane will be softened and rendered thinner, and, to a certain extent, eaten through. The examiner, however, must not attribute that to disease which is the natural process of the cession of life.
Much attention should be paid to the appearance of the stomach and its contents. If it contains a strange mingled mass of hair, and hay, and straw, and horse-dung, and earth, or portions of the bed on which the dog had lain, we should seldom err if we affirmed that he died rabid; for it is only under the influence of the depraved appetite of rabies that such substances are devoured. It is not the presence of every kind of extraneous substance that will be satisfactory: pieces of coal, or wood, or even the filthiest matter, will not justify us in pronouncing the animal to be rabid; it is that peculiarly mingled mass of straw, and hair, and filth of various kinds, that must indicate the existence of rabies.
When there are no solid indigesta, but a fluid composed principally of vitiated bile or extravasated blood, there will be a strong indication of the presence of rabies. When, also, there are in the duodenum and jejunum small portions of indigesta, the detection of the least quantity will be decisive. The remainder has been ejected by vomit; and inquiry should be made of the nature of the matter that has been discharged.
inflammation of rabies is of a peculiar character in the stomach. It is generally confined to the summits of the folds of the stomach, or it is most intense there. On the summits of the rugæ there are effusions of bloody matter, or spots of ecchymosis, presenting an appearance almost like crushed black currants. There may be only a few of them; but they are indications of the evil that has been effected.
From appearances that present themselves in the intestines, the bladder, the blood-vessels, or the brain, no conclusion can be drawn; they are simply indications of inflammation.
now rapidly, and for a little while, retrace our steps. What is the cause of this fatal disease, that has so long occupied our attention? It is the saliva of a rabid animal received into a wound, or on an abraded surface. In horses, cattle, sheep, swine, and the human being, it is caused by inoculation alone; but, according to some persons, it is produced spontaneously in other animals.
I will suppose that a wound by a rabid dog is inflicted. The virus is deposited on or near its surface, and there it remains for a certain indefinite period of time. The wound generally heals up kindly; in fact, it differs in no respect from a similar wound inflicted by the teeth of an animal in perfect health. Weeks and months, in some cases, pass on, and there is nothing to indicate danger, until a degree of itching in the cicatrix of the wound is felt. From its long-continued presence as a foreign body, it may have rendered the tissue, or nervous fibre connected with it, irritable and susceptible of impression, or it may have attracted and assimilated to itself certain elements, and rabies is produced.
The virus does not appear to have the same effect on every animal. Of four dogs bitten by, or inoculated from, one that is rabid, three, perhaps, would display every symptom of the disease. Of four human beings, not more than one would become rabid. John Hunter used to say not more than one in twenty; but that is probably erroneous. Cattle appear to have a greater chance of escape, and sheep a still greater chance.
The
of incubation is different in different animals. With regard to the human being, there are various strange and contradictory stories. Some have asserted that it has appeared on the very day on which the bite was inflicted, or within two or three days of that time. Dr. Bardsley, on the other hand, relates a case in which twelve years elapsed between the bite and the disease. If the virus may lurk so long as this in the constitution, it is a most lamentable affair. According to one account, more than thirty years intervened. The usual time extends from three weeks to six or seven months.
In the dog I have never seen a case in which plain and palpable rabies occurred in less than fourteen days after the bite. The average time I should calculate at five or six weeks. In three months I should consider the animal as tolerably safe. I am, however, relating my own experience, and have known but two instances in which the period much exceeded three months. In one of these five months elapsed, and the other did not become affected until after the expiration of the seventh month.
The quality and the quantity of the virus may have something to do with this, and so may the predisposition in the bitten animal to be affected by the poison. If it is connected with œstrum, the bitch will probably become a disgusting, as well as dangerous animal; if with parturition, there is a strange perversion of maternal affection — she is incessantly and violently licking her young, continually shifting them from place to place; and, in less than four-and-twenty hours, they will be destroyed by the reckless manner in which they are treated. In both cases the development of the disease seems to wait on the completion of her time of pregnancy. It appears in the space of two months after the bite, if her parturition is near at hand, or it is delayed for double that time, if the period of labour is so far distant.
The duration of the disease is different in different animals. In man it has run its course in twenty-four hours, and rarely exceeds seventy-two. In the horse from three to four days; in the sheep and ox from five to seven; and in the dog from four to six.
Of
real nature of the rabid virus, we know but little. It has never been analysed, and it would be a difficult process to analyse it. It is not diffused by the air, nor communicated by the breath, nor even by actual contact, if the skin is sound. It must be received into a wound. It must come in contact with some tissue or nervous fibre, and lie dormant there for a considerable, but uncertain period. The absorbents remove everything around; whatever else is useless, or would he injurious, is taken away, but this strange substance is unchanged. It does not enter into the circulation, for there it would undergo some modification and change, or would be rejected. It lies for a time absolutely dormant, and far longer than any other known poison; but, at length, the tissue on which it has lain begins to render it somewhat sensible, and assimilates to itself certain elements. The cicatrix begins to be painful, and inflammation spreads around. The absorbents are called into more powerful action; they begin to attack the virus itself, and a portion of it is taken up, and carried into the circulation, and acquires the property of assimilating other secretions to its own nature, or it is determined to one of the secretions only; it alters the character of that secretion, envenoms it, and gives it the power of propagating the disease.
Something like this is the history of many animal poisons. In variola and the vaccine disease the poison is determined to the skin, in glanders to the Schneiderian membrane, and in farcy to the superficial absorbents. Each in its turn becomes the depôt of the poison. So it is with the salivary glands of the rabid animal; in them it is formed, or to them it is determined, and from them, and them alone, it is communicated to other animals.
Dick, in his valuable
Manual of Veterinary Science
, states some peculiar views, and those highly interesting, respecting the disease of rabies. He holds it to be essentially an inflammatory affection, attacking peculiarly the mucous membrane of the nose, and extending thence through the cribriform plate of the ethmoid bones to the interior part of the brain, and so giving rise to a derangement of the nervous system as a necessary consequence. This train of symptoms constitutes mainly, if not wholly, the essence of an occasional epidemic not unlike some forms of influenza or epizootic disease, and the bite of a rabid animal is not always, to an animal so bitten, the exciting cause of the disease, but merely an accidental concomitant in the prevailing disorder. Also the disease hydrophobia, produced in man, is not always the result of any poison introduced into his system, but merely the melancholy, and often fatal result of panic fear, and of the disordered slate of the imagination. Those who are acquainted with the effects of sympathy, and imitation, and panic, in the production of nervous disorders, will readily apprehend the meaning of the Professor.
