Lord Campbell: We have intimated that that is our clear opinion.

Mr. Rogers, examined by Mr. Gray: I am Professor of Chemistry at St. George’s School of Medicine, in London. I have made experiments upon one animal (a dog) poisoned by strychnia. The experiments commenced at the close of last December, and ended about ten days since. I gave it two grains of pure strychnia in meat. Three days after death I removed the stomach and contents, and some of the blood. The blood became putrid in about 10 days, and I then analysed it with a view to find strychnine. I separated the strychnine by colour tests. I cannot say how much it was by weight. In a month or five weeks, when the matter had putrefied, I analysed the stomach and its contents. I treated it with acidulated distilled water, and succeeded in discovering strychnia in large quantities about 10 days ago. I never analysed a human subject with a view to find strychnia, but I have many times done so to find other poisons. Strychnia must unquestionably have been discovered in this case if it had been present and the proper tests had been used.

Cross-examined by the Attorney-General: I have only made one experiment. If the contents of the stomach were lost it would make a difference, but not if they were only shaken up. The operation would then be more difficult. I am a medical man. I did not analyse the tissues of the body of the dog. If I had tried the tissues of Cook’s body it might have been found if it was there, notwithstanding the time that had elapsed since he died. I don’t say that the time would prevent its discovery if there.

Re-examined by Mr. Gray: If strychnia were in the stomach a portion would probably be smeared over the mucous membrane, and then I should expect to find it on the surface.

Dr. Henry Letheby, examined by Mr. Kenealy: I am a Bachelor of Medicine, Professor of Chemistry and Toxicology in the London Hospital of Medicine, and Medical Officer of Health to the City of London. I have been engaged for a considerable time in the study of poisons and their action on the living animal economy. I have also been frequently engaged on behalf of the Crown in prosecutions in cases of this nature during the last 14 years. I have been present during the examination of the medical witnesses, and have attended to the evidence as to the symptoms which have been described as attending the death of Cook. I have witnessed many cases of animals poisoned by strychnine, and many cases of poisoning by nux vomica in the human body, one of which was fatal. The symptoms described in this case do not accord with the symptoms I have witnessed in the case of those animals. They differ in this respect:—In the first place I never witnessed the long interval between the administration of the poison and the commencement of the symptoms which is said to have elapsed in this case. The longest interval I have known has been three-quarters of an hour, and then the poison was administered under most disadvantageous circumstances. It was given on a very full stomach and in a form uneasy of solution. I have seen the symptoms begin in five minutes. The average time in which they begin is a quarter of an hour. In all cases I have seen the system has been in that irritable state that the very lightest excitement, such as an effort to move, a touch, a noise, a breath of air, would send the patient off in convulsions. It is not at all probable that a person, after taking strychnia, could pull a bell violently. Any movement would excite the nervous system, and bring on spasms. It is not likely that a person in that state could bear to have his neck rubbed. When a case of strychnia does not end fatally, the first paroxysm is succeeded by others, gradually shaded off, the paroxysms becoming less violent every time, and I agree with Dr. Christison that they would subside in 12 or 16 hours. I have no hesitation in saying that strychnine is of all poisons, either mineral or vegetable, the most easy of detection. I have detected it in the stomach of animals in numerous instances, also in the blood and in the tissues. The longest period after death in which I have detected it is about a month. The animal was then in a state of decomposition. I have detected very minute portions of strychnia. When it is pure the 20,000th part of a grain can be detected. I can detect the tenth part of a grain, most easily in a pint of any liquid, whether pure or putrid. I gave one animal half a grain, and I have the strychnia here now within a very small trifle. I never failed to detect strychnine where it had been administered. I have made post-mortem examinations on various animals killed by it. I have always found the right side of the heart full. The reason is that the death takes place from the fixing of the muscles of the chest by spasms, so that the blood is unable to pass through the lungs, and the heart cannot relieve itself from the blood flowing to it, but therefore becomes gorged. The lungs are congested and filled with blood. I have administered strychnia in a liquid and a solid form; I agree with Dr. Taylor that it may kill in 6 or 11 minutes when taken in a solid state in the form of a pill or bolus. I also agree with him that the first symptom is that the animal falls on its side, the jaws are spasmodically closed, and the slightest touch produces another paroxysm. But I do not agree with him that the colouring tests are fallacious. I do not agree that it is changed when it is absorbed into the blood, but I agree with its absorption. I think it is not changed when the body is decomposed. The shaking about of the contents of the stomach with the intestines in a jar would not prevent the discovery of strychnia if it had been administered. Even if the contents of the stomach were lost the mucous membrane would, in the ordinary course of things, exhibit traces of strychnia. I have studied the poison of antimony. If a quantity had been introduced into brandy and water, and swallowed at a gulp, the effect would not be to burn the throat. Antimony does not possess any such quality as that of immediate burning. I have turned my attention to the subject of poison for 17 or 18 years.

Cross-examined by the Attorney-General: I am not a member of the College of Physicians or of Surgeons. I do not now practise. I have been in general practice for two or three years. I gave evidence in the last case of this sort, tried in this court in 1851. I gave evidence of the presence of arsenic. The woman was convicted. I stated that it had been administered within four hours of death. I was the cause of her being respited, and the sentence was not carried into effect, in consequence of a letter I wrote to the Home Office. Other scientific gentlemen interfered, and challenged the soundness of my conclusions before I wrote that letter. I have not since been employed by the Crown.

By Mr. Justice Cresswell: I was present at the trial. I perfectly remember it.

Cross-examination continued: I detected the poison. I said in my letter that I could not speak as to possibilities, but merely as to probabilities. I have experimented on animals for a great number of years: on five recently. I have never given more than a grain, and it has always been in a solid form—in pills or bread. In the case where poison was administered under disadvantageous circumstances, it was kneaded up into a hard mass of bread.

Mr. Baron Alderson: Did the animal bolt it or bite it?

Witness: I opened the mouth and put it into the throat. About half an hour elapsed before the symptoms appeared in one case in which half a grain had been given. In another case death took place within 13 minutes. I have noticed twitching of the ears, difficulty of breathing, and other premonitory symptoms. There are little variations in the order in which the symptoms occur. I have known frequent instances in which an animal has died in the first paroxysm. I heard the evidence of Mrs. Smyth’s death, and I was surprised at her having got out of bed when the servant answered the bell. It is not consistent with the cases I have seen. That fact does not shake my opinion. I have no doubt that Mrs. Smyth died from strychnine. Cook’s sitting up in the bed and asking Jones to ring the bell is inconsistent with what I have observed in strychnine cases.