But the Germans by this time were in full flight before the Duke of Guise, and Vendôme and Tremouille manœuvred more menacingly on the front and flank of the Allies. Tremouille, in particular, grew more and more audacious, beat up their quarters with his cavalry, harassed them by frequent skirmishes, and intercepted their convoys. The position of the allied troops became every day more critical. They were threatened with a growing force in their rear, drawn from the garrisons of Picardy, and there was danger of their supplies, which were all derived from Calais, being cut off. The troops were become sickly, and discontented with their situation. It was high time to retrace their steps, and they commenced their march by way of Valenciennes. But the weather was very rainy, the roads were almost impassable, cold and frost succeeded, and the sickness and murmurs of the troops augmented every day. Numbers perished on the march; all were eager to reach their homes; and, as the Flemings drew near their frontiers, they deserted in shoals. The armies then separated, and Suffolk reached Calais in December, with his forces greatly reduced, and all in miserable condition.

On the 14th of September, whilst the Duke of Suffolk was advancing on Paris, an event occurred which arrested the attention of Cardinal Wolsey even more than the engrossing moves on the great chess-board of war. This was the death of the Pope Adrian. He had occupied the papal chair only about twenty months; and so impatient were the Italians of the Flemish pope and his strict economy, that they styled the doctor who attended him in his last sickness the "saviour of his country." Wolsey lost no time in putting in his claim; and wrote to Dr. Clark, the English ambassador at Rome, telling him to spare neither money nor promises, for that it was by command of the king, who would undoubtedly see all his engagements performed. This time Wolsey was put in nomination, and obtained a considerable number of votes; but there was no real chance for him, for the Italians were clamorous to have no more ultramontane, or, as they styled them, barbarian popes. Charles V., despite his promises to Wolsey, not only did not move a finger in his favour, but threw all his influence into the scale to carry the election of Julius de Medici; whilst the French cardinals, to a man, were opposed to Wolsey as the most dangerous enemy to their sovereign. The conclave met in October, and the discussion was continued through six stormy weeks. The election at length was seen to lie between Jacovaccio Romano and Julius de Medici. Cardinal Pompeo Colonna, who held the most decisive influence in the conclave, threw his weight into the scale for Romano, and the balance hung undecided; but all at once it gave way. Colonna, although he hated the Medici, gave up his opposition, and Julius was unanimously elected.

Wolsey, to all appearance, bore this second disappointment with the equanimity of a philosopher; yet we may justly imagine that it produced a deep change in his feelings towards the emperor, and led to a hostile policy against his interests and those of Queen Catherine, his aunt, in England. But Wolsey had prepared for either event, his election or rejection; and the moment the latter became certain, the whole of the influence of the English Government was employed in favour of the election of Julius de Medici. On the strength of this, the English ambassadors congratulated Julius on his elevation, and solicited the continuance of the legatine commission to Wolsey. The Pope, who assumed the name of Clement VII., not only renewed the commission, but granted it for life, with augmented powers; and added to it a commission to reform or suppress certain religious houses in England. This was a dangerous power, and as Wolsey, in 1525—only two years afterwards—by this authority suppressed a number of monasteries, it is by no means improbable that it led Henry to think of those more sweeping changes of the same kind which he afterwards effected. The money thus procured was devoted, notwithstanding the necessities of the State, to the erection of colleges, where both Wolsey and his master declared they were anxious to educate able men in order to oppose effectually the fast-growing heresies of Martin Luther.

The campaign in Italy opened in the spring of 1524, with wonderfully increased difficulties for the French. Charles V. had appointed the renegade Duke of Bourbon his generalissimo in that country against his own sovereign and compatriots. Henry of England engaged to furnish 100,000 crowns for the first month's pay of the duke's army, and to make a diversion by invading Picardy in July. The emperor promised to defray the cost of the Italian army for the remainder of the campaign, and to invade Languedoc at the same time. Thus supported, Bourbon took the field early in the spring; and by the end of May the duke had completely freed Italy of his countrymen, and driven them across the Alps. The losses of the French in this retreat were dreadful, and perhaps the greatest calamity was the death of the famous Chevalier Bayard, the knight "sans peur et sans reproche," who was killed as he was protecting the rear of the army, on the banks of the Sesia (April 30, 1524.)

Bourbon, ardent and impatient to secure the kingdom which had been promised him in France, as well as thirsting with desire to take the utmost vengeance on Francis I., entreated the emperor to allow him to quit Italy and enter France with his victorious army. The emperor consented, and the Imperial forces soon found themselves descending from the Alps. Unfortunately, Charles had divided the command of this expedition between Bourbon and the Marquis of Pescara, and the certain result was divided councils. Bourbon urged to push forward to Lyons, calculating on his friends and dependants in France flocking to him there; but Pescara had probably different instructions, and accordingly advised that they should descend on Provence, and lay siege to Marseilles. This was palpably the suggestion of the emperor, for he was ambitious of securing Marseilles, and holding it as a key to the south of France, as Calais was to the north, in the hands of the English. Thither, therefore, they marched, entered Provence on the 2nd of July, and on the 19th of August they sat down before Marseilles with an army of 16,000 men.

