11. Great and exquisite sensibility in the sense of feeling coming on near the close of the fever.

12. Acute pains in the back and limbs.

13. The appearance of an inflammatory spot on a finger or toe, Dr. H. M'Clen says, is favourable. It appears, the doctor says, as if the cause of the fever had escaped by explosion.

Signs of great danger, and of an unfavourable issue of the yellow fever are,

1. An attack of the fever, suddenly succeeding great terror, anger, or the intemperate use of venery, or strong drink.

2. The first paroxysm coming on without any premonitory symptoms, or a chilly fit.

3. A coldness over the whole body without chills for two or three days.

4. A sleepiness on the first and second days of the fever.

5. Uncommon paleness of the face not induced by blood-letting.