The following is a very simple receipt for the preparation of the mel helleboratum or honey of hellebore: “Take of the roots of white hellebore, dried and sliced, one pound; of clarified honey, three pounds; of water four pints. After steeping the roots three days in the water, boil them a little while, then boil the liquor, well pressed out and strained, with the honey to a due consistence.” Dr. Pemberton (London Dispensatory, A. D. 1746.) By due consistence is meant the consistence of honey.
SECT. XI.—ON THE DIFFERENT KINDS OF ANTIDOTES.
The Preface of Galen’s work on Antidotes. Those compositions which cure affections not when they are applied externally, but when taken internally, are named antidotes by the ancients. There are three different kinds of them. The first are those which are administered for deleterious substances; the second, for those animals called venomous; and the third are the remedies for affections occasioned by bad articles of food. Some antidotes profess to fulfil all these three purposes, such as the one called theriac.
The preparation of the hedychroum, which forms an ingredient of the theriac. Of the bark of the root of aspalathus, of calamus aromaticus, of costus, of asarabacca, of xylobalsam, of valerian, of amaracus, of mastich, of each, dr. vj; of carpobalsam, dr. ij; of marum, dr. xvj; of the flower of the rush, dr. ij; of cinnamon, dr. xxiv; of amomum, of cassia, of rheum, of each, dr. viij; of Indian nard, of the cassia leaf (malabathrum), dr. xij; of myrrh, dr. xxiv; of saffron, dr. xij; mix with fine wine, and form into trochisks, having smeared the finger with opobalsam.
The preparation of trochisks of squills. Having covered over the squills with clay or dough, roast it moderately, and taking of the inner parts of it, p. ij; and of the flour of tares, p. j; and having triturated in like manner, form trochisks.
The preparation of the theriac trochisks. Having chosen four or five vipers of a tawny colour, and recently taken, cut off their heads, and four fingers’ breadth of the part next the tail, and having removed the skins and entrails, boil the rest in a new pot, with dill and a moderate quantity of salts, until the spines be separated from the flesh. Then removing and cleaning away properly the flesh from the spines, and having mixed with them an equal quantity of clean bread, and triturated them in like manner, form into small balls, having your fingers smeared with opobalsam, and cool in the shade.
The preparation of the theriac antidote. Of the trochisks of squills, dr. lxviij; of the theriac trochisks, dr. xxiv; of hedychroum, dr. xxiv; of cinnamon, dr. xxiv; of common pepper, dr. xxiv; of the juice of poppies, dr. xxiv; of dried roses, dr. xv; of water-germander, of rape-seed, of Illyrian iris, of agaric, of liquorice, of opobalsam, of each, dr. xij; of myrrh, of saffron, of ginger, of rhaponticum, of the root of cinquefoil, of calamint, of horehound, of stone-parsley, of cassidony, of costus, of white and long pepper, of dittany, of the flower of sweet rush, of male frankincense, of turpentine, of mastich, of black cassia, of spikenard, of each, dr. vj; of the flower of poley, of storax, of parsley-seed, of seseli, of shepherd’s pouch, of bishop’s weed, of germander, of ground pine, of the juice of hypocistis, of Indian leaf (malabathrum), of Celtic nard, of spignel, of gentian, of anise, of fennel-seed, of Lemnian earth, of roasted chalcitis, of amomum, of sweet-flag, of balsamum, of Pontic valerian, of St. John’s wort, of acacia, of gum, of cardamom, of each, dr. iv; of carrot-seed, of galbanum, of sagapen, of bitumen, of opoponax, of castor, of centaury, of the species of birthwort called clematis, of each, dr. ij; of Attic honey, lb. x; of Falernian wine, oz. ij. Put into a mortar the opium, hypocistis, myrrh, sagapen, liquorice, storax, acacia, and opoponax, and having poured in some honey pound and dissolve: then pouring in wine so as to cover them, macerate for three days; then having pounded the others, unite them, and scum the honey. It is to be laid up in vessels of silver or glass, not quite full, and the covers taken off every day. In case of need it may be used for persons bitten by venomous animals, and those who have taken anything poisonous, after seven years, a quantity of it, to the size of a filbert, being drunk twice a day, in three cyathi of wine. In like manner, to those who are in a dangerous state from some obscure cause, when the disorder in the body imitates the quality of a mortal poison, as is the case particularly in pestilential diseases, it is to be given once a day. But in all other affections, it is to be used from the tenth to the twentieth year. For coughs, pains of the chest or side, it is to be given at night, if free from fever, with wine and honey; but if feverish, with hydromel, to the extent of an Egyptian bean. In all cases of hæmoptysis, it is to be given morning and evening, to the size of an Egyptian bean; if recent, in oxycrate; or, if chronic, in the decoction of comfrey. In cases of flatulence, tormina, or cæliac affections, it is to be taken in the morning, to the size of an Egyptian bean, in hot water. It excites an intense appetite, and removes rigors, coldness, and vomiting of bile when drunk before the attack. It promotes menstruation, and expels the fœtus when dead, if drunk to the size of an Egyptian nut with honeyed water, or sweet wine, in which rue or dittany has been boiled. In the case of loss of voice, it is drunk alone, and with double the quantity of tragacanth in wine and honey, or sweet wine, being retained under the tongue and allowed to melt. For diseases of the spleen or liver, it is given with oxycrate; but if they are in a scirrhous state, with a cyathus and a half of oxymel, or vinegar of squills. For nephritic complaints, it is given with oxymel to the size of an Egyptian bean. In dysenteric cases it is given to the same amount, with the decoction of sumach, morning and evening. For dimness of vision it answers excellently thus: Mix oz. ij of the antidote, and of opobalsam, with one cyathus of honey, and after a little anoint with it. It is also used as a dentifrice. Many, for the sake of prophylaxis, take it at new moon to the size of a Grecian bean, after digestion, with a cochleare of honey and two cyathi of water. In like manner they use it when upon a journey they suspect that the air or water is bad.
