If infection of the bladder and the formation of bed-sores are prevented, the patient may live for months or even for years. At any time, however, infection of the bladder may occur and spread to the kidneys, setting up a pyelo-nephritis; or the patient may develop an ascending myelitis, and these conditions are the most common causes of death.
Lumbo-sacral Region.—All the spinal segments representing the lumbar, sacral, and coccygeal nerves lie between the level of the eleventh thoracic and first lumbar vertebræ. Injuries of the lower thoracic and upper lumbar vertebræ, therefore, may produce complete paralysis within the area of distribution of the lumbar and sacral plexuses. The anæsthesia reaches to about the level of the umbilicus. There is incontinence of urine and fæces from the first. Priapism is absent. Bed-sores and other trophic changes are common, and there is the usual risk of complications in relation to the urinary tract.
Conus Medullaris.—A lesion confined to the conus medullaris may result from a fall in the sitting position. It is attended with slight weakness of the legs, anæsthesia involving a saddle-shaped area over the buttocks and back of the thighs, the perineum, scrotum, and penis. The urethra and anal canal are insensitive, and there is paralysis of the levatores ani, the rectal and the vesical sphincters. The testes retain their sensation.
Cauda Equina.—As the cord terminates opposite the lower border of the first lumbar vertebra, injuries below this level implicate the cauda equina. The extent of the motor and sensory paralysis varies with the level of the lesion and with the particular nerves injured. Sometimes it is complete, sometimes, selective. As a rule all the muscles of the lower extremity are paralysed, except those supplied by the femoral (anterior crural), obturator, and superior gluteal nerves. The perineal and penile muscles are also implicated. There is anæsthesia of the penis, scrotum, perineum, lower half of the buttock, and the entire lower extremity, except the front and lateral aspects of the thigh, which are supplied by the lateral cutaneous nerve and the cutaneous branches of the femoral (anterior crural). There is incontinence of urine and fæces. The prognosis is more favourable than in lesions affecting the cord itself, and the only risk to life is the occurrence of infective complications.
Partial Lesions of the Cord and Nerve Roots.—Partial lesions, such as bruises, lacerations, or incomplete ruptures, are always attended with hæmorrhage into the substance of the cord, and usually result from distortions or incomplete fractures and dislocations of the spine, or from bullet wounds. They are comparatively rare.
When the nerve roots alone are injured, sensory phenomena predominate. Formication, radiating pains, and neuralgia are present in the area of distribution of the nerves implicated. There is motor paresis or paralysis, which may disappear either suddenly or gradually, or may persist and be followed by atrophy of the muscles concerned. In contrast to what is observed from pressure by tumours and inflammatory products, twitchings and cramps are rare.
In partial lesions of the cord the motor phenomena predominate. Paresis extends to the whole of the motor area below the seat of the lesion, but the weakness is more marked on one side of the body. The distal parts—feet and legs—suffer more than the proximal—arms and hands, and the extensors more than the flexors. The paresis develops slowly, varies in extent and degree, and may soon improve. Vaso-motor disturbances accompany the motor symptoms. Irritative phenomena, such as twitchings or contractures, may come on later.
The deep reflexes, particularly the knee-jerks, may be absent at first, but they soon return, and are usually exaggerated; a well-marked Babinski response may appear later. Abolition of the reflexes, therefore, does not necessarily indicate complete destruction of the cord, but their return is conclusive evidence that the lesion is a partial one. It is necessary, therefore, to defer judgment until it is determined whether the abolition of the reflexes is temporary or permanent.
Sensory disturbances may be entirely absent. When present, they are incomplete, and are chiefly irritative in character. They may not reach the same level as the motor phenomena, and the different sensory functions are unequally disturbed in the areas corresponding to the several nerve roots. There is sometimes a combination of hyperæsthesia on one side and anæsthesia on the other.
Retention of urine is not always present even in those cases in which the limbs are completely paralysed, as the fibres of one side of the cord are sufficient to maintain the functions of the bladder. The patient may be aware that the bladder is full, although he is unable to empty it. Similarly, sensation in the rectum and anus may be retained although the control of the sphincters is lost. Priapism may be present, but tends to disappear.