HYPOQUINIDOL
An examination of the advertising matter fails to show that R. W. Gardner makes any definite statement in regard to the nature or the composition of his Hypo-Quinidol. Certain statements made in the literature sound much as if the article might be some sort of a quinin hypophosphite preparation. But if this is true, its action would be the same as other salts of quinin and the extravagant claims made could not be substantiated. It is said to be a “non-toxic quinin.” It is safe to say that a quinin which will not produce the toxic symptoms—cinchonism—either is not absorbed in sufficient quantity or has been so changed that it no longer has the therapeutic properties of quinin. Altogether Hypo-Quinidol must be put down as a preparation the composition of which is kept secret and regarding which extravagant and highly improbable statements are made.—(From The Journal A. M. A., Jan. 10, 1914.)
IODONUCLEOID
An Iodin Product Under a Misleading Name
Information has been frequently asked concerning Iodonucleoid, a product not included in New and Nonofficial Remedies. The Association Laboratory after investigating this preparation reported as follows:
This preparation was at one time considered for inclusion with New and Nonofficial Remedies, and at that time was examined in this laboratory. The examination showed that iodonucleoid contains:
Phosphorus | 0.79 | per cent. |
Calcium | 0.43 | per cent. |
| (Equal to 0.6 per cent. CaO). | ||
Iodin | 24.2 | per cent. |
When 2 gm. was dissolved in tenth-normal potassium hydroxid volumetric solution and acetic acid added until faintly acid, an abundant, white, flocculent precipitate formed. This precipitate was collected, washed with water, transferred to a beaker, phenolphthalein added and tenth-normal potassium hydroxid volumetric solution run in until a pink color was produced. This required 15 c.c. of tenth-normal alkali. Subtracting from the 2 gm. of iodonucleoid the 24 per cent. iodin, leaves 1.52 gm.; this divided by the c.c. of alkali used indicates an equivalent weight of 1013.