In 1875, in his Traitement rationnel de la phthisie pulmonaire, Dr. de Pietra Santa said, page 394:

"Among the most renowned practitioners of Paris, Péan, Barth, G. Sée, and Cabrol have promptly adopted the preparations of Coca. Ch. Fauvel prescribes it in affections of the respiratory passages. It is in these diseases that I, too, have had occasion to advise its daily use in the most convenient, the most agreeable, and the most active form—that of the Vin Tonique de Mariani."

Thus has been realized Réveil's prediction: "This substance (Coca) is destined to take an important rank in therapeutics."

In the Revue de Thérapeutique médicaux-chirurgicale, June 11, 1876, page 381. Bibliographie: Dictionnaire Encyclopédique des sciences médicales, par A. Dechambre, Dr. H. Cottin thus closes his article:

"In France, we are using a great deal of Coca wine, and it is tending to take the place of all other tonic wines; it is borne a longer time by the stomach and is more agreeable to the palate. M. Mariani has contributed much to the popularization of Coca by the perfection of his preparations, vin, thé élixir and pâte. These are the forms at present most employed."

Dr. Chapusot, of Paris, thus sums up his personal observations: "A claret-glass of this wine has always been enough to make me forget hunger and to sustain my strength; I have felt a grateful warmth and a general exaltation of the economy; the digestion of the following meal has always been easier than if I had not taken the Vin Mariani, and, although I had not such a ravenous appetite as if I had gone without it, I ate a good deal, the stomach appearing stronger and more active."

It was Dr. Ch. Fauvel who gave our wine the very striking and exact title of "Tensor of the vocal cords." He says: "Thanks to Vin Mariani, I have been able to restore the voice of many lyric artists who would have been unable without this potent agent to give their performances."

Dr. J. Leonard Corning, in Brain Exhaustion, New York, 1884, pages 78 and 112, says: "Of all the medicaments that I employ in the very numerous cases of irritability, Vin Mariani has rendered the greatest service. I do not except even the bromides, for this preparation of Coca possesses the calmative properties of those salts without producing the unpleasant depression which characterizes them."

The same author continues: