The Queen of the West went down the Mississippi, destroying skiffs and flatboats whenever found, as far as the Red River, which was reached on the morning of the 12th. Going up the Red River to the point where the Atchafalaya Bayou branches off on its way to the Gulf, the De Soto and barge were secured there, while the Queen went down the bayou destroying Confederate Government property. In performing this service one of her officers was wounded by a party of guerillas. Returning to the De Soto, the two started up Red River. On the morning of the 14th a transport, called the Era No. 5, was captured with two Confederate officers. Hearing that there were three large boats lying, with steam down, at Gordon's Landing, thirty miles higher up (about seventy-five miles from the mouth of the river), Colonel Ellet decided to attempt their capture. On rounding the bluff above which they were lying, the Queen was fired upon by a battery of four 32-pounders. Orders were immediately given to back down behind the bluff, but by some mishap she ran aground on the right side, in plain view of the battery, within easy range and powerless for offence. Here she received several shots, one of which, cutting the steam-pipe, stopped the engines, that had been backing vigorously. Nothing further in the way of escape was tried, and the commanding officer was deterred from setting fire to the ship by the impossibility of removing the wounded officer.

The Queen and the De Soto each had but one boat, and in the panic that followed the explosion a party took possession of the Queen's and made off with it to the De Soto, under the pretext of hurrying that vessel up to the assistance of her consort; so the remainder of the ship's company, including her commander, made their escape to the other steamer on cotton bales. The De Soto sent up her yawl, which took off one load, getting away just before the Confederates boarded their prize.

The De Soto now started on a hurried retreat down the river, but running into the bank she lost her rudder. Deprived of the power of directing her motions, she was allowed to drift with the stream, picking up, from time to time, a fugitive on a bale, and was rejoined by her yawl about ten miles lower down. Shortly after this the parties fell in with the prize of the morning, when the De Soto was burned and the hasty flight continued in the Era. The following morning the Mississippi was reached, and the day after, the 16th, they met the Indianola eight miles below Natchez.

The Queen of the West had thus passed practically unhurt into Confederate hands, the manner of her loss giving another instance of how lack of heed in going into action is apt to be followed by a precipitate withdrawal from it and unnecessary disaster. Colonel Ellet's only reason for not burning the Queen was that he could not remove one of her officers, who had been wounded the day before. If he had transferred him to the De Soto before going under the battery with the Queen, the fighting ship, this difficulty would not have existed. No one seems to have been hurt, by the Union and Confederate reports, and it is hard to avoid the conclusion that Ellet's rashness in exposing his vessel, though he knew the Indianola was to be sent down, was not atoned for by sticking to her until he had destroyed her. The accidents were of a kind most likely to happen, and very simple appliances that might have been all ready would have ensured her burning. It is to be remembered, however, that Colonel Ellet was at this time not twenty years old.

On receiving the news of the disaster, Lieutenant-Commander Brown decided to go down as far as the mouth of the Red River. The same day was met off Ellis's Cliff the Confederate gunboat Webb, which had been lying at Alexandria and had started in hot pursuit of the fugitives from the Queen of the West. Upon making out the Indianola, which she had not expected, the Webb at once turned, and having greater speed easily escaped; the Indianola following down to the mouth of the Red River. Here she anchored and remained three days, while the Era, on the 18th, returned to the neck below Vicksburg.

Brown now learned that the Queen of the West had not been so much injured as her late commander had thought, and that a combined attack would probably be made by her and the Webb upon the Indianola. Two cottonclad boats were also in preparation by the Confederates for the same purpose. In view of these facts he determined to go up the Mississippi and get cotton, with which better to protect the Indianola against boarders by filling up the gangways between the casemates and the wheels. By the time this was done, having as yet met no other vessel of the squadron, though he had hoped for reinforcements when the loss of the Queen became known, he had reached the decision to return and communicate with the admiral.

With two barges alongside, the progress of the Indianola against the current was slow—too slow, for the swift rams of the enemy were already on her track; but although Brown had kept the bunkers of the Indianola full, he confidently expected to meet another boat which would need the coal, and was unwilling to sink it. The smoke of the pursuers had been seen throughout the day, and at 9.30 P.M. of the 24th four steamers were made out. These were the rams Queen and Webb, the former in charge of Captain McCloskey, the latter of Captain Pierce; Major J.L. Brent, of General Taylor's staff, having command of this part of the expedition, which was fitted out in Alexandria and accompanied by a tender called the Grand Era. These had been joined before leaving the Red River by the cottonclad steamer Batey from Port Hudson, carrying 250 riflemen under Lieutenant-Colonel Brand, whose rank entitled him to command the whole.