Some of these diseases speedily run their course and exhaust themselves. Cowpox and farcy, in many instances, have this character. Perhaps, to a certain degree, this may be affirmed of all of them. I have seen cases, which I could not mistake, in which the symptoms of rabies were one after another developed. The dog was plainly and undeniably rabid, and I had given him up as lost; but, after a certain period, the symptoms began to be less distinct; they gradually disappeared, and the animal returned to perfect health. This may have formed one ground of belief in the power of certain medicines, and most assuredly it gives encouragement to perseverance in the use of remedial measures.
It has then been proved, and I hope demonstratively, that rabies is propagated by inoculation. It has also been established that although every animal labouring under this disease is capable of communicating it, yet, with very few exceptions, it can be traced to the bite of the dog.
has still further been shown that the malady, generally appears at some period between the third and seventh month from the time of inoculation. At the expiration of the eighth month, the animal may be considered to be safe; for there is only one acknowledged case on record, in which the disease appeared in the dog after the seventh month from the bite had passed.
it would appear that if a species of quarantine could be established, and every dog confined separately for eight months, the disease would be annihilated in our country, or could only reappear in consequence of the importation of some infected animal. Such a course of proceeding, however, could never be enforced either in the sporting world or among the peasantry. Other measures, however, might be resorted to in order to lessen the devastations of this malady; and that which first presents itself to the mind as a powerful cause of rabies is the number of useless and dangerous dogs that are kept in the country for the most nefarious and, in the neighbourhood of considerable towns, the most brutal purposes; without the slightest hesitation, I will affirm that rabies is propagated, nineteen times out of twenty, by the cur and the lurcher in the country, and the fighting-dog in towns.
A tax should be laid on every useless dog, and doubly or trebly heavier than on the sporting-dog. No dog except the shepherd's should be exempt from this tax, unless, perhaps, it is the truck-dog, and his owner should be compelled to take out a license; to have his name in large letters on his cart; and he should be heavily fined if the animal is found loose in the streets, or if he is used for fighting.
The disease is rarely propagated by petted and house-dogs They are little exposed to the danger of inoculation; yet, we pity, or almost detest, the folly of those by whom their favourites are indulged, and spoiled even more than their children.
will now suppose that a person has had the misfortune to be bitten by a rabid dog: what course is he to pursue? What preventive means are to be adopted? Some persons, and of no mean standing in the medical world, have recommended a ligature. The reply would be, that this ligature must be worn during a very inconvenient and dangerous period of time. The virus lies in the wound inert during many successive weeks and months.
. Haygarth first suggested that a long-continued stream of warm water should be poured upon the wound from the mouth of a kettle. He says that the poison exists in a fluid form, and therefore we should suppose that water would be its natural solvent. Dr. Massey adds to this, that if the wound is small, it should be dilated, in order that the stream may descend on the part on which the poison is deposited. We are far, however, from being certain that this falling of water on the part, may not by possibility force a portion of the virus farther into the texture, or cause it to be entangled with other parts of the wound
.
There is a similar or stronger objection to the cupping-glass of Dr. Barry. The virus, forced from the texture with which it lies in contact by the rush of blood from the substance beneath, is too likely to inoculate, or become entangled with, other parts of the wound.
There is great objection to suction of the wound; for, in addition to this possible entanglement, the lips, or the mouth, may have been abraded, and thus the danger considerably aggravated. There also remains the undecided question as to the absorption of the virus through the medium of a mucous surface.
Excision of the part is the mode of prevention usually adopted by the human surgeon, and to a certain extent it is a judicious practice. If the virus is not received into the circulation, but lies dormant in the wound for a considerable time, the disease cannot supervene if the inoculated part is destroyed.
This operation, however, demands greater skill and tact than is generally supposed. It requires a determination fully to accomplish the desired object; for every portion of the wound with which the tooth could possibly have come into contact, must be removed. This is often exceedingly difficult to accomplish, on account of the situation and direction of the wound. The knife must not enter the wound, or it will be likely to be itself empoisoned, and then the mischief and the danger will be increased instead of removed. Dr. Massey was convinced of the impropriety of this when he advised that,
"should the knife by chance enter the wound that had been made by the dog's tooth, the operation should be recommenced with a clean knife, otherwise the sound parts will become inoculated."
If the incision is made freely and properly round the wound, and does not penetrate into it, yet the blood will follow the knife, and a portion of it will enter into the wound caused by the dog, and will come in contact with the virus, and will probably be contaminated, and will then overflow the original wound, and will be received into the new incision, and will carry with it the seeds of disease and death: therefore it is, that scarcely a year passes without some lamentable instances of the failure of incisions. It has occurred in the practice of the most eminent surgeons, and seems scarcely or not all to impeach the skill of the operator.
Aware of this, there are very few human practitioners who do not use the caustic after the knife. Every portion of the new wound is submitted to its influence. They do not consider the patient to be safe without this second operation. But has the question never occurred to them, that if the caustic is necessary to give security to the operation by incision, the knife might have been spared, and the caustic alone used?
The veterinary surgeon, when operating on the horse, or cattle, or the dog, frequently has recourse to the actual cautery. I could, perhaps, excuse this practice, although I would not adopt it, in superficial wounds; but I do not know the instrument that could be safely used in deeper ones. If it were sufficiently small to adapt itself to the tortuous course of little wounds, it would be cooled and inert before it could have destroyed the lower portions of them. If it were of sufficient substance long to retain the heat, it would make a large and fearful chasm, and probably interfere with the future usefulness of the animal. The result of the cases in which the cautery has been used proves that in too many instances it is an inefficient protection. The rabid dog in Park Lane has already been mentioned. He bit several horses before he could be destroyed. Caustic was applied to one of them, and the hot iron to the others. The first was saved, almost all the others were lost. A similar case occurred last spring; the caustic was an efficacious preventive; the cautery was perfectly useless. What caustic then should be applied? Certainly not that to which the surgeon usually has recourse — a liquid one. Certainly not one that speedily deliquesces; for they are both unmanageable, and, what is a more important consideration, they may hold in solution, and not decompose the poison, and thus inoculate the whole of the wound.
application which promises to be successful, is that of the
lunar caustic
. It is perfectly manageable, and, being sharpened to a point, may be applied with certainty to every recess and sinuosity of the wound.
Potash and nitric acid form a caustic which will destroy the substances with which they come in contact, but the combination of this caustic and the animal fibre will be a soft or semi-fluid mass. In this the virus is suspended, and with this it lies or may be precipitated upon the living fibre beneath. Then there is danger of re-inoculation; and it would seem that this fatal process is often accomplished. The eschar formed by the lunar caustic is dry, hard, and insoluble. If the whole of the wound has been fairly exposed to its action, an insoluble compound of animal fibre and the metallic salt is produced, in which the virus is wrapped up, and from which it cannot be separated. In a short time the dead matter sloughs away, and the virus is thrown off with it.
