The inflammatory fever called tabardillo is common in the hot as well as cold climates. The curative method adopted by the indians may, in its prognostic, be considered an improvement on the cold affusion. Some clay is procured, and mixed with water until it acquire the consistency of batter, the patient is smeared all over his body with it; after an hour or two an examination takes place, and if the clay has become parched, and is peeled off, death is considered to be the inevitable result; but if it be cracked, and the pieces adhere to the body, a favourable result is expected. This is most probably the fruit of observation, as I believe the science of medicine among such people generally is; but the effect of the application in the latter case is a copious perspiration, which is absorbed by the clay, by which an adhesion to the cutis takes place, and prevents it from falling off; thus the experiment, if not at first founded on scientific principles, has been undoubtedly supported by practical facts.

The bicho is an endemical disease, known only in the hot valleys; it is an ulcer of a gangrenous tendency in the colon, and if not attended to in time is generally mortal. The indians use very stiptic injections, and believe the origin to be caused by a grub, bicho. Those who reside in cold climates, and when in the valleys eat abundance of fruit, are most subject to this disease.

The pasmo is generally brought on by wetting a wound, or ulcer, with cold water; it is particularly prevalent in the hot climates of the valleys; it is a general nervous convulsion; the first effects are a tetanus, after which the most excruciating pains afflict the patient, until relieved by death, for no remedy has as yet been found effectual.

The bronchocele, or goitres, is common in some parts of these provinces, particularly in the neighbourhood of Huacaibamba; it is a disagreeable affliction without any known antidote.

The syphilis, as I have before observed, is extremely virulent in the cold climates of the interior; the usual remedies applied are sarsaparilla, guaiacum, and sassafras, but very seldom mercury, owing to the dread that the natives have of its administration.

Madness in dogs was unknown in America until the year 1803, when it made its appearance along the coast between Paita and Lima; in 1807 many were affected with it in Lima, to the southward as far as Arica, and Arequipa, and to the northward of Lima in the valleys of the interior. Dr. Unanue says, "after having collected all the data, and having consulted those of the faculty, and other intelligent persons who had witnessed the effects, I have deduced,

"Firstly—That this spontaneous madness originated in the excessive increase of heat in 1803 and 1804, which caused almost all kinds of animals to throw themselves into the pits and lakes to refresh themselves.

"Secondly—That this disease attacked indiscriminately all kinds of quadrupeds, some of which, in the most furious manner, tore the flesh from their bones with their teeth: several men were also affected with symptoms of hydrophobia without having been bitten by any animal.

"Thirdly—It was most common among dogs; but some, although apparently affected, caused no symptoms in their bite except the ordinary ones; but from the bite of others on their own species, other quadrupeds, and men, the most dreadful symptoms of hydrophobia were propagated. On one of the plantations an overseer distributed among the slaves the meat of several animals which had died mad, believing that the meat was not contagious; but several of the negroes who ate of it died in a state of madness.