Against this mad intrigue one clear-headed individual resolutely set himself—not wholly from disinterested motives. Alexander Hamilton had good reason to know Burr. He declared in private conversation, and the remark speedily became public property, that he looked upon Burr as a dangerous man who ought not to be trusted with the reins of government. He pleaded with New York Federalists not to commit the fatal blunder of endorsing Burr in caucus, and he finally won his point; but he could not prevent his partisans from supporting Burr at the polls.

The defeat of Burr dashed the hopes of the Federalists of New England; the bubble of a Northern Confederacy vanished. It dashed also Burr's personal ambitions: he could no longer hope for political rehabilitation in New York. And the man who a second time had crossed his path and thwarted his purposes was his old rival, Alexander Hamilton. It is said that Burr was not naturally vindictive: perhaps no man is naturally vindictive. Certain it is that bitter disappointment had now made Burr what Hamilton had called him—"a dangerous man." He took the common course of men of honor at this time; he demanded prompt and unqualified acknowledgment or denial of the expression. Well aware of what lay behind this demand, Hamilton replied deliberately with half-conciliatory words, but he ended with the usual words of those prepared to accept a challenge, "I can only regret the circumstance, and must abide the consequences." A challenge followed. We are told that Hamilton accepted to save his political leadership and influence—strange illusion in one so gifted! Yet public opinion had not yet condemned dueling, and men must be judged against the background of their times.

On a summer morning (July 11, 1804) Burr and Hamilton crossed the Hudson to Weehawken and there faced each other for the last time. Hamilton withheld his fire; Burr aimed with murderous intent, and Hamilton fell mortally wounded. The shot from Burr's pistol long reverberated. It woke public conscience to the horror and uselessness of dueling, and left Burr an outlaw from respectable society, stunned by the recoil, and under indictment for murder. Only in the South and West did men treat the incident lightly as an affair of honor.

The political career of Burr was now closed. When he again met the Senate face to face, he had been dropped by his own party in favor of George Clinton, to whom he surrendered the Vice-Presidency on March 5, 1805. His farewell address is described as one of the most affecting ever spoken in the Senate. Describing the scene to his daughter, Burr said that tears flowed abundantly, but Burr must have described what he wished to see. American politicians are not Homeric heroes, who weep on slight provocation; and any inclination to pity Burr must have been inhibited by the knowledge that he had made himself the rallying-point of every dubious intrigue at the capital.

The list of Burr's intimates included Jonathan Dayton, whose term as Senator had just ended, and who, like Burr, sought means of promoting his fortunes, John Smith, Senator from Ohio, the notorious Swartwouts of New York who were attached to Burr as gangsters to their chief, and General James Wilkinson, governor of the northern territory carved out of Louisiana and commander of the western army with headquarters at St. Louis.

Wilkinson had a long record of duplicity, which was suspected but never proved by his contemporaries. There was hardly a dubious episode from the Revolution to this date with which he had not been connected. He was implicated in the Conway cabal against Washington; he was active in the separatist movement in Kentucky during the Confederation; he entered into an irregular commercial agreement with the Spanish authorities at New Orleans; he was suspected—and rightly, as documents recently unearthed in Spain prove—of having taken an oath of allegiance to Spain and of being in the pay of Spain; he was also suspected—and justly—of using his influence to bring about a separation of the Western States from the Union; yet in 1791 he was given a lieutenant-colonel's commission in the regular army and served under St. Clair in the Northwest, and again as a brigadier-general under Wayne. Even here the atmosphere of intrigue enveloped him, and he was accused of inciting discontent among the Kentucky troops and of trying to supplant Wayne. When commissioners were trying to run the Southern boundary in accordance with the treaty of 1795 with Spain, Wilkinson—still a pensioner of Spain, as documents prove—attempted to delay the survey. In the light of these revelations, Wilkinson appears as an unscrupulous adventurer whose thirst for lucre made him willing to betray either master—the Spaniard who pensioned him or the American who gave him his command.