But the situation of the Imperial troops soon became extremely hazardous there. The place was strongly fortified; it contained a garrison of 3,200 men, and these were zealously supported by 9,000 of the inhabitants, who, detesting the Spaniards, took up arms and fought most gallantly. Bourbon and Pescara spent forty days in mining and bombarding the place, when they became aware of a tempest gathering which boded their utter destruction. This was Francis marching from Avignon at the head of 40,000 men. Neither Henry nor the emperor had made those diversions in Languedoc and Picardy which they had promised, and thus the whole weight of the army of France was at liberty to descend upon them. Bourbon and Pescara precipitately abandoned the siege, made for the Alps, and regained Italy.

At this moment Francis committed a military error, which probably deprived him of the triumph of thoroughly routing his enemies. To have continued the pursuit was almost certain to have destroyed the Imperialist force, for it was worn down by its severe marches, and the road to Lodi by which Pescara retreated was actually strewn with his exhausted horses. The army of Pescara was the sole Imperial force now in Italy, and its defeat would have been the immediate recovery of the Milanese territory. But Francis was beguiled into the delay of besieging Pavia, in which Pescara had left a strong garrison, under Antonio da Leyva. Pavia was a well-fortified city, situated on the deep and rapid Ticino, in a peculiarly strong position, and had repeatedly defied armies for a long time together, particularly those of the Lombards and of Charlemagne. The moment Pescara heard of Francis sitting down before it, he exclaimed that he was saved! Every exertion was made by the Imperialists to profit by the time thus given them. The Duke of Bourbon hastened over the Alps to Germany to raise 12,000 men, for which purpose he had pawned his jewels. Lannoy, the viceroy of Naples, pledged the regular revenues of that kingdom for ready cash for the hiring of troops, and great activity was displayed in raising an army and posting it betwixt the Adda and the Ticino.

For three months Francis continued lying before Pavia, and committed the further error of weakening his forces, by detaching 6,000 of them, under Albany, the late regent of Scotland, to menace the kingdom of Naples.

In the beginning of February, 1525, the Imperialist generals thought themselves strong enough to attack the French in their entrenchments. These entrenchments were very formidable. The rear-guard was posted in the beautiful castle of Mirabello, in the midst of an extensive park, enclosed by high and solid walls. But Leyva, who commanded the garrison, found means to communicate with the Imperial generals outside, and he sent them word that they must either relieve him or that he must attempt to cut his way out, for famine was urgent amongst his troops. The generals themselves were suffering from want of provisions and pay for their troops. In the French camp the wisest commanders counselled Francis to raise the siege and retire to Milan, confident that the enemy must soon disband from want of pay. But Bonivet treated this counsel as mean and dastardly; and, unfortunately, this was the tone most likely to captivate the chivalrous mind of the French king. He resolved to stand his ground.

On the 24th of February, Bourbon, Pescara, and Lannoy, having distracted the attention of the French for several days previously by false attacks, at midnight led out their troops silently to the park. A body of pioneers commenced operations on the wall, and before daylight they had effected a breach of a hundred paces in length, and at dawn they carried the castle by surprise. Francis drew his troops out of their entrenchments and made a push across the Ticino, but he found the bridge demolished, and a strong body of the Spaniards closely drawn up on the banks. Attacked fiercely by the garrison in the rear, and hemmed in by the Imperial army in front, the battle became desperate. Francis had his horse killed under him; the Swiss, contrary to their wont, turned and fled at the first charge; and the Germans, who fought with singular valour, were annihilated to a man. The Spanish musketeers then broke the French ranks; and the king, being already wounded twice in the face, and once in the hand, refused to surrender to the Spaniards who environed him. Fortunately, Pomperant, a French gentleman in the service of the Duke of Bourbon, recognised him, and called Lannoy, to whom the king resigned his sword. Lannoy, kneeling, kissed the king's hand, took the sword, and gave him his own in return, saying it did not become a monarch to appear unarmed in the presence of a subject. The king was relieved of his helmet by James D'Avila; and the Spanish soldiers, who admired his valour, came crowding around him, and snatched the feathers from it, and, when they were all gone, even cut pieces from his clothes, to keep as memorials that they had fought hand to hand with him. Francis was soon left standing in his jerkin and hose, and, despite his misfortune, could not help laughing at his situation, and at the eagerness of the soldiers for something belonging to him.