Previous to applying the caustic it will sometimes be necessary to enlarge the wound, in order that every part may be fairly got at; and the eschar having sloughed off, it will always be prudent to apply the caustic a second time, but more slightly, in order to destroy any part that may not have received the full influence of the first operation, or that, by possibility, might have been inoculated during the operation.
Mr. Smerdon, in the
Medical and Physical Journal
, March 1820, thus reasons:
"All the morbid poisons that require to lie dormant a certain time before their effects are manifested, pass into the system through the medium of the absorbents," (we somewhat differ from Mr. Smerdon here, but his reasoning is equally applicable to the nervous system,) "and if the absorbents are excited, their action is increased. I am satisfied that even in a venereal sore the application of a caustic, instead of destroying the disease, causes its rapid extension. Then," asks he, "if the virus on a small venereal sore is rendered more active by the caustic, is it not highly probable that the same law holds good with respect to the poison of rabies?"
The sooner the caustic is applied the better; but I should not hesitate to have recourse to it even after the constitution has become affected. It is
in the
Medico-Chirurgical Annals
of Altenburg (Sept. 1821), that two men were bitten by a rabid dog. One became hydrophobous and died; the other had evident symptoms of hydrophobia a few days afterwards. A surgeon excised the bitten part, and the disease disappeared. After a period of six days the symptoms returned. The wound was examined; considerable fungus was found sprouting from its bottom. This was extirpated. The hydrophobia symptoms were again removed, and the man did well. This is a most instructive case.
In
Journal Pratique de Médecine Vétérinaire
, M. Damalix gives an interesting account of the effect of a bite of a rabid dog on a horse. On the 8th of July, 1828, a fowl-merchant, proceeding to the market of Colmar, was attacked by a dog, who, after some fruitless efforts to get into the cart, bit the horse on the left side of the face, and fled precipitately. A veterinary surgeon was sent for, who applied the cautery to the horse, gave him some populeum ointment, and bled him. Everything appeared to go on well, and on the 16th the wounds were healed.
On the 25th a great alteration took place. The horse was careless and slow; he sometimes refused to go at all, and would not attend in the least to the whip, which had never occurred before. In the evening the wounds opened spontaneously, an ichorous and infectious pus run from them; there was salivation and utter loss of appetite: strange fancies seemed to possess him; he showed a desire to bite his master. The veterinary surgeon might approach him with safety; but the moment his owner or the children appeared, he darted at them, and would have torn them in pieces. The disease now took on the appearance of acute glanders; livid and fungous wounds broke out; the stable was saturated with an infectious smell, the horse refused his food, or was unable to eat. The mayor at last interfered, and the animal was destroyed. In the
Treatises on The Horse, Cattle, and Sheep
, in former volumes, accounts are fully given of this dreadful malady in these animals. It may not be uninteresting to give a hasty sketch of it in some of the inferior classes.
[Rabies] in the Rabbit.
— I very much regret that I never instituted a course of experiments on the production and treatment of rabies in this animal. It would have been attended with little expense or danger, and some important discoveries might have been made. Mr. Earle, in a case in which he was much interested, inoculated two rabbits with the saliva of a dog that had died rabid. They were punctured at the root of the ears. One of the rabbits speedily became inflamed about the ears, and the ears were paralysed in both rabbits. The head swelled very much, and extensive inflammation took place around the part where the virus was inserted. One of them died without exhibiting any of the usual symptoms of the disease; the other, after a long convalescence, survived, and eventually recovered the use of his ears. Mr. Earle very properly doubted whether this was a case of rabies.
Dr. Capello describes, but in not so satisfactory a manner as could be wished, a case of supposed rabies in one of these animals. A rabbit and a dog lived together in a family. They were strange associates; but such friendships are not unfrequent among animals. The dog became rabid, and died. A man bitten by that dog became hydrophobous, and died. No one dreamed of the rabbit being in danger, and he ran about the house as usual; but, one day, he found his way to the chamber of the mistress of the house, with a great deal of viscid saliva running from his mouth, furiously attacked her, and left the marks of his violence on her leg. He then ran into a neighbouring stable, and bit the hind-legs of a horse several times. Finally, he retreated to a corner of the stable, and was there found dead. Neither the lady nor the horse eventually suffered.
[Rabies] in the Guinea-pig
. — A man suspected of being hydrophobous was taken to the Middlesex Hospital. He was examined before several of the medical students; one of whom, in order to make more sure of the affair, inoculated a guinea-pig with the saliva taken from the man's mouth. The guinea-pig had been usually very playful, and fond of being noticed; but, on the eleventh day after this inoculation, he began to be dull and sullen, retiring into his house, and hiding himself as much as he could in a corner. On the following day he became out of temper, and even ferocious in his way; he bit at everything that was presented to him, gnawed his cage, and made the most determined efforts to escape. Once or twice his violence induced convulsions of his whole frame; and they might be produced at pleasure by dashing a little water at him. In the course of the night following he died.
[Rabies] in the Cat
. — Fortunately for us, this does not often occur; for a mad cat is a truly ferocious animal. I have seen two cases, one of them to my cost; yet, I am unable to give any satisfactory account of the progress of the disease. The first stage seems to be one of sullenness, and which would probably last to death; but from that sullenness it is dangerous to rouse the animal. It probably would not, except in the paroxysm of rage, attack any one; but during that paroxysm it knows no fear, nor has its ferocity any bounds.
A cat, that had been the inhabitant of a nursery, and the playmate of the children, had all at once become sullen and ill-tempered. It had taken refuge in an upper room, and could not be coaxed from the corner in which it had crouched. It was nearly dark when I went. I saw the horrible glare of her eyes, but I could not see so much of her as I wished, and I said that I would call again in the morning.
I found the patient, on the following day, precisely in the same situation and the same attitude, crouched up in a corner, and ready to spring. I was very much interested in the case; and as I wanted to study the countenance of this demon, for she looked like one, I was foolishly, inexcusably imprudent. I went on my hands and knees, and brought my face nearly on a level with hers, and gazed on those glaring eyes, and that horrible countenance, until I seemed to feel the deathly influence of a spell stealing over me. I was not afraid, but every mental and bodily power was in a manner suspended. My countenance, perhaps, alarmed her, for she sprang on me, fastened herself on my face, and bit through both my lips. She then darted down stairs, and, I believe, was never seen again. I always have nitrate of silver in my pocket, even now I am never without it; I washed myself, and applied the caustic with some severity to the wound; and my medical adviser and valued friend, Mr. Millington, punished me still more after I got home. My object was attained, although at somewhat too much cost, for the expression of that brute's countenance will never be forgotten.
