Dosage: 4 Cc. or 1 fluidrachm (N.F.).
Hydrastininae Hydrochloridum (Hydrastinin. Hydrochl.), Hydrastinine Hydrochloride, U.S.P. (Hydrastinine Chloride).—The hydrochloride of hydrastinine, an alkaloid obtained synthetically from hydrastine.
Yellowish, odorless crystals or powder. Soluble in chloroform (1:195); very soluble in water and alcohol.
Action and Uses: Hydrastinine resembles hydrastine in its action but is said to be less depressing. Hydrastinine has a pronounced pressor effect on peripheral vessels, causing a rise of blood pressure.
Dosage: 0.03 Gm. or 1/2 grain (U.S.P.).
*Hydrastis (Hydrastis), Hydrastis, U.S.P. (Golden Seal).—Rhizome and roots, yielding not less than 2.5 per cent. of ether-soluble alkaloids, chiefly hydrastin.
Action and Uses: Hydrastis is an unpleasant bitter; it possesses no advantages over other simple bitters (gentian). It has been asserted to have a special influence on mucous membranes favoring their nutrition and return to a normal condition. There is little or no experimental evidence to bear out the claim for any special action.
Dosage: 2 Gm. or 30 grains (U.S.P.).
Extractum Hydrastis (Ext. Hydrast.), Extract of Hydrastis, U.S.P. (Extract of Golden Seal, Powdered Extract of Hydrastis).—One Gm. extract represents about 4 Gm. hydrastis. Yields about 10 per cent. of alkaloids.
Dosage: 0.5 Gm. or 8 grains (U.S.P.).