Epitome of the Pharmacopeia of the United States and the National Formulary / With Comments

by Albion Walter Hewlett; William August Puckner; Torald Hermann Sollmann; Martin I. Wilbert

Action and Uses: Identical with those of cinchona. Used as ingredient of the compound tincture of cinchona.

*Tinctura Cinchonae Composita (Tr. Cinch. Co.), Compound Tincture of Cinchona, U.S.P.—Red cinchona (10%), yielding about 0.45 per cent. of cinchona alkaloids, serpentaria (2%) and bitter orange peel, in glycerin, alcohol and water. Absolute alcohol content about 64 per cent.

Uses: Aromatic astringent bitter, of high alcoholic content; superfluous.

Dosage: 4 Cc. or 1 fluidrachm (U.S.P.).

Cinchonidinae Sulphas (Cinchonid. Sulph.), Cinchonidine Sulphate, U.S.P.—The sulphate of the alkaloid cinchonidine, obtained from cinchona bark.

White, glistening, odorless needles with a very bitter taste. Soluble in water (1:65) and in alcohol (1:90).

Action and Uses: Formerly used as a cheap substitute for quinine sulphate, over which it possesses no advantage, being less efficient and more convulsant.

Dosage: 0.15 Gm. or 2-1/2 grains (U.S.P.).

Cinchoninae Sulphas (Cinchonin. Sulph.), Cinchonine Sulphate, U.S.P.—The sulphate of the alkaloid cinchonine, obtained from cinchona bark.

White, lustrous, odorless crystals with a very bitter taste. Soluble in water (1:60) and in alcohol (1:12.5).