“If the physician to whom such a patient comes for advice, instead of taking the wise course of seeking reliable information, were to take at their face value the statements of interested commercial manufacturers—if he were to administer this unknown and dangerous remedy, the effects of which he cannot predict—he would commit a breach of trust more culpable than the most vicious attempts of the nostrum-maker to mislead the physician and the public.”—(From the Journal A. M. A., Dec. 14, 1912.)
LYSOL-THE EVOLUTION OF A PROPRIETARY
Regarding certain proprietary preparations and their equivalents found in the pharmacopeias or other standard works of reference, it is often questioned whether the proprietary is the original and the official preparation the imitation, or vice versa. As a general proposition, medicinal compounds and preparations are not born but evolved, as in the case of epinephrin, in which the credit of discovery belongs to no one person, but to several.[108] So it is often the case that the proprietary and official preparations may be based one on the other, while both are usually based on some preparation which antedates them. This is well illustrated by the proprietary preparation Lysol, the practical equivalent of which—liquor cresolis compositus—is official in the United States Pharmacopeia. After the discovery of phenol (carbolic acid) and the recognition of its germicidal value, it was gradually learned that other phenolic compounds occurring in the crude distillates from tar and wood were more efficient and less poisonous than phenol (carbolic acid). When this was discovered, attempts of course were made to utilize these higher and more efficient phenols, which meant that their insolubility in water had to be overcome. In these attempts there were efforts to form new compounds as well as a search for simple solvents. While the first failed, because these compounds were less efficient than the phenol from which they were made, a simple solvent was found in soap. The first attempt to utilize the solvent power of soap gave creolin, a mixture of the so-called crude carbolic acid (really containing but little phenol and consisting largely of higher phenols along with inert hydrocarbons) with soap. This was followed in 1884 by Schenkel’s discovery that a portion of this “crude carbolic acid” could be made soluble in water by treatment with soap. Schenkel was refused a patent on the ground that any soap manufacturer should be permitted to add phenol to his soap, but in 1889 a patent for a cresol-soap solution was granted to Damann, who used cresol, a constituent of “crude carbolic acid.” The preparation was put on the market and has since been widely advertised under the proprietary name “Lysol.”[109] It is thus seen that Lysol is a good example of the way in which manufacturers appropriate the discoveries of others, develop them and turn them to proprietary use.
The ill-deserved patent protection for Lysol happily expired long ago and the product can now be made by anyone. In view of the non-descriptive character of the name “Lysol” and the danger in using such names in connection with potent and poisonous remedies, this cresol-soap solution has been admitted to pharmacopeias, not under the original name “Lysol,” but under descriptive names such as that in the United States Pharmacopeia—“liquor cresolis compositus.”—(From The Journal A. M. A., Dec. 14, 1912.)
THOMPSON’S MALTED FOOD COMPANY
And Its Blood, Nerve and Tissue Builder, “Hemo