[467] Various papers in Journ. Chem. Soc., 1892-1894.


Three of the alkaloids have been fairly well worked out; the fourth homo-napelline has not yet been satisfactorily investigated.

The three alkaloids are aconitine, aconine and benzoyl-aconine; besides which pyraconitine and pyraconine can be obtained by suitable treatment from aconitine and aconine.

The formulæ of the alkaloids and their derivatives are as follows:—

Aconitine (acetyl-benzoyl-aconine),m.p., 188·60°,C33H45NO12
Benzoyl-aconine,m.p., 268·0°,C31H43NO11
Pyraconitine (anhydro-benzoyl-aconine),m.p., 188-190°,C31H41NO10
Aconine,m.p., 132°,C24H39NO10
Pyraconine (anhydro-aconine), C24H37NO9

§ 424. Aconitine, C33H45NO12.—This base has been shown by Dunstan to be acetyl-benzoyl-aconine; one molecule of the base breaking up, on complete hydrolysis, into one molecule of aconine, one of acetic acid, and one of benzoic acid—

Acetic
Acid.
Benzoic
Acid.
Aconine.
C33H45NO12+2H2O=C2H4O2+C7H6O2+C24H39NO10.

That is to say that 100 parts of aconitine, according to theory, should yield:—