This beautiful woman was born on St. Catherine's Day, in 1454, in one of the distinguished Venetian families. Her mother was the granddaughter of the Emperor of Trebizond, and her father of most noble descent.

James Lusignan, whom, as king of Cyprus, Caterina was afterwards to wed, had been driven from his home by the intrigues of the second wife of his father, Elena Paleologus, who, in order that her daughter might come to the throne, had secured James's appointment as Archbishop of Nicosia, where he lived a gay life, little suited to the office he held.

Many Venetian merchants frequented Nicosia; and there Andrea Cornaro, uncle of Caterina, became the intimate friend of the youthful archbishop. Happily for James, Queen Elena died before his father, who at once recalled his son to his side with the intention of securing the succession to him. But death claimed the old king before the proper steps had been taken; and Charlotte, the daughter of Elena, was proclaimed queen. James took the oath of allegiance, and was about to leave the island, when he was detained and confined in prison, and an attempt made to poison him.

But thanks to his friends and the Cypriotes, who preferred a king to a queen, he escaped and reached his bishopric, fully determined to dethrone his sister if possible. Genoa had favored Charlotte; and Andrea Cornaro was confident that on this account, if for no other reason, Venice would aid James to gain his rights,—such was the enmity between the two republics. Queen Charlotte was greatly alarmed by the escape of James. She knew not what to fear from his intrigues, and she was fully conscious of her unpopularity in Cyprus. She was betrothed to Louis, son of the Duke of Savoy, who had been selected by Queen Elena on account of the feebleness of his character, for the desire to rule absolutely was so powerful with her that she wished for no energetic son-in-law; and little as she could rely on him, Charlotte begged him to hasten to her assistance. Louis passed through Venice, and reached Cyprus before James had time to perfect a plan of action.

At Nicosia James felt himself to be in danger, and determined to fly; and as the Sultan was the titular ruler of Cyprus, James put himself under his superior at Alexandria. The beauty and charming manner of the young king of Cyprus, together with his sex,—a strong argument in his favor to the Oriental mind,—so influenced the Sultan that in the midst of his Mamelukes, in the great hall of the palace, he adopted James as his son, ordered him to be robed and crowned, and declared him King of Cyprus. It has been said, and repeated by a few chroniclers, that James signed a recantation of the Christian faith, and thus succeeded in his plans. Indeed, a document of this nature was sent to Pius II.; but it is believed by good authorities that this paper was a forgery perpetrated by the knights of Rhodes, who were greatly in favor of Queen Charlotte.

Be this as it may, James was twenty-two years old when the Sultan gave him ships and Mamelukes with which to conquer Cyprus. Very shortly he was master of the kingdom. Little resistance was made, and that was of a feeble sort. Louis returned to his father's court; and Charlotte went first to Rhodes, and then to Rome, to implore the aid of the Pontiff against her infidel brother and his allies. James now saw that his enemies—the Genoese, the Duke of Savoy, and the Pope—were far too powerful for him to struggle against them without aid, and the only bribe with which he could repay an ally was his kingdom. Marriage was his one means of salvation, and Cyprus was a dowry that could not fail to be acceptable. Several powers hinted at their readiness to form such an alliance with him; but Andrea Cornaro boldly asserted that Venice only could maintain his power, and proposed his niece, Caterina, as his wife.

It is said that by chance James had seen a miniature of Caterina, and had fallen in love with the sweet girl it represented; but the uncle skilfully pretended that the original of the picture was quite out of the reach of the king, and aroused him to a frenzy of passion. Then he told the truth,—that Caterina was his niece, and could only be won as Queen of Cyprus. At once James sent an embassy to demand her hand in marriage.

The Senate accepted in the name of Venice; and that Caterina might be the equal of her husband, they promised a dowry of a hundred thousand ducats, and to adopt her as a daughter of the Republic. The contract was signed by the Doge and by the ambassador of James, in 1468; and the Hall of the Great Council was the scene of the betrothal. The bride was conducted from the Palazzo Cornaro to the Ducal Palace by forty ladies of quality. She was received by the Doge and Senate and other officials. Mastachelli, as the representative of his master, placed a consecrated ring on her finger. The Doge gave her away to James Lusignan, and then with royal ceremony she was re-conducted to her father's house.

Thus far all was well; but, alas! some difficulties arose in the negotiations between her parent, Venice, and her husband, Cyprus. Four weary years rolled on, and still Caterina remained in Venice. She was treated as a queen, but she must many times have doubted if this pretence would become a reality.

Ferdinand of Naples was using every means in his power to persuade James to refuse Caterina and marry his daughter. James quarrelled with Andrea Cornaro; and finally Venice sent an ambassador to Cyprus to declare plainly that a rupture of the marriage contract would be revenged by the guardian of the queen, but that its fulfilment would assure the protection of Cyprus by the Republic. In 1471 James sent his representatives to bring Caterina to him.