The enemy used the advantage of their greatly superior speed to choose the night for attacking, that the Indianola might not fire with the certainty of clear sight. They first saw her near Palmyra Island, a little above New Carthage, and were themselves made out at the same instant. The Indianola at once went to quarters and cleared for action, continuing up stream till her preparations were made; then she turned and stood down. The channel above Palmyra Island at that time hugged the eastern shore, crossing to the western just above the island, and the Indianola seems to have been in this place when the enemy coming up describes her as "with her head quartering across and down river," presenting the port bow to their approach. The order of advance was with the Queen leading, the Webb five hundred yards astern, and the two other boats lashed together some distance in the rear. The Queen dashed up, firing her light pieces to no purpose when one hundred and fifty yards off, and endeavored to ram the Indianola abaft the port wheel; but the latter, backing, received the blow on the barge, through which the enemy's sharp bow passed but without injuring her opponent. The barge went adrift and sunk. The Webb followed, and, the Indianola standing for her at full speed, the two came together bows on with a crash that knocked down most of their crews. The Webb's bow was cut in for a distance of eight feet, extending from two feet above the water-line to the keelson, but as she was filled in solid for more than eight feet she did not sink. The Indianola received no damage.

A third blow was delivered on the starboard side by the Webb, in what manner does not appear precisely, with the effect of crushing the other barge, leaving it hanging by the lashings, which were then cut adrift. The Webb passed up following the Queen. The latter, having gained sufficient distance, turned and charged down, but as the Indianola was turning up at the same moment the blow on the starboard bow glanced, the vessels rasping by each other; and as the Queen cleared the stern of her enemy, the latter planted two IX-inch shot successfully, killing 2 and wounding 4 of her crew and disabling two guns. During all this time the Indianola kept firing her guns whenever they could be made to bear, but, as the enemy had calculated, the darkness of the night prevented them from doing as much execution as they otherwise would. The rams also kept up a constant firing with their musketry and light guns. In the uncertain light it was very difficult to watch the two assailants through the peep-holes in the pilot-house of the gunboat, but yet a fifth blow was received forward of the wheels without injury. At last, however, the Queen was able to strike just abaft the starboard wheel-house, crushing the wheel, disabling the starboard rudder, and starting a number of leaks abaft the shaft. The starboard engine was thus useless and the Indianola helpless to avoid the onset of the Webb, which struck her fair in the stern, starting the timbers and starboard rudder-box so that the water poured in in large volumes. This settled the fight, and Brent reported to Colonel Brand that the enemy was disabled. The Batey then dashed up to board, but the Indianola, after delaying a few moments in mid river, till the water had risen nearly to the grate-bars, to assure her sinking, had run her bows into the west bank, and surrendered as soon as the cottonclads came alongside. The enemy, finding that she must sink and not willing that this should happen on the side where the Union army was, made fast at once two steamers and towed her down and over to the east bank, where she sank in ten feet of water near the plantation of the President of the Confederacy. The loss of the Indianola was 1 killed, 1 wounded, and 7 missing. The latter probably got ashore on the west bank, for 3 were captured there the following day and more than one got through to Porter's squadron. The loss of the enemy was officially stated at 3 killed and 5 wounded, but a Confederate officer admitted to the commander of the Indianola that it was much greater.

This ended Porter's sanguine hopes of blockading the river by detached vessels while he kept the body of the fleet above. After being harassed and stirred up during three weeks, the Confederates again found themselves masters of the line from Vicksburg to Port Hudson for a few days longer, and with two Union vessels in their hands, one of which was serviceable, while the other, badly damaged and partly sunk, it is true, had still her armament intact and was possibly not beyond repair. Their possession of the Indianola, however, was of short duration. The second day after the capture, a detail of 100 men with a lieutenant was sent to try and save her, by the army officer commanding near by, while the Queen of the West went up to Warrenton, to act as picket for the fleet, and with despatches to General Stevenson, commanding at Vicksburg, asking for pumps and other help. In a short time, the Queen returned in great haste and reported a gunboat approaching. All the vessels that had behaved so gallantly two nights before got under way in a panic and went hurriedly down, leaving the working party and the lieutenant. The gunboat did not come nearer than two miles and a half, and seemed very apprehensive of an attack herself, sticking close to the bank. The lieutenant stood his ground for one day; but then finding himself deserted by his own fleet, which by this time was up Red River, and the gunboat still lying, terrible though inert, just above him, he, the next evening, laid the two XI-inch guns muzzle to muzzle, and so fired them. One was burst, the other apparently only kicked over. He next threw overboard two field pieces he had with him, made an attempt to blow up the vessel, which resulted in destroying the forward casemate and burning most of the wreck above water, and then fled with his command.