As soon as Byron became of age in 1809, the two friends left England together to visit Greece, Portugal, Spain, and Turkey. The results of these travels were, Byron's first two cantos of "Childe Harold," and Hobhouse's "Journey across Albania, and other Provinces of Turkey in Europe and in Asia."

On their return to England, their intimacy did not cease. "Hobhouse," Byron was wont to say, "ever gets me out of difficulty;" and in his journal of 1814 he says, "Hobhouse has returned. He is my best friend, the most animated and most amusing, and one whose knowledge is very deep and extensive. Hobhouse told me ten thousand anecdotes of Napoleon, which must be true. Hobhouse is the most interesting of travelling companions, and really excellent."

Lord Byron wished him to be his best man when he married Miss Milbank at Seaham, and after his separation from her Hobhouse joined him in Switzerland. They travelled together through the Oberland, and visited all the scenes which inspired that magnificent poem entitled "Manfred." Thence they left for Italy, and visited it from North to South; from the Alps to Rome. The result of this journey was the fourth canto of "Childe Harold" from Byron, and from Hobhouse a volume of notes, which constitutes a work of very great merit. If such a companion was agreeable to Byron, Byron was not less so to Hobhouse, who deplores a journey he had made without the company of that friend, whose perspicacity of observation and ingenious remarks united in producing that liveliness and good-humor, which take away half the sting of fatigue, and soften the aspect of danger and of difficulties.

During his absence from England Byron always insisted that all matters relating to the settlement of his affairs should pass through the hands of Hobhouse, his "alter ego" when near or when absent. His highest testimony of regard and friendship for Hobhouse, however, is to be found in the dedication of the fourth canto of "Childe Harold," which was written in Italy in 1815, and which is as follows:—

Canto the Fourth.

To John Hobhouse, Esq., A.M., F.R.S., etc.

Venice, January 2, 1818.

My dear Hobhouse,—After an interval of eight years between the composition of the first and last cantos of Childe Harold, the conclusion of the poem is about to be submitted to the public. In parting with so old a friend, it is not extraordinary that I should recur to one still older and better,—to one who has beheld the birth and death of the other, and to whom I am far more indebted for the social advantages of an enlightened friendship, than—though not ungrateful—I can, or could be, to Childe Harold, for any public favor reflected through the poem on the poet,—to one whom I have known long and accompanied far, whom I have found wakeful over my sickness and kind in my sorrow, glad in my prosperity and firm in my adversity, true in counsel and trusty in peril,—to a friend often tried and never found wanting;—to yourself.

In so doing, I recur from fiction to truth; and in dedicating to you, in its complete or at least concluded state, a poetical work which is the longest, the most thoughtful and comprehensive of my compositions, I wish to do honor to myself by the record of many years' intimacy with a man of learning, of talent, of steadiness, and of honor. It is not for minds like ours to give or to receive flattery; yet the praises of sincerity have ever been permitted to the voice of friendship; and it is not for you, nor even for others, but to relieve a heart which has not elsewhere, or lately, been so much accustomed to the encounter of good-will as to withstand the shock firmly, that I thus attempt to commemorate your good qualities, or rather the advantages which I have derived from their exertion. Even the recurrence of the date of this letter, the anniversary of the most unfortunate day of my past existence,[25] but which can not poison my future while I retain the resource of your friendship, and of my own faculties, will henceforth have a more agreeable recollection for both, inasmuch as it will remind us of this my attempt to thank you for an indefatigable regard, such as few men have experienced, and no one could experience without thinking better of his species and of himself.

It has been our fortune to traverse together, at various periods, the countries of chivalry, history, and fable—Spain, Greece, Asia Minor, and Italy; and what Athens and Constantinople were to us a few years ago, Venice and Rome have been more recently. The poem also, or the pilgrim, or both, have accompanied me from first to last; and perhaps it may be a pardonable vanity which induces me to reflect with complacency on a composition which in some degree connects me with the spot where it was produced, and the objects it would fain describe; and however unworthy it may be deemed of those magical and memorable abodes, however short it may fall of our distant conceptions and immediate impressions, yet as a mark of respect for what is venerable, and of feeling for what is glorious, it has been to me a source of pleasure in the production, and I part with it with a kind of regret, which I hardly suspected that events could have left me for imaginary objects.