The following are translations from Dr. Reincke’s most valuable report upon the vital statistics of Hamburg for 1892. I much regret that I am unable to reproduce in full the very complete and instructive tables and diagrams which accompany the report.

Diarrhœa and Cholera Infantum (page 10). “It is usually assumed that the increase of diarrhœal diseases in summer is to be explained by the high temperature, especially by the action of the heat upon the principal food of infants—milk. Our observations, however, indicate that a deeper cause must be sought.” (Tables and diagrams of deaths from cholera infantum by months for Hamburg and for Altona with the mean temperatures, 1871-1892.)

“From these it appears that the highest monthly mortality of each year in Hamburg occurred 7 times in July, 13 times in August, and 3 times in September, and substantially the same in Altona. If one compares the corresponding temperatures, it is found that in the three years 1886, 1891, and 1892, with high September mortalities, especially the first two of them, had their maximum temperature much earlier, in fact earlier than usual. Throughout, the correspondence between deaths and temperatures is not well marked. Repeated high temperatures in May and June have never been followed by a notable amount of cholera infantum, although such periods have lasted for a considerable time. For example, toward the end of May, 1892, for a long time the temperature was higher than in the following August, when the cholera infantum appeared.

“The following observations are still more interesting. As is seen from the diagram, in addition to the annual rise in summer there is also a smaller increase in the winter, which is especially marked in Altona. In 1892 this winter outbreak was greater than the summer one, and nearly as great in 1880 and in 1888. The few years when this winter increase was not marked, 1876-7, 1877-8, 1881-2, 1883-4, were warm winters in which the mean temperature did not go below the freezing-point. It is also to be noted that the time of this winter outbreak is much more variable than that of the summer one. In 1887 the greatest mortality was in November; in 1889 in February; in other years in December or January, and in Altona, in 1886 and 1888, in March, which is sufficient evidence that it was not the result of Christmas festivities.

“Farther, the winter diarrhœa of Hamburg and of Altona are not parallel as is the case in summer. In Hamburg the greatest mortality generally comes before New Year’s; in Altona one to two months later.

“In Bockendahl’s Generalbericht über das öffentliche Gesundheitswesen der Provinz Schleswig-Holstein für das Jahr 1870, page 10, we read: ‘Yet more remarkable was an epidemic of cholera infantum in Altona in February which proved fatal to 43 children. These cases were distributed in every part of the city, and could not be explained by the health officer until he ascertained that the water company had supplied unfiltered water to the city. This occurred for a few days only in January, and was the only time in the whole year that unfiltered Elbe water was delivered. However little reason there may be to believe that there was a connection between these circumstances, future interruptions of the service of filtered water should be most critically watched, as only in this way can reliable conclusions be reached. Without attempting to draw any scientific conclusions from the fact, I cannot do less than record that, prior to the outbreak of cholera on August 20, 1871, unfiltered together with filtered water had been supplied to the city August 11 to 18. The action of the authorities was then justified when they forbade in future the supply of unfiltered water except in cases of most urgent necessity, as in case of general conflagration; and in such a case, or in case of interruption due to broken pipes, that the public should be suitably warned.’

“The author of this paragraph, Dr. Kraus, became later the health officer of Hamburg, and in an opinion written by him in 1874, and now before me, he most earnestly urged the adoption of sand-filtration in Hamburg, and cites the above observations in support of his position. In the annual report of vital statistics of Hamburg for 1875 he says that it is quite possible that the addition of unfiltered Elbe water to milk is the cause of the high mortality from cholera infantum, as compared with London, and this idea was often afterward expressed by him. Since then so much evidence has accumulated that his view may fairly be considered proved.

“For the information of readers not familiar with local conditions, a mention of the sources of the water-supplies up to the present time used by Hamburg and Altona will be useful. Both cities take their entire water-supplies from the Elbe—Altona from a point about 7 miles below the discharge of the sewage of both cities, Hamburg from about 7 miles above. The raw water at Altona is thus polluted by the sewage from the population of both cities, having now together over 700,000 inhabitants, and contains in general 20,000 to 40,000 or more bacteria per cubic centimeter. The raw water of Hamburg has, however, according to the time of year and tide, from 200 to 5000, but here also occasionally much higher numbers are obtained when the ebb tide carries sewage up to the intake. How often this takes place is not accurately known, but most frequently in summer when the river is low, more rarely in winter and in times of flood. Recent bacterial examinations show that it occurs much more frequently than was formerly assumed from float experiments. This water is pumped directly to the city raw, while that for Altona is carefully filtered.

“Years ago I expressed the opinion that the repeated typhoid epidemics in Altona stood in direct connection with disturbances of the action of the filters by frost, which result in the supply of insufficiently purified water. Wallichs in Altona has also come to this conclusion as a result of extended observation, and recently Robert Koch has explained the little winter epidemic of cholera in Altona in the same way, thus supporting our theory. When open filters are cleaned in cold, frosty weather the bacteria in the water are not sufficiently held back by the filters. Such disturbances of filtration not only preceded the explosive epidemics of typhoid fever of 1886, 1887, 1888, 1891, and 1892, and the cholera outbreaks of 1871 and 1893, but also the winter outbreaks of cholera infantum which have been so often repeated. It cannot be doubted that these phenomena bear the relation to each other of cause and effect. It is thus explained why in the warm winters no such outbreaks have taken place, and also why the cholera infantum in winter is not parallel in Hamburg and Altona.