Treatment.—The general condition of the patient should be improved, by dieting and tonics. One of the most reliable methods of hastening union in these cases is by inducing passive hyperæmia of the limb after the method advocated by Bier, and this plan should always be tried in the first instance. An elastic bandage is applied above the seat of fracture, sufficiently tightly to congest the limb beyond, and, to concentrate the congestion in the vicinity of the fracture, an ordinary bandage should be applied from the distal extremity to within a few inches of the break. The hyperæmia should be maintained for several hours (six to twelve) daily. An apparatus should be adjusted to enable the patient to get into the open air, and in fractures of the lower extremity the patient should move about with crutches in the intervals, putting weight on the fractured bone. This method of treatment should be persevered with for three or four weeks, and the limb should be massaged daily while the constricting bandage is off.
Among the other methods which have been recommended are the injection between the fragments of oil of turpentine (Mikulicz), a quantity of the patient's own blood (Schmieden), or alcohol and iodine; the forcible rubbing of the ends together, under an anæsthetic if necessary; and the administration of thyreoid extract. If these methods fail, the case should be treated as one of un-united fracture. As a rule, satisfactory union is ultimately obtained, although much patience is required.
Non-Union.—Sometimes the fragments become united by a dense band of fibrous tissue, and the reparative process goes no further—fibrous union. This is frequently the case in fractures of the patella, the olecranon, and the narrow part of the neck of the femur.
False Joint—Pseudarthrosis.—In rare cases the ends of the fragments become rounded and are covered with a layer of cartilage. Around their ends a capsule of fibrous tissues forms, on the inner aspect of which a layer of endothelium develops and secretes a synovia-like fluid. This is met with chiefly in the humerus and in the clavicle.
Failure of Union—“Un-united Fracture.”—As the time taken for union varies widely in different bones, and ossification may ultimately ensue after being delayed for several months, a fracture cannot be said to have failed to unite until the average period has been long overpassed and still there is no evidence of fusion of the fragments. Under these conditions failure of union is a rare complication of fractures. In adults it is most frequently met with in the humerus, the radius and ulna ([Fig. 6]), and the femur; in children in the bones of the leg and in the forearm.
Fig. 6.—Radiogram of Un-united Fracture of Shaft of Ulna of fifteen years' duration.
In a radiogram the bones in the vicinity of the fracture, particularly the distal fragment, cast a comparatively faint shadow, and there may even be a clear space between the fragments. When the parts are exposed by operation, the bone is found to be soft and spongy and the ends of the fragments are rarefied and atrophied; sometimes they are pointed, and occasionally absorption has taken place to such an extent that a gap exists between the fragments. The bone is easily penetrated by a bradawl, and if an attempt is made to apply plates, the screws fail to bite. These changes are most marked in the distal fragment.
The want of union is evidently due to defective activity of the bone-forming cells in the vicinity of the fracture. This may result from constitutional dyscrasia, or may be associated with a defective blood supply, as when the nutrient artery is injured. Interference with the trophic nerve supply may play a part, as cases are recorded by Bognaud in which union of fractures of the leg failed to take place after injuries of the spinal medulla causing paraplegia. The condition has been attributed to local causes, such as the interposition of muscle or other soft tissue between the fragments, or to the presence of a separated fragment of bone or of a sequestrum following suppuration. In our experience such factors are seldom present.