We next come to its effects as an emetic. "As such," says Professor Chapman, "tobacco claims our attention. Cullen and many others opposed its use, on account of the harshness of its operation. Certainly it exceeds all others in the promptness, violence, and permanence of its impressions. But these very qualities, unpleasant as they are, enhance its value in many cases."

"Tobacco seems especially to be adapted to the evacuation of some poisons; and it has this advantage, that it acts with equal certainty and expedition, when applied to the region of the stomach in the form of a poultice, as when internally administered." Professor Barton says, he had recourse to an application of the moistened leaves of this plant to the region of the stomach, with complete success, to expel an inordinate quantity of laudanum, in a case where the most active emetics, in the largest doses, were resorted to in vain. But most poisons, particularly the corrosive, are attended with so much exhaustion, that it would seem perilous to administer tobacco, lest by its own depressing effects, the powers of vitality might be irrecoverably extinguished. In many instances, however, it appears that it may be administered in small doses with safety and advantage.

We are informed by a respectable writer, that while at the Cape of Good Hope, he had a number of Hottentots, with intermittent fever, under his care. Having few medicines, he resorted to tobacco, and found six grains of snuff as effectual in exciting vomiting, as two of Tartar emetic.

By many it is preferred in minute doses, as a nauseating medicine. Thus administered, it has succeeded in subduing some of the most violent symptoms of the most furious cases of mania; and where it cannot be given by the mouth, from the obstinacy of the patient, it may with equal benefit be applied in the form of a poultice.

As a cathartic, tobacco is entitled to notice. "Some physicians have been in the habit of prescribing this powerful substance not only for the more dangerous cases of incarcerated hernia, but in all cases of obstinate constipation, from whatever cause produced. To relieve these painful diseases, it has been usually given in the form of a clyster, regulating the dose to the age, circumstances, and strength of the patient; and it is affirmed to have proved, in many instances, very effectual, and to possess the confidence of practitioners."

I was informed by a learned and ingenious friend, that, having an obstinate case of ascaris lumbricoides in his own family, after repeated unsuccessful efforts to dislodge the worms, he at last had recourse to this potent remedy, a poultice of which he applied to the region of the stomach. The worms were almost instantaneously expelled, but with very alarming symptoms, and a complete prostration of the patient. From these circumstances, we should be led to conclude, that its efficacy as a vermifuge defends either upon its narcotic properties, or upon its sudden and powerful effect as a cathartic.

Its effects as a sternutatory, i. e. as exciting to sneeze, are known to all. If applied to the nostrils, in the form of a powder or snuff, it produces violent and repeated sneezing, with a slight degree of vertigo. The violent agitation produced in this way, together with a copious discharge from the nostrils, often relieves catarrh, headache, and incipient opthalmia or inflammation of the eyes. But habit soon blunts the sensibility of the organs, and much positive injury follows the habitual use of snuff. It has been a popular remedy in many places for the cure of scald-head, psora, and most other cutaneous eruptions. It has also been applied for cleansing ulcers, and for the removal of indolent tumors. But the dreadful effects produced by it when absorbed into the system, have induced most medical men to abandon it altogether, and prescribe a more safe application.

Though it is said, by Dr. Brailsford, to be a sudorific of considerable efficacy, I am in possession of no facts which go to support such a conclusion, unless indeed it be the fact, that it in an eminent degree brings on that cold perspiration of which we have spoken, and which is, in many instances, the immediate precursor of death.

But of all others, its diuretic properties have been the most lauded. Dr. Fowler was the first to bring them extensively into notice. In dropsy, dysury, gravel, and nephritis calculosa or inflammation of the kidneys, the infusion and tincture were given by him with astonishing success. In spasmodic asthma, the same distinguished physician found it to afford relief.

Mr. Earle, a surgeon of some eminence, has more recently treated several inveterate cases of retention of urine on the same plan and with similar effects, and adds his testimony to its efficacy in tetanus, trismus, and other spasmodic affections. Of its power to relieve spasm there can be no doubt. What has been related of its sedative qualities, is abundantly sufficient to establish that fact. Cramps, convulsions, and even the vital principle itself, give way before the exhibition of this deadly narcotic. Hence, to its power of prostrating the muscular energy, it owes its efficacy in preventing retention of urine.