5. Old age. The increase of appetite in old people, their inability to use sufficient exercise, whereby their blood-vessels become relaxed, plethoric, and excitable, and above all, the translation of the strength of the muscles to the arteries, and of plethora to the veins, all indicate bleeding to be more necessary (in equal circumstances) in old, than in middle aged people. My practice in the diseases of old people has long been regulated by the above facts. I bled Mrs. Fullarton twice in a pleurisy in January, 1804, in the 84th year of her age, and thereby cured her disease. I am not the author of this practice. Botallus left a testimony in favour of it nearly 200 years ago[50], and it has since been confirmed by the experience of Hoffman, and many other physicians. An ignorance of, or inattention to this change in the state of the blood-vessels, in persons in the decline of life, and the neglect of the only remedy indicated by it, is probably the reason why diseases often prove fatal to them, which in early or middle life cured themselves, or yielded to a single dose of physic, or a few ounces of bark.
6. The time of menstruation. The uterus, during this period, is in an inflamed state, and the whole system is plethoric and excitable, and of course disposed to a violent degree of fever, from all the causes which excite it. Bleeding, therefore, is more indicated, in fever of great morbid action, at this time, than at any other. Formerly the natural discharge from the uterus was trusted to, to remove a fever contracted during the time of menstruation; but what relief can the discharge of four or five ounces of blood from the uterus afford, in a fever which requires the loss of 50, or perhaps of 100 ounces to cure it?
7. Pregnancy. The inflammation and distention induced upon the uterus directly, and indirectly upon the whole system by pregnancy, render bleeding, in the acute states of fever, more necessary than at other times. I have elsewhere mentioned the advantages of bleeding pregnant women, in the yellow fever. I did not learn the advantages of the practice in that disease. I bled Mrs. Philler 11 times in seven days, in a pleurisy during her pregnancy, in the month of March, 1783. Mrs. Fiss was bled 13 times in the spring of 1783; and Mrs. Kirby 16 times in the same condition, by my orders, in the winter of 1786, in a similar disease. All these women recovered, and the children they carried during their illness, are at this time alive, and in good health.
8. Fainting after bleeding. This symptom is accidental in many people. No inference can be drawn from it against blood-letting. It often occurs after the first and second bleedings in a fever, but in no subsequent bleeding, though it be repeated a dozen times. Of this I saw several instances, in the yellow fever of 1794. The pulse, during the fainting, is often tense and full.
9. Coldness of the extremities, and of the whole body. This cold state of fever when it occurs early, yields more readily to bleeding, than to the most cordial medicines.
10. Sweats are supposed to forbid blood-letting. I have seen two instances of death, from leaving a paroxysm of malignant fever to terminate itself by sweating. Dr. Sydenham has taught a contrary practice in the following case. “While this constitution (says the doctor) prevailed, I was called to Dr. Morice, who then practised in London. He had this fever, attended with profuse sweats, and numerous petechiæ. By the consent of some other physicians, our joint friends, he was blooded, and rose from his bed, his body being first wiped dry. He found immediate relief from the use of a cooling diet and medicines, the dangerous symptoms soon going off; and by continuing this method he recovered in a few days[51].” In the same fever, the doctor adds further, “For though one might expect great advantages in pursuing an indication taken from what generally proves serviceable (viz. sweating), yet I have found, by constant experience, that the patient not only finds no relief, but, contrariwise, is more heated thereby; so that frequently a delirium, petechiæ, and other very dangerous symptoms immediately succeed such sweats[52].”
Morgagni describes a malignant fever which prevailed in Italy, in which the patients died in profuse sweats, while their physicians were looking for a crisis from them. Bleeding would probably have checked these sweats, and cured the fever.
11. Dissolved blood, and an absence of an inflammatory crust on its crassamentum. I shall hereafter place dissolved blood at the highest point of a scale, which is intended to mark the different degrees of morbid action in the system. I have mentioned, in the Outlines of a Theory of Fever, that it is the effect of a tendency to a palsy, induced by the violent force of impression upon the blood-vessels. This appearance of the blood in certain states of fever, instead of forbidding bleeding, is the most vehement call of the system for it. Nor is the absence of a crust on the crassamentum of the blood, a proof of the absence of great morbid diathesis, or a signal to lay aside the lancet. On the contrary, I shall show hereafter, that there are several appearances of the blood which indicate more morbid action in the blood-vessels than a sizy or inflammatory crust.