We are indebted to Dr Lionel Beale for these illustrations, which are taken from his very interesting work on ‘Disease Germs.’
Hiller’s experiments tend to show that putrefaction is independent of the presence of bacteria, that bacteria can develop in liquids such as urine without producing its decomposition, and that the degree of their development and the rate of their multiplication depend upon the amount of assimilable material.
The following is the definition given to the word ‘microzyme’ (which occurs above) by its originator, Dr Sanderson: “I proposed the word ‘microzyme’ as a convenient general term for the first organic forms which present themselves in organic nitrogenous liquids when about to undergo spontaneous decomposition.”
From the experiments of Béchamp it appears that under some circumstances the mother of vinegar, a conglomeration of microzymes, can be transformed into bacteria, and under other circumstances into a cellular ferment which can excite normal alcoholic fermentation in cane sugar. Subsequent researches have shown that the converse of this is also true, and that the cellular ferment may be transformed into microzymes and bacteria.
A mixture of starch and yeast kept at a temperature of 24° to 35° soon liquefies, and the yeast undergoes remarkable changes. The cells swell, become transparent, and gradually disappear. Myriads of microzymes of great agility spring into existence, then vibrios appear, and as these increase the microzymes diminish. The vibrios in their turn are succeeded by myriads of bacteria, and finally the bacteria disappear, leaving nothing but microzymes, single or coupled together. During these changes a small quantity of gas is disengaged, no butyric acid is formed, and but little acetic or lactic acids.
As then the mother of vinegar when changed into bacteria becomes lactic or butyric ferment, and when transformed into cellular matter becomes alcoholic ferment, and as beer yeast becomes lactic or butyric ferment when reduced to microzymes, vibrios, or bacteria, it is evident that the property of being a ferment of any particular nature does not depend essentially upon the nature of the ferment, but upon its organisation or structure.
A contributor to the ‘Medical Times and Gazette’ of February 2nd, 1878, advances the opinion that many of the bacteria are only parts of a plant which has other forms and other modes of growth and propagation when not confined to the living organism or to fluids, and regards the bacterium as a transitional or provisional and not as a permanent form, but an abnormal phase of life thrust upon the plant by accident.
BACTERIA AS ORIGINATORS OF DISEASE.—The researches of many eminent microscopists and physiologists afford abundant evidence of the presence of bacteria in the blood of persons affected with various infectious diseases. For instance, Core and Feltz, of Strasbourg, found a linked bacterium in the blood of those attacked with septicæmia, typhoid, and puerperal fevers. The same investigators also discovered bacteria in the blood of patients suffering from scarlet fever; this blood when injected into the veins of rabbits set up a feverish disease that proved fatal.
Again, in the blood of man and the sheep attacked with smallpox, a bacterium of the globular or sphere-shaped variety was found by Keber, Hallier, and Zurn.