Henry was bent upon obtaining his divorce from Queen Katherine; but though he had obtained many fair promises from Rome, he had failed to induce the then Pontiff, Clement II., to do anything towards advancing his suit. It was in the highest degree expedient, therefore, to send a delegate to Rome who was not only a wary diplomatist, but also a shrewd and skilful lawyer; above all, he must be one in whom the King could fully confide. In Gardiner were found all these essential qualifications, and the King did not hesitate to inform the Cardinal of the favourable impression his secretary had made.

With all his faults, there was nothing mean in the character of Wolsey. He was truly great in this particular, that he feared no man's rise, and grudged to none the reward due to talent. Though overbearing in temper, haughty in manner, tyrannical and revengeful in action, it was yet this noble quality that so strongly attached his adherents to him.

Far from viewing with displeasure the favourable impression made upon the King, he aided his secretary's interests with all his powerful influence; and in February, 1528, Gardiner, together with Dr. Fox, Provost of King's College, Cambridge, left England on a special mission to Rome.

It is evident, from many documents still extant, that the entire confidence, both of the King and of his Minister, had been reposed in Gardiner.

Respecting his conduct in Rome, historians are again at variance as to his motives; but all agree in praising his talents, his dexterity, and his diligence.

Some writers assert that he honestly endeavoured to carry out the King's and the Cardinal's wishes; others, on the contrary, maintain that, in order to secure his own advancement, he betrayed the Cardinal in this embassy, and that for this end he urged forward with the greatest eagerness proceedings which he knew his master in his heart desired might be spun out as lengthily as possible.

However, it must be admitted that such statements are barely compatible with the affection which Wolsey ever entertained for his secretary.

When writing to Gardiner, the Cardinal calls him "the half of himself, than whom none was dearer to him;" and in recommending him to the Pope, he says, when His Holiness hears him speak, it will be as if he heard the Cardinal himself.

At any rate Gardiner spoke boldly at Rome. His diligence and activity also were so great, that between the conflicting interests and exertions of the various Courts of England, France, Spain, and Austria, the unfortunate Pontiff was so pressed and harassed that he fell dangerously ill.