The later symptoms of rabies in this animal, no one, perhaps, has had the opportunity of observing: we witness only the sullenness and the ferocity.
[Rabies] in the Fowl
. — Dr. Ashburner and Mr. King inoculated a hen with the saliva from a rabid cow. They made two incisions through the integument, under the wings, and then well rubbed into these cuts the foam taken from the cow's mouth. She was after this let loose among other fowls in the poultry-yard. The incisions soon healed, and their places could with difficulty be discovered. Ten weeks passed over, when she was observed to refuse her food, and to run at the other fowls. She had a strange wild appearance, and her eyes were blood-shot. Early on the following morning her legs became contracted, so that she very soon lost the power of standing upright. She remained sitting a long time, with the legs rigid, refusing food and water, and appearing very irritable when touched. She died in the evening, immediately after drinking a large quantity of water which had been offered to her.
[Rabies] in the Badger
. — Hufeland, in his valuable
Journal of Practical Medicine
, relates a case of a rabid female badger attacking two boys. She bit them both, but she fastened on the thigh of one of them, and was destroyed in the act of sucking his blood. The poor fellow died hydrophobous, but the other escaped. This fact, certainly, gives us no idea of the general character of the disease in this animal; but it speaks volumes as to its ferocity.
[Rabies] in the Wolf
. — Rabies is ushered in by nearly the same symptoms, and pursues the same course in the wolf us in the dog, with this difference, which would be readily expected, that his ferocity and the mischief which he accomplishes are much greater. The dog hunts out his own species, and his fury is principally directed against them; although, if he meets with a flock of sheep, or a herd of cattle, he readily attacks them, and, perhaps, bites the greater part of them. The dog, however, frequently turns out of his way to avoid the human being, and seldom attacks him without provocation. The wolf, on the contrary, although he commits fearful ravages among the sheep and cattle, searches out the human being as his favorite prey. He conceals himself near the entrance to the village, and steals upon and wounds every passenger that he can get at. There are several accounts of more than twenty persons having been bitten by one wolf; and there is a fearful history of sixteen persons perishing from the bite of one of these animals. This is in perfect agreement with the account which I have given of the connexion between the previous temper and habits of the rabid dog, and the mischief that he effects under the influence of this malady. The wolf, as he wanders in the forest, regards the human being as his persecutor and foe; and, in the paroxysm of rabid fury, he is most eager to avenge himself on his natural enemy. Strange stories are told of the arts to which he has recourse in order to accomplish his purpose. In the great majority of cases he steals unawares upon his victim, and the mischief is effected before the wood-cutter or the villager is conscious of his danger.
following observations and experiments respecting rabies, by Dr. Hertwich, Professor at the Veterinary School at Berlin, are well worthy of attention.
- Out of fifty dogs that had been inoculated with virus taken from a rabid animal of the same species, fourteen only were infected.
- In the cases where inoculation had been practised without effect, no reason could be assigned why the disease should not have taken place. This consequently proves that the malady is similar to others of a contagious nature, and that there must exist a predisposition in the individual to receive the disease before it can occur. In one experiment, a mastiff dog, aged four years, was inoculated without exhibiting any symptoms of the malady, while seven others, who had been inoculated at the same time and place, soon became rabid. Several of these animals had been inoculated several times before any symptoms showed themselves, while in others, on the contrary, once was sufficient.
- It appears that in a state of doubtful rabies, one or two accidental or artificial inoculations are not sufficient to create a negative proof of its existence.
- This disease has never ben communicated to an individual from one infected by means of the perspirable matter; this, therefore, is a proof that the contagious part of the disease is not of a volatile nature.
- It does not only exist in the saliva and the mucus of the mouth, but likewise in the blood and the parenchyma of the salivary glands; but not in the pulpy substance of the nerves.
- The power of communicating infection is found to exist in all stages of the confirmed disease, even twenty-four hours after the decease of the rabid animal.
- The morbid virus, when administered internally, appears to be incapable of communicating this disease; inasmuch as of twenty dogs to whom was given a certain quantity, not one exhibited the least symptom of rabies.
- The application of the saliva upon recent wounds appears to have been as often succeeded by confirmed rabies as when the dog had been bitten by a rabid animal.
- It cannot now be doubled that the disease is produced by the wound itself, as was supposed by M. Girard of Lyons, not by the fright of the individual, according to the opinion of others, but only from the absorption of the morbid virus from its surface.
- Several experiments have proved to me the little reliance there is to be placed on the opinions of Baden and Capello, who believe that, in those dogs who become rabid after the bite of an animal previously attacked with this disease, the contagious properties of the saliva is not continued, but only exists in those primarily bitten.
- During the period of incubation of the virus there are no morbid, local, or general alterations of structure or function to be seen in the infected animal; neither are there any vesicles to be perceived on the inferior surface of the tongue, nor any previous symptoms which are found in other contagious diseases.
- [This] disease is generally at its height at the end of fifty days after either artificial or accidental inoculation; and the author has never known it to manifest itself at a later period.
- It is quite an erroneous idea to suppose that dogs in a state of health are enabled to distinguish, at first sight, a rabid animal, inasmuch as they never refuse their food when mixed with the secretions of those infected[3].
following singular trial respecting the death of a child by hydrophobia is worth quoting:
Jones v. Parry.
— The plaintiff is a labourer, who gets only fourteen shillings a week to support himself and his family. The defendant is his neighbour, and keeps a public-house. This was an action brought by the plaintiff to recover damages against the defendant for the loss of his son, who was bitten by the defendant's dog, and afterwards became affected with rabies, of which disease he died.
It appeared in the evidence that the defendant's dog had, some time ago, been bitten by another dog; in consequence of which this dog was tied in the cellar, but the length of the rope which was allowed him enabled him to go to a considerable distance. The plaintiff's child knew the dog, having often played with him when he was at large. Some time ago the child crossed the street, near to the place where the dog was fastened, who rushed out of the place in which he was confined to where the child stood, sprung upon him, and bit him sadly in the face, and afterwards violently shook him. The child being thus wounded, a surgeon was sent for, who, after having dressed him, and attended him for a certain time, gave directions that he should be taken to the sea-side, and bathed in the salt water.
This having been continued for some time, the child was brought home, and, at the expiration of a month from the day on which he was bitten, became evidently and strangely ill. The surgeon proved beyond all shadow of doubt thai the child laboured under rabies; that he had the never-failing symptoms of that dreadful affliction; and that a little while before he expired, he even barked like a dog. The surgeon's charge to the father for his attendance was
£1. 6s. 6d.