In the spring of 1805 Burr made a leisurely journey across the mountains, by way of Pittsburgh, to New Orleans, where he had friends and personal followers. The secretary of the territory was one of his henchmen; a justice of the superior court was his stepson; the Creole petitionists who had come to Washington to secure self-government had been cordially received by Burr and had a lively sense of gratitude. On his way down the Ohio, Burr landed at Blennerhassett's Island, where an eccentric Irishman of that name owned an estate. Harman Blennerhassett was to rue the day that he entertained this fascinating guest. At Cincinnati he was the guest of Senator Smith, and there he also met Dayton. At Nashville he visited General Andrew Jackson, who was thrilled with the prospect of war with Spain; at Fort Massac he spent four days in close conference with General Wilkinson; and at New Orleans he consorted with Daniel Clark, a rich merchant and the most uncompromising opponent of Governor Claiborne, and with members of the Mexican Association and every would-be adventurer and filibuster. In November, Burr was again in Washington. What was the purpose of this journey and what did it accomplish?

It is far easier to tell what Burr did after this mysterious western expedition than what he planned to do. There is danger of reading too great consistency into his designs. At one moment, if we may believe Anthony Merry, the British Minister, who lent an ear to Burr's proposals, he was plotting a revolution which should separate the Western States from the Union. To accomplish this design he needed British funds and a British naval force. Jonathan Dayton revealed to Yrujo much the same plot—which he thought was worth thirty or forty thousand dollars to the Spanish Government. To such urgent necessity for funds were the conspirators driven. But Dayton added further details to the story which may have been intended only to intimidate Yrujo. The revolution effected by British aid, said Dayton gravely, an expedition would be undertaken against Mexico. Subsequently Dayton unfolded a still more remarkable tale. Burr had been disappointed in the expectation of British aid, and he was now bent upon "an almost insane plan," which was nothing less than the seizure of the Government at Washington. With the government funds thus obtained, and with the necessary frigates, the conspirators would sail for New Orleans and proclaim the independence of Louisiana and the Western States.

The kernel of truth in these accounts is not easily separated from the chaff. The supposition that Burr seriously contemplated a separation of the Western States from the Union may be dismissed from consideration. The loyalty of the Mississippi Valley at this time is beyond question; and Burr was too keen an observer not to recognize the temper of the people with whom he sojourned. But there is reason to believe that he and his confederates may have planned an enterprise against Mexico, for such a project was quite to the taste of Westerners who hated Spain as ardently as they loved the Union. Circumstances favored a filibustering expedition. The President's bellicose message of December had prepared the people of the Mississippi Valley for war; the Spanish plotters had been expelled from Louisiana; Spanish forces had crossed the Sabine; American troops had been sent to repel them if need be; the South American revolutionist Miranda had sailed, with vessels fitted out in New York, to start a revolt against Spanish rule in Caracas; every revolutionist in New Orleans was on the qui vive. What better time could there be to launch a filibustering expedition against Mexico? If it succeeded and a republic were established, the American Government might be expected to recognize a fait accompli.

The success of Burr's plans, whatever they may have been, depended on his procuring funds; and it was doubtless the hope of extracting aid from Blennerhassett that drew him to the island in midsummer of 1806. Burr was accompanied by his daughter Theodosia and her husband, Joseph Alston, a wealthy South Carolina planter, who was either the dupe or the accomplice of Burr. Together they persuaded the credulous Irishman to purchase a tract of land on the Washita River in the heart of Louisiana, which would ultimately net him a profit of a million dollars when Louisiana became an independent state with Burr as ruler and England as protector. They even assured Blennerhassett that he should go as minister to England. He was so dazzled at the prospect that he not only made the initial payment for the lands, but advanced all his property for Burr's use on receiving a guaranty from Alston. Having landed his fish, Burr set off down the river to visit General Jackson at Nashville and to procure boats and supplies for his expedition.