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Experiments. 1st. To show the earthy without the animal matter, burn a bone in a clear fire for about fifteen minutes, and it becomes white and brittle, because the gelatin, or animal matter of the bone, has been destroyed.

2d. To show the animal without the earthy matter of the bones, immerse a slender bone for a few days in a weak acid, (one part muriatic acid and six parts water,) and it can then be bent in any direction. In this experiment, the acid has removed the earthy matter, (carbonate and phosphate of lime,) yet the form of the bone is unchanged.

69. The bones are formed from the blood, and are subjected to several changes before they are perfected. At their early formative stage, they are cartilaginous. The vessels of the cartilage, at this period, convey only the lymph, or white portion of the blood; subsequently, they convey red blood. At this time, true ossification (the deposition of phosphate and carbonate of lime) commences at certain points, which are called the points of ossification.

70. Most of the bones are formed of several pieces, or centres of ossification. This is seen in the long bones which have their extremities separated from the body by a thin partition of cartilage. It is some time before these separate pieces are united to form one bone.

71. When the process of ossification is completed, there is still a constant change in the bones. They increase in bulk, and become less vascular, until middle age. In advanced life, the elevations upon their surface and near the extremities become more prominent, particularly in individuals accustomed to labor. As a person advances in years, the vitality diminishes, and in extreme old age, the earthy 31 substance predominates; consequently, the bones are extremely brittle.

How can the earthy matter of the bones be shown? The animal? 69. What is the appearance of the bones in their early formative stage? When does true ossification commence? 70. How are most of the bones formed? 71. What is said of the various changes of the bones after ossification?

72. The fibrous membrane that invests the bones is called per-i-os´te-um; that which covers the cartilages is called per-i-chon´dri-um. When this membrane invests the skull, it is called per-i-cra´ni-um.

Fig. 6.