, which, together with the charge of the undertaker for the funeral of the child, amounted to between six and seven pounds. Application was made to the defendant to defray this expense, which at first he expressed a willingness to comply with, but afterwards refused; upon which this action was brought.
After some time the defendant offered to pay the plaintiff the sum of
£6. 3s. 6d.
, and the expense of the funeral and the surgeon, provided the plaintiff would bear the expenses of the lawsuit, which he was not in a condition to do, as probably it would amount to more than that money. On this account, therefore, the action was now brought into court. There was no proof that the defendant knew or suspected his dog to be mad, previously to his attacking the boy; but an animal known to have been bitten by a mad dog, ought either to have been at once destroyed, or so secured that it was impossible for him to do mischief.
Lord Kenyon observed to the jury, that this was one of those causes which came home to the feelings of all, yet must not be carried farther than justice demanded. A cause like this never, perhaps, before occurred in a court of justice; but there had been many resembling it in point of principle. If a dog, known to be ill-tempered and vicious, did any person an injury without provocation, there could be no question that the owner of the dog was answerable, in a court of justice, for the injury inflicted. Here was a worse case. The dog by whom the child was bitten had been attacked by another that was undeniably rabid. His master was aware of this, and placed him in a state of partial confinement — a confinement so lax, and so inefficient, that this poor child had broken through it, and was bitten and died. What other people would have done in such a situation he could not tell; but, if he were asked what he would do, he answered, he certainly would kill the dog, however much of a favourite he had been, because no atonement was within the reach of his fortune to make to the injured party for such a dreadful visitation of Providence as this. It was not enough for the owner of such a dog to say, he took precaution to prevent mischief: he ought to have made it impossible that mischief could happen; and, therefore, as soon as there was any reasonable suspicion that the dog was rabid, he ought to have destroyed him.
But, if the owner wished to save the animal, until he was satisfied of the actual state of the case, he ought to have secured him, so that every individual might be safe. Whether the defendant thought he had done all that was necessary, his lordship did not know; but this he knew, that the dog was not perfectly secured, otherwise this misfortune could not have happened.
The care which the defendant took in this case was not enough, and, therefore, he had no doubt that this action was maintainable. The jury would judge what damages they ought to give. He would refer this to their feelings. They could not avoid commiserating the distress of the family of this poor man. He should, however, observe to the jury, that they must not give vindictive damages; but still he did not think that damages merely to the amount of
£6
. or
£7
., which was stated to be the expense of the funeral, &c., would at all meet the justice of the case. He was inclined to advise them to go beyond that, although he did not plead vindictive damages. There would be costs to be defrayed by the plaintiff, well known in the profession under the head of "extra costs," even although he had a verdict. If the verdict had been at his disposal, he would have taken care that these costs should have been borne by the party that had been the cause of the injury. That appeared to him to be the justice of the case.
He trusted that none who heard him would doubt his sincerity, when he said, he lamented the misfortune which had given birth to this action; and, with that qualification of the case, he must say that he was not sorry that this action had been brought. He thanked the plaintiff for bringing it; for it might be of public benefit. It would teach a lesson that would not soon be forgotten, "That a person, who knowingly keeps a vicious, dangerous animal, should be considered to be answerable for all the acts of that animal." There were instances in which very large damages had been given to repair such injuries. He did not say that the present case called for large damages; but, if other cases of the same kind should be brought into court after this had been made public, he hoped the jury would go beyond the ordinary limits, and give verdicts which might operate
in terrorem
on the offending parties.
for the plaintiff — damages £36
.
child was bitten by a rabid dog at York, and became hydrophobous. All possibility of relief having vanished, the parents, desirous of putting an end to the agony of their child, or fearful of its doing mischief, smothered it between two pillows. They were tried for murder, and found guilty. They were afterwards pardoned; but the intention of the prosecutor was that of deterring others from a similar practice, in a like unfortunate situation
.
1821, a physician, at Poissy, was sentenced to pay 8000 francs (£320) to a poor widow whose husband died of hydrophobia, in consequence of a bite from the physician's dog, he knowing that the dog had been bitten, yet not confining him.
Our [author] having written so extensively upon the subject of rabies, it would seem superfluous in us to attempt to add anything more upon a subject so ably and practically handled by one having so great opportunities to make personal observations. However, to allay the feelings of many of our dogkilling citizens, we will not hesitate to assert that we do not place as much credence in the frequency of rabies as is generally done; but, on the other hand, are strongly led to believe that the accounts of this much-dreaded malady are greatly exaggerated both in this country and in England.
That there may be a few cases of rabies in our country in the course of a year, we do not doubt; but, at the same time, we are satisfied that the affection in its genuine form is quite rare, and that the great hue and cry made every season about mad dogs, is more the result of ignorance and fright than of reality.
Our limits in this publication would not allow us sufficient space to enlarge upon the many pathological questions naturally arising from a minute examination of this subject, more particularly as our views are somewhat at variance with the generally received opinion, and which, of course, we would be forced to express with considerable diffidence, owing to the impossibility of collecting such evidence as might seem necessary to substantiate any peculiar doctrine.
That tetanus, hysteria, and other spasmodic affections have often been mistaken for rabies, there is no doubt, and we can easily imagine the mental effect produced upon an individual of a highly nervous temperament, by the knowledge of his being bitten by an animal known to be hydrophobic; and we can, without difficulty, reconcile with our best judgment the belief that the workings of such an individual's imagination, occasioned by the never-ceasing dread of the horrid malady to which he is now exposed, might be sufficient to produce a train of symptoms somewhat resembling the actual state of rabies.
For the benefit of these nervous unfortunates, we might say to them, that the statistics of this affection show a very considerable ratio in favour of escape from inoculation when bitten, or of entire recovery even after the development of the disease, and that there are many other ills in the catalogue of medicine that they should take equal pains to provide against as lyssa canina. We doubt not that the minds of many will be relieved, when informed that John Hunter mentions an instance, in which, out of twenty persons bitten by a rabid dog, only one suffered from the malady; and that of fifty-nine dogs inoculated by Professor Hertwick at the veterinary school of Berlin, only fourteen were affected; and of eleven patients entrusted to the care of M. Blaise of Cluny, seven recovered after exhibiting greater or less degrees of spasmodic symptoms.
It [may] prove interesting to our readers, to insert in these pages an account of the first two cases of rabies known in Philadelphia, and as related to us by a venerable and much-esteemed citizen, who is well known in the scientific world as a gentleman of deep research, and we agree with him in opinion, that this much-dreaded disease is most frequently the result of like causes, or rather that like symptoms often induce the belief of the presence of this malady, when, in fact, no such disease does exist.
