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Cardinal Wolsey occupied a prominent position in England at this time, and he was a very good friend to Katharine until she felt compelled to express her opinion of a certain bad action of his, which was brought about in this way: One day the Duke of Buckingham was holding the basin for the king to wash his hands when the cardinal poked his in also. The duke became very indignant at such presumption, for he considered it beneath his dignity to perform such an office for anybody but his sovereign; he therefore flung the water all over the cardinal's feet, whereupon that worthy prelate scowled revengefully, and angrily a horse and hunt as Englishwomen did. For his sake she pretended to like games, though she really had little taste in that direction. Even after her misfortunes began, the great Erasmus said to Henry: "Your noble wife spends the time reading the sacred volume which other princesses occupy with cards and dice." That renowned scholar always held her up as an example to her sex, and dedicated a very important work to her, called "Christian Matrimony." threatened punishment. He carried it into effect, and succeeded in causing the execution of the duke on a charge of treasonable sorcery.

Buckingham had been one of Katharine's earliest friends in England, and she could not help remonstrating against the injustice of his sentence. She even pleaded for him with the king, but failed. Wolsey's opposition was too strong, so Katharine revenged herself by openly censuring his cruel conduct, for which he never forgave her.

The next year Charles V. visited his aunt again at Greenwich Palace. He came really for the purpose of urging the king to make war against France, though he pretended that it was to engage himself to his little cousin, Princess Mary, then only six years old.

Queen Katharine met him at the hall-door, with her daughter by her side, and blessed him as he kneeled down before her. He stayed in England six weeks, and the result of his visit was more fighting in France.

Then Anne Boleyn returned home, and was appointed maid of honor to Queen Katharine. She was a great beauty, and such a belle at court that unhappily Henry fell in love with her. But he did not make his feelings known just then because the queen's health was very bad, and no doubt he flattered himself that she might accommodate him by dying, and thus spare him the trouble of a divorce. However she grew better, and then, with Wolsey's assistance, Henry began to make plans for ridding himself of her. His first step was to complain to his confessor that his conscience troubled him for having married his brother's widow, but it seems strange that that inward monitor had been silent for so many years. He set spies to watch Katharine's actions, hoping, no doubt, that something might be discovered to help his cause; but he was disappointed, and the queen was secretly informed of his intentions. Naturally she was very indignant, and wanted to consult her nephew, Charles V., as to what she ought to do. For that purpose she sent a faithful servant, but he was stopped on the way by one of Wolsey's agents.

She then expressed her intention of going to law about the matter, and consulted her confessor, hoping that it would be laid before the church. The poor, friendless woman might have known that she could scarcely look for justice in a land not her own against a popular sovereign and his all-powerful adviser. She had an interview with her husband, but he put her off with deceitful excuses and fair promises, and she was forced to await patiently whatever his pleasure might prompt.

In the meantime a pestilence broke out in London, and several of the royal household died of it. This so alarmed Henry that he made thirty-nine wills, confessed his sins every day, and passed most of his time in penitence and prayer, his only recreation being the mixing of medicines and the compounding of plasters and ointments. He even sent Anne Boleyn home to her relations. But no sooner did the pestilence disappear than his jovial spirits returned, and he began to write daily love-letters to his favorite. Wolsey, to aid the king's divorce, had made the pope believe that Katharine wished to retire from the world and lead a religious life, and it is possible that he thought she might be persuaded to do so.