Epitome of the Pharmacopeia of the United States and the National Formulary / With Comments

by Albion Walter Hewlett; William August Puckner; Torald Hermann Sollmann; Martin I. Wilbert

Hyoscyaminae Hydrobromidum (Hyoscyamin. Hydrobr.), Hyoscyamine Hydrobromide, U.S.P. (Hyoscyamine Bromide).—Obtained from hyoscyamus and other plants of the nightshade family.

White, odorless crystals. Freely soluble in alcohol (1:2.5) and in chloroform (1:1.7); very soluble in water.

Action and Uses: Similar to those of atropine; is usually more sedative to the brain, but at times produces acute delirium. The drug is very uncertain.

Dosage: 0.3 mg. or 1/200 grain (U.S.P.).

*Hyoscyamus (Hyosc.), Hyoscyamus, U.S.P. (Henbane, Hyoscyami Folium, P.I.).—Leaves and tops, yielding not less than 0.065 per cent. of alkaloids.

Action and Uses: Similar to those of belladonna.

Dosage: 0.25 Gm. or 4 grains (U.S.P.).

Extractum Hyoscyami (Ext. Hyosc.), Extract of Hyoscyamus, U.S.P.—One Gm. extract represents about 4 Gm. hyoscyamus. Yields about 0.25 per cent. of alkaloids.

Dosage: 0.06 Gm. or 1 grain (U.S.P.).

Fluidextractum Hyoscyami (Fldext. Hyosc.), Fluidextract of Hyoscyamus, U.S.P. (Fluidextract of Henbane).—Hyoscyamus (100%) yielding about 0.065 per cent. of alkaloids, chiefly hyoscyamine. Absolute alcohol content about 60 per cent.