Theriac salts. Take four female vipers recently caught; and then putting into a mortar one Italian modius of ammoniac or common salt, pound into thick pieces, along with it, of gentian, lb. iss; of round birthwort, lb. iss; of the hair of the small centaury, lb. ij; of cardamom, of horehound, of each, oz. vj; of water germander, of parsley, of Cretan germander, of each, lb. j; of the seed of garden rue, sext. ij: unite these with a sufficient quantity of Attic honey, and throwing the half of them into a new pot, and then the four vipers alive, add to them fresh tender squills, cut into small pieces, and then join to them the remaining half of the mixture formerly mentioned. Then having covered up the pot carefully, make three or four perforations in its lid to allow the vapour to escape, that it may indicate to you the progress of the operation of roasting. At first much smoke will be seen issuing, fuliginous and very turbid, indicating that the fire is acting upon the animals. You must then take care lest you inhale any of this smoke, which is infected with the exhalation from the vipers. When this vapour has ceased, you may see a fine flame issuing through the holes, by which you may know that they are properly roasted. Then having removed the pot from the fire, and allowed it to cool for a whole day and night, take out the ashes, pound them carefully, and sift them along with these mixtures: of the seed of wild rue, of Cretan hyssop, of each, oz. ix; of the seed of fennel, of Celtic nard, of Scythian base horehound, of each, oz. vj; of Macedonian stone-parsley, of Indian leaf, of each, oz. iv; of amomum, of grapes, of the seed of horminum toasted, of each, oz. iij; of the shoots of marjoram, of the shoots of thyme, of each, oz. ij; of juniper berries, of white and of long pepper, of each, lb. j; of the root of laserwort, oz. x; of coriander seed, of ginger not perforated, of the seed or root of satyrium, of pennyroyal, of the seseli of Marseilles, of mint, of each, oz. vj; of cassia fistula, oz. ij; of cinnamon, oz. j. I, however, have made the preparation, so that I did not burn the animals, but mixed the trochisks from them, as related under the theriac, with those things which are burnt along with the vipers, that the bitterness which they have in them may be laid aside during the burning. I added just such a proportion of the trochisks as I conjectured to agree with the contents of the four vipers. And truly in this way they turned out excellent.
The Mithridatic antidote from scinks. Of troglodytic myrrh, of ginger, of cinnamon, of each, dr. x; of spikenard, of frankincense, of shepherd’s pouch, of opobalsam, of schœnanth, of costus, of cassidony, of seseli, of galbanum, of turpentine, of long pepper, of castor, of hypocistis juice, of storax, of the leaves of malabathrum, of each, dr. iv; of black cassia, of poley, of white pepper, of water germander, of carrot-seed, of carpobalsam, of cyphi, of bdellium, of Celtic nard, of gum, of stone-parsley, of opium, of cardamom, of the seeds of fennel, of gentian, of rose-leaves, of each, dr. viij; of dittany, of anise, of sweet flag, of valerian, of each, dr. iij; of Athamantic spignel, of acacia, of the belly of a scink, of the seed of St. John’s wort, of each, dr. iss; of wine and honey, q. s. Prepare it in like manner as the theriac. Galen says, that it applies to the same cases as the theriac, with the exception of those who have been bitten by the viper, for there the theriac is more efficacious.
The antidote from different kinds of blood being a remedy against all venomous animals and deadly poisons. Of white and long pepper, of costus, of sweet flag, of valerian, of anise, of Cretan dittany, of each, dr. ij; of amomum, of opobalsam, of the seed of wild rue, of the seed of fennel, of Ethiopian cumin, of dill, of the dried blood of a male duck, of the blood of a kid, of the blood of a goose, of the blood of a female duck, of the seed of the wild rape, of each, dr. iij; of gentian root, of trefoil, of the schœnanth, of frankincense, of dried roses, of each, dr. iv; of cinnamon, dr. ij; of water germander, dr. viij; of stone-parsley, of poley, of myrrh, of nard, of each, dr. vj; of cassia, dr. iij; of Cyrenaic juice, dr. iij; of cassidony, dr. v; of asarabacca, dr. ij; of ammoniac perfume, dr. iij; of Athamantic spignel, dr. ij; of agaric, dr. ij; of carpobalsam, gr. xx; of boiled honey, q. s.