Towards the close of the last century, there lived a tailor in Front street, near Market, in the midst of the most respectable people of that period; among the number was our esteemed friend Mr. Hembel, as also Judge Tilghman. This tailor possessed an ill-tempered little spaniel, who, lounging about the street-door, attacked every one that passed by, snapping and snarling in the most worrisome manner, more particularly at every little urchin that invaded his "right of pavement," and not unfrequently biting them or tearing their clothes from their back. The owner of the dog was appealed to on many occasions by the neighbours, begging that the quarrelsome brute should either be disposed of or kept within doors. To all these solicitations and warnings the little tailor paid no heed, but continued stitching his breeches and cribbing his customers' goods, while the ugly little spaniel, without interruption, amused himself by snapping at and biting the heels of the passers-by.
The nuisance at last became insufferable, and Judge Tilghman applied to Mr. Hembel to assist him in getting rid of this troublesome brute; the latter gentleman advised the administration of a small quantity of strychnia, concealed in a portion of meat, which proposition was agreed upon and immediately carried into execution. A short time after the administering of this dose the spaniel sickened, and retired from his post to the kitchen, which was in the basement, and where an Irish domestic was engaged in washing; the dog appeared uneasy for a time, and suddenly, being taken with the involuntary muscular convulsions that so frequently follow the administration of this powerful drug, ran around the kitchen yelping and howling at a most terrible rate, and ultimately, to the no small discomfiture and amazement of the maid, sprang up into the wash-tub, at which unceremonious caper, on the part of the dog, the woman became greatly alarmed and ran out into the street, followed by the whole household, crying mad dog, which soon produced an uproar in the neighbourhood, no one daring to satisfy himself as to the correctness of the report, and all, perhaps, too ignorant of the subject to discern the real cause of the animal's singular behaviour. The tailor, still bearing a strong attachment to his unfortunate favourite, and being somewhat more daring than his neighbours, ventured, at length, to peep into the kitchen to see the state of affairs, and seeing the dog still convulsed and foaming at the mouth, was more than ever confirmed in the belief of hydrophobia, and knowing full well the biting propensities of the animal, independent of rabies, concluded, much to the relief of every one, to shoot him. The next step in the programme was the dragging out and consigning of the patient to a watery grave, which was accomplished by placing, with a pair of tongs, a noose over the head of the animal, and thus hauling him out of the basement window amid the cheers of the assembled populace who soon cast him into the Delaware.
The second case of rabies as related to us by Mr. Hembel was as follows: — In 1793 the barbers of the city were in the habit of going around to the various boarding-houses for the purpose of shaving the visitors in their apartments, instead of accommodating them, as at the present time, in their own establishments.
One of these knights of the razor, living also in Front street, when going to and from a fashionable boarding-house in the vicinity, was not unfrequently assailed by a small cur who often took him by the heels when hurrying along.
To get rid of this annoying little animal as speedily and secretly as possible, he had recourse to the powers of strychnia, which produced in a very short time similar effects upon the poor victim, and the result was another great hue and cry about mad dogs.
These authentic and remarkable cases of hydrophobia were heralded in all the papers of the day, which, from that time forward, were filled with notes of caution to all dog-owners.
Of the treatment of rabies we will make but a few remarks, as of the immense number of specifics proposed for this disease, amounting in all to several hundred, few or none can be relied on to the exclusion of the others; but those medicines, perhaps, known as opiates or anti-spasmodics, claim a larger share of attention than any others in combating the disease after its development. In [looking] over the very original works of Jacques Du Fouilloux, a worthy cynegetical writer of the sixteenth century, we find a prescription that was supposed by many to be an infallible specific for this disease, and as it appears to us quite as certain in its effects on the animal economy as many others of the inert substances that have been lauded to the skies both in our country and in other parts of the world as antidotes, we take the liberty of transcribing it, as also of adding a translation of his quaint French.
Autre recepte par mots preservants la rage.
'Ay appris vne recepte d'vn Gentil-homme, en Bretaigne, lequel faisoit de petits escriteaux, où n'y auoit seulement que deux lignes, lesquels il mettoit en vne omellette d'oeufs, puis les faisoit aualer aux chiens qui auorient esté mords de chiens enragez, et auoit dedans l'escriteau, Y Ran Quiran Cafram Cafratrem, Cafratrosque. Lesquels mots disoit estre singuliers pour empescher les chiens de la rage, mais quant à moi ie n'y adiouste pas foy.
I have learned a recipe from a nobleman of Brittany, which is composed of a written charm, in which there are only two lines; these he put in an omelet of eggs, he then made the dogs that had been bitten by a rabid animal swallow them. There was on the paper "Y Ran Quiran Cafram Cafratrem, Cafratrosque". These words were said to be singularly efficacious in preventing madness in dogs, but for my part I do not credit it.
Although our quaint author considered the above charm even too marvellous for his belief, we give below his own prescription in which he placed implicit confidence, but, no doubt, on trial it would prove "as singularly efficacious" as the other.
Baing pour lauer, les chiens, quand ils ont esté mords des chiens enragez, de peur qu'ils enragent.
Quand les chiens sont mords ou desbrayez de chiens enragez, il faut incontinent emplir vne pippe d'eau, puis prendre quatre boisseaux de sel et les ietter dedans, en meslaut fort le sel auec vn baston pour le faire fondre soudainement: et quand il sera fondu, faut mettre le chien dedans, et le plonger tout, sans qu'il paroisse rien, par neuf fois: puis quand il sera bien laué, faut le laisser aller, celà l'empeschera d'enrager.
When a dog has been bitten or scratched by another affected with madness, we must immediately take a tub of water and throw into it four bushels of salt, stirring it briskly with a stick to make it dissolve quickly. When the salt shall be dissolved, put the dog into the bath, and plunge him well nine times, so that the bath shall cover him each time; now that he is well washed you may let him go, as this will prevent his becoming rabid.
Having given publicity to the two preceding valuable receipts, we must be pardoned for adding our own views upon this point, as a caution to those who may not feel sufficient faith in the remedies above mentioned.
The wound should be thoroughly washed and cleansed as soon as possible after the bite is inflicted: no sucking of the parts, as is advised by many, for the purpose of extracting the poison, as the presence of a small abrasion of the lips or interior of the mouth would most assuredly subject the parts to inoculation. If the wound be ragged, the edges may be taken off with a pair of sharp scissors; the wound must then be thoroughly cauterized with nitrate of silver (lunar caustic), being sure to introduce the caustic into the very depths of the wound, so that it will reach every particle of poison that may have insinuated itself into the flesh. If the wound is too small to admit of the stick of caustic, it may be enlarged by the knife, taking care, however, not to carry the poison into the fresh cut, which can be avoided by wiping the knife at each incision. Should the wound be made on any of the limbs, a bandage may be placed around it during the application of these remedies, the more effectually to prevent the absorption of the virus. Nitrate of silver is a most powerful neutralizer of specific poisons, and the affected parts will soon come away with the slough, no dressings being necessary, except perhaps olive oil, if there should be much inflammation of the parts. If the above plan be pursued, the patient need be under no apprehension as to the result, but make his mind perfectly easy on the point. This is the course generally pursued by the veterinary surgeons of Europe, and there are but few of them who have not, some time in their practice, been bitten and often severely lacerated by rabid animals; nevertheless, we never hear of their having suffered any bad effects from such accidents. If caustic be not at hand, the wound may be seared over with red-hot iron, which will answer as good a purpose, although much more painful in its operation. Mr. Blaine, in closing his able and scientific article on this subject, very justly remarks,
"Would I could instil into such minds the uncertainty of the disease appearing at all; that is, even when no means have been used; and the perfect security they may feel who have submitted to the preventive treatment detailed. I have been bitten several times, Mr. Youatt several also; yet in neither of us was any dread occasioned: our experience taught us the absolute certainty of the preventive means; and such I take on me to pronounce they always prove, when performed with dexterity and judgment." We acknowledge ourselves a convert to this gentleman's doctrine; and feel satisfied that if the above course be adopted, there need be no fear whatever of the development of this frightful affection. — L
La Folie des Animaux
, by M. Perquin.
The physician Apollonius, having been bitten by a rabid dog, induced another dog to lick the wound,
"ut idem medicus esset qui vulneris auctor fuit."
Journal Pratique de Méd. Vét.
Sporting Magazine
, vol. xviii. p. 186.
Daniel's
Rural Sports
, vol. i. p. 220.
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[Chapter VIII — The Eye and its Diseases]
The diseases that attack the same organ are essentially different, in different animals, in their symptoms, intensity, progress, and mode of treatment. In periodic ophthalmia — that pest of the equine race and opprobrium of the veterinary profession — the cornea becomes suddenly opaque, the iris pale, the aqueous humour turbid, the capsule of the lens cloudy, and blindness is the result. After a time, however, the cornea clears up, and becomes as bright as ever; but the lens continues impervious to light, and vision is lost.
Ophthalmia in the dog presents us with symptoms altogether different. The conjunctiva is red; that portion of it which spreads over the sclerotica is highly injected, and the cornea is opaque. As the disease proceeds, and even at a very early period of its progress, an ulcer appears on the centre; at first superficial, but enlarging and deepening until it has penetrated the cornea, and the aqueous humour has escaped. Granulations then spring from the edges of the ulcer, rapidly enlarge, and protrude through the lids. Under proper treatment, however, or by a process of nature, these granulations cease to sprout; they begin to disappear; the ulcer diminishes; it heals; scarcely a trace of it can be seen; the cornea recovers its perfect transparency, and vision is not in the slightest degree impaired.
is a state of the orbit which requires some consideration. It is connected with the muscles employed in mastication. Generally speaking, the food of the dog requires no extraordinary degree of mastication, nor is there usually any great time employed in this operation. That muscle which is most employed in the comminution of the food, namely, the temporal muscle, has its action very much limited by the position of the bony socket of the eye; yet sufficient room is left for all the force that can be required. In some dogs, either for purposes of offence or defence, or the more effectual grasping of the prey, a sudden violent exertion of muscular power, and a consequent contraction of the temporal muscle, are requisite, but for which the imperfect socket of the orbit does not seem to afford sufficient scope and room. There is an admirable provision for this in the removal of a certain portion of the orbital process of the frontal bone on the outer and upper part of the external ridge, and the substitution of an elastic cartilage. This cartilage momentarily yields to the swelling of the muscles; and then, by its inherent elasticity, the external ridge of the orbit resumes its pristine form. The orbit of the dog, the pig, and the cat, exhibits this singular mechanism.
The horse is, to a certain extent, also an illustration of this. He requires an extended field of vision to warn him of the approach of his enemies in his wild state, and a direction of the orbits somewhat forward to enable him to pursue with safety the headlong course to which we sometimes urge him; and for this purpose his eyes are placed more forward than those of cattle, sheep, or swine. That which Mr. Percivall states of the horse is true of our other domesticated animals:
"The eyeball is placed within the anterior or more capacious part of the orbit, nearer to the frontal than to the temporal side, with a degree of prominence peculiar to the individual, and, within certain limits, variable at his will."
In many of the carnivorous animals the orbit encroaches on the bones of the face. A singular effect is also produced on the countenance, both when the animal is growling over his prey and when he is devouring it. The temporal muscle is violently acted upon; it presses upon the cartilage that forms part of the external ridge; that again forces itself upon and protrudes the eye, and hence the peculiar ferocity of expression which is observed at that time. The victims of these carnivorous animals are also somewhat provided against danger by the acuteness of sight with which they are gifted. Adipose matter also exists in a considerable quantity in the orbit of the eye, which enables it to revolve by the slightest contraction of the muscles.
We should scarcely expect to meet with cases of fracture of the orbital arch in the dog, because, in that animal, cartilage, or a cartilago-ligamentous substance, occupies a very considerable part of that arch; but I have again and again, among the cruelties that are practised on the inferior creation, seen the cartilage partly, or even entirely, torn asunder. I have never been able satisfactorily to ascertain the existence of this during life; but I have found it on those whom I have recommended to be destroyed on account of the brutal usage which they had experienced. Blows somewhat higher, or on the thick temporal muscle of this animal, will very rarely produce a fracture.
A
cases of disease in the eye may be interesting and useful.
Case
I. — The eyes of a favourite spaniel were found inflamed and impatient of light. Nothing wrong had been perceived on the preceding day. No ulceration could be observed on the cornea, and there was but a slight mucous discharge. An infusion of digitalis, with twenty times the quantity of tepid water, was employed as a collyrium, and an aloetic ball administered. On the following day the eyes were more inflamed, The collyrium and the aloes were employed as before, and a seton inserted in the poll.
Three or four days afterwards the redness was much diminished, the discharge from the eye considerably lessened, and the dog was sent home. The seton, however, was continued, with an aloetic ball on every third or fourth day.
Two or three days after this the eyes were perfectly cured and the seton removed.
Case
II. — The eye is much inflamed and the brow considerably protruded.
This was supposed to be caused by a bite. I vainly endeavoured to bring the lid over the swelling. I scarified the lid freely, and ordered the bleeding to be encouraged by the constant application of warm water, and physic-ball to be given.
