Epitome of the Pharmacopeia of the United States and the National Formulary / With Comments

by Albion Walter Hewlett; William August Puckner; Torald Hermann Sollmann; Martin I. Wilbert

Dosage: 2 Cc. or 30 minims (U.S.P.).

Guaiaci Lignum (Guaiac. Lig.), Guaiac Wood, N.F. (Lignum Vitae).

Action and Uses: Reputed “alterative,” but without established value. No advantage over guaiac resin.

Dosage: 4 Gm. or 1 drachm (N.F.).

*Guaiacol (Guaiacol), Guaiacol, U.S.P.—Obtained from wood-tar creosote or prepared synthetically.

Colorless or yellowish solid or liquid, with an aromatic odor and a strong phenolic taste. Soluble in water (1:53), freely soluble in glycerin (1:0.8) and miscible with alcohol, chloroform or ether.

Action and Uses: Used as intestinal antiseptic and bronchial stimulant, similar to creosote; less irritant but also less active. Inunction with 50 per cent. solution in oil is antipyretic but it is less powerful and more uncertain than acetphenetidin, etc. Action is difficult to control and collapse may occur.

Dosage: 0.5 Cc. or 8 minims (U.S.P.).

*Guaiacolis Carbonas (Guaiacol. Carb.), Guaiacol Carbonate, U.S.P.

White, nearly odorless and nearly tasteless powder. Soluble in alcohol (1:60) and in ether (1:18); insoluble in water.