"I have also used Vin Mariani to save smokers of exaggerated habits, from nicotinism. A few glasses of Vin Mariani taken in small doses, either pure or mixed with water, acted as a substitute for pipes and cigars, because the smokers found in it the cerebral excitement which they sought in tobacco, wholly preserving their intellectual faculties.
"I have also employed it with success for chronic bronchitis and pulmonary phthisis. Vin Mariani increases the appetite and diminishes the cough in these two morbid states.
"To combat the cough I give it mixed with water in the form of tisane, a Bordeaux-glass of Mariani in a glass of hot water.
"Besides I have used it to the greatest advantage in convalescence from typhoid fever, when no wine, not even Bordeaux, was retained by the stomach on account of gastric irritation which is the rule after fevers of this nature.
"Although I have confined myself to giving but a rapid glance at the results that I have obtained, I have the statistics, which I keep in reserve should they be needed.
"I can certify that Vin Mariani is the most powerful weapon that can be put in the hands of military physicians to combat the diseases, the infirmities, and even the vicious habits engendered by camp life and the servitude of military existence."
Dr. Villeneuve, among other cases of morphinomania conquered by the combined use of the pâte and the Vin Mariani, communicated to us in 1884 the following observation:
"M. X...., barrister, 32 years of age, five years ago began to use morphine preparations as a remedy against a very alarming chronic bronchitis and granulations in the throat, which were irritated constantly by cigarette smoking.
"The patient at first only used morphine, but his physicians committed the imprudence of treating him by hypodermic injection. A notable change for the better was produced during the first month, but, unfortunately, abuse succeeded promptly the use of the medicament—so much so that when I commenced to treat the patient, he was taking daily from 1 gramme 50 centigrammes to 1 gramme 80 centigrammes of morphine hypodermically. When he was four hours without his dose there appeared insomnia, hallucinations and delirium; constipation lasting sometimes for fifteen days, which brought on in the spring a very alarming perityphlitis, jerking of the muscles, sudden frights, dyspepsia, and at last frightful congestion of the face whenever he drank a drop of wine or brandy.
"After a month's treatment I had succeeded in reducing the daily doses without causing alarming symptoms; the physiological functions seemed to awaken again. However, the congestion and especially the dyspepsia was very grave, and the cough which had been suppressed by morphine returned. It was then that I treated my patient with phosphate of lime, the pâte and the Vin Mariani. Lacking his habitual stimulant, he was plunged in a semi-coma from which he could not always be relieved with weaker daily doses of morphine.