“This case is interesting, since a single dose of antivenomous serum (20 grammes), injected two hours and a half after the accident, sufficed to cure a young man bitten by a Trigonocephalus measuring 1 metre 20 cm. in length.”

M.—Crotalus horridus.

XXXVIII.—Case recorded by Dr. P. Renaux, of Piriapolis, Uruguay (La Tribuna popular, Piriapolis, December 14, 1898).

Silverita, aged 20, bitten in the ankle by a Crotalus, on December 7, 1898. Symptoms of serious intoxication. Treated with a dose of antivenomous serum, injected half in the right flank, half in the left. Recovery.

II.—A Few Notes and Observations Relating to Domestic Animals Bitten by Poisonous Snakes and Treated with Serum.

A.—Naja haje.

XXXIX.—Case reported by Dr. Maclaud, of Konakry, French Guinea.

“A hound belonging to the Governor of Konakry was bitten in the ear by a black Naja. A similar accident happened last year, and the animal died on the fifth day. In the present case, serious phenomena had already manifested themselves: depression, convulsions, and great swelling of the entire head and anterior portion of the trunk. A dose of 10 c.c. was injected at three different points: in the flank, neck, and cellular tissue of the injured ear. Improvement was almost immediate. On the following day the animal recovered its appetite, and two days later was completely cured.”

XL.—Case reported by Dr. Marotte, of Konakry.

“At 10 a.m. on November 1, 1898, a large dog (a German brach), weighing 33 kilogrammes, was running about in some tall grass. It returned to its master, looking unhappy, with its eyelids swollen. Thinking that his dog had been bitten by a Naja, a snake which swarms round Konakry, he took it to the hospital. The animal was unable to cover the distance, which was only 300 metres; it was dragged along, but collapsed, and had to be carried. Its head was swollen, it panted, and its breathing was rapid and irregular; there was profuse salivation. On the inner face of the right ear the marks of the two fangs of the reptile were distinctly visible. A hypodermic injection of 10 c.c. of antivenomous serum was immediately given in the right flank: this was at 10.10 a.m. At 11 o’clock the symptoms appeared to become less acute; the animal was easier, and its breathing became less rapid and more regular. At 1 o’clock the animal succeeded in getting on to its feet; the œdema had somewhat diminished, and it was able to half open its eyes. At 6 o’clock the dog was taken back to its master’s house; it seemed just as lively as though nothing had happened.