Iodids.—The salts of iodin—potassium, sodium, ammonium iodid—resemble each other in their action and uses. They are used as alteratives in constitutional diseases, like chronic rheumatism and gout, as absorbents of exudates in chronic inflammatory diseases, and as eliminants in chronic mineral poisoning. Their continued use occasions a group of symptoms—frontal headache, nasal discharge, sore throat, and a cutaneous eruption—termed iodism. The dose is from 5 to 30 grains (0.3-2 gm.), well diluted, after meals.
Iodoform.—This drug owes its virtues to iodin, of which it contains about 50 per cent. When brought into contact with raw surfaces it exerts a mild anesthetic effect, liberates its iodin, and thereby acts as an antiseptic. When applied too freely it may be absorbed and cause toxic effects—headache, elevation of temperature, restlessness, a diffuse red rash on the face and limbs, delirium, stupor, and collapse. The unpleasant odor of the drug can be removed from the hands and from instruments by oil of turpentine.
Ipecac.—This drug is used as an emetic and expectorant. As an emetic it is safe, but somewhat slow in action. It is especially useful in the young and feeble, as it causes but little depression.
The dose of powdered ipecac, as an emetic, is from 20 to 30 grains (1.2-2 gm.); of the Syrup (Syrupus Ipecacuanhæ), as an expectorant, from 10-60 minims (0.6-4 c.c.); as an emetic, from 2 to 4 drams (8-15 c.c.); of the wine, as an expectorant, from 10 to 30 minims (0.6-1.8 c.c.); as an emetic, 1 dram (4 c.c.).
Iron. (Ferrum).—The various preparations of iron are employed as tonics and astringents. As tonics, they are especially indicated in simple anemia; as astringents they are employed locally in bleeding, and, internally, in diarrhea.
The dose of Reduced Iron (Ferrum Reductum) is from 1 to 5 grains (0.06-0.3 gm.); of the Pills of Iron Carbonate or Blaud’s Pills (Pilulæ Ferri Carbonatis), 1 to 3 pills; of the Tincture of Ferric Chlorid (Tinctura Ferri Chloridi), 5 to 10 minims (0.3-0.6 c.c.); of the Solution of Iron and Ammonium Acetate or Basham’s Mixture (Liquor Ferri et Ammonii Acetatis), 1 to 4 drams (4-15 c.c.); of the Sulphate of Iron (Ferri Sulphas), 1-3 grains (0.06-0.2 gm.); of the Syrup of Iodid of Iron (Syrupus Ferri Iodidi), 5 to 60 minims (0.3-4 c.c.). The Solution of Iron Subsulphate (Monsel’s solution) is used only as a hemostatic, and Iron Hydrate with Magnesia as an antidote in arsenic-poisoning. The dose of the latter is a tablespoonful every ten to fifteen minutes.
Lead.—The preparations of lead are used internally and externally as sedatives and astringents. Lead Acetate (Plumbi Acetas) is employed internally in diarrhea. The dose is from 1 to 3 grains (0.06-0.2 gm.), in pill form.
The Solution of Lead Subacetate (Liquor Plumbi Subacetatis) is employed externally. Diluted with from 5 to 6 parts of water it is used as a sedative application in ivy-poisoning and erysipelas.
The Dilute Solution of Lead Subacetate (Liquor Plumbi Subacetatis Dilutus) is known as lead-water, and is chiefly employed in making the sedative preparation known as lead-water and laudanum. As usually dispensed it contains 1 dram (4 c.c.) of laudanum and 4 drams (15 c.c.) of lead-water to 2 ounces (60 c.c.) of water.
Acute lead-poisoning is characterized by a burning pain in the abdomen, a metallic taste in the mouth, vomiting, purging, coma, and collapse.