On the following day the brow was found to be scarcely or at all reduced, and the eye could not be closed. I drew out the haw with a crooked needle, and cut it off closely with sharp scissors. The excised portion was as large as a small-kidney-bean. The fomentation was continued five days afterwards, and the patient then dismissed cured.
Case
III. — A pointer was brought in a sad state of mange. Redness, scurf, and eruptions were on almost every part. Apply the mange ointment and the alterative and physic balls. On the following day there was an ulcer on the centre of the cornea, with much appearance of pain and impatience of light. Apply an infusion of digitalis, with the liquor plumbi diacetatis. He was taken away on the twelfth day, the mange apparently cured, and the inflammation of the eye considerably lessened. A fortnight afterwards this also appeared to be cured.
Case
IV. — A spaniel had been bitten by a large dog. There was no wound of the lids, but the eye was protruded from the socket. I first tried whether it could be reduced by gentle pressure, but I could not accomplish it. I then introduced the blunt end of a curved needle between the eye and the lid; and thus drawing up the lid with the right hand, while I pressed gently on the eye with the left hand, I accomplished my object. I then subtracted three ounces of blood and gave a physic-ball. On the following day the eye was hot and red, with some tumefaction. The pupil was moderately contracted, but was scarcely affected by any change of light. The dog was sent home, with some extract of goulard, and a fortnight afterwards was quite well.
Case
V. — A dog received a violent blow on the right eye. Immediate blindness occurred, or the dog could apparently just discern the difference between light and darkness, but could not distinguish particular objects. The pupil was expanded and immovable. A pink-coloured hue could be perceived on looking earnestly into the eye. A seton was introduced into the poll, kept there nearly a month, and often stimulated rather sharply. General remedies of almost every kind were tried: depletion was carried to its full extent, the electric fluid was had recourse to; but at the expiration of nine weeks the case was abandoned and the dog destroyed. Permission to examine him was refused.
I have, in two or three instances, witnessed decided cases of dropsy of the eye, accumulation of fluid taking place in both the anterior and posterior chambers of the eye; there was also effusion of blood in the chambers, but in one case only was there the slightest benefit produced by the treatment adopted, and in that there was gradual absorption of the effused fluid.
About the same time there was another similar case. A pointer had suddenly considerable opacity of one eye, without any known cause: the other eye was not in the least degree affected. The dog had not been out of the garden for more than a week. The eye was ordered to be fomented with warm water.
On the following day the inflammation had increased, and the adipose matter was protruded at both the inner and outer canthus. The eye was bathed frequently with a goulard lotion. On the fourth day the eyeball was still more inflamed, and the projections at both canthi were increased. A curved needle was passed through both eyes, and there was considerable bleeding. On the following day the inflammation began to subside. At the expiration of a week scarcely any disease remained, and the eye became as transparent as ever.
A curious ease of congenital blindness was brought to my infirmary. A female pointer puppy, eight weeks old, had both her eyes of their natural size and formation, but the inner edge of the iris was strangely diseased. The pupil was curiously four-cornered, and very small. There hung out of the pupil a grayish-white fibrous matter, which appeared to be the remainder of the pupillary membrane.
Six months afterwards we examined her again, and found that the pupil was considerably enlarged, and properly shaped, and the white skin had vanished. In the back-ground of the eye there was a faint yellow-green light, and the dog not only showed sensibility to light, but some perception of external objects. At this period we lost sight of her.
A very considerable improvement has taken place with regard to the treatment of the enlarged or protruded ball of the eye. A dog may get into a skirmish, and have his eye forced from the socket. If there is little or no bleeding, the case will probably be easily and successfully treated.
The eye must, first, be thoroughly washed, and not a particle of grit must be left. A little oil, a crooked needle, and a small piece of soft rag should be procured. The blunt end of the needle should he dipped into the oil, and run round the inside of the lid, first above and then below. The operator will next — his fingers being oiled — press upon the protruded eye gently, yet somewhat firmly, changing the pressure from one part of the eye to the other, in order to force it back into the socket.
If, after a couple of minutes' trial, he does not succeed, let him again oil the eye on the inside and the out, and once more introduce the blunt end of the needle, attempting to carry it upwards under the lid with two or three fingers pressing on the eye, and the points of pressure being frequently changed. In by far the greater number of cases, the eye will be saved.
If it is impracticable to cause the eye to retract, a needle with a thread attached must be passed through it, the eye being then drawn as forward as possible and cut off close to the lids. The bleeding will soon cease and the lids perfectly close.
Ophthalmia
is a disease to which the dog is often liable. It is the result of exposure either to heat or to cold, or violent exertion; it is remedied by bleeding, purging, and the application of sedative medicine, as the acetate of lead or the tincture of opium. When the eye is considerably inflamed, in addition to the application of tepid or cold water, either the inside of the lids or the white of the eye may be lightly touched with the lancet. From exposure to cold, or accident or violence, inflammation often spreads on the eye to a considerable degree, the pupil is clouded, and small streaks of blood spread over the opaque cornea. The mode of treatment just described must be pursued.
The crystalline lens occasionally becomes opaque. There is cataract. It may be the result of external injury or of internal predisposition. Old dogs are particularly subject to cataract. That which arises from accident, or occasionally disease, may, although seldom, be reinstated, especially in the young dog, and both eyes may become sound; but, in the old, the slow-growing opacity will, almost to a certainty, terminate in cataract.
There is occasionally an enlargement of the eye, or rather an accumulation of fluid within the eye, to a very considerable extent. No external application seems to have the slightest effect in reducing the bulk of the eye. If it is punctured, much inflammation ensues, and the eye gradually wastes away.
In
amaurosis
, the eye is beautifully clear, and, for a little while, this clearness imposes upon the casual observer; but there is a peculiar pellucid appearance about the eye — a preternatural and unchanging brightness. In the horse, the sight occasionally returns, but I have never seen this in the dog.
The occasional glittering of the eyes of the dog has been often observed. The cat, the wolf, some carnivora, and also sheep, cows, and horses, occasionally exhibit the same glittering. Pallas imagined that the light of these animals emanated from the nervous membrane of the eye, and considered it to be an electrical phenomenon. It is found, however, in every animal that possesses a
tapetum lucidum
. The shining, however, never takes place in complete darkness. It is neither produced voluntarily, nor in consequence of any moral emotion, but solely from the reflection that falls on the eye.
The eye and its diseases being so concisely treated by Mr. Youatt, we are emboldened to add a more full and particular treatise on this interesting subject, couched in language the most simple, and we trust sufficiently plain to be understood by the most unscientific patron of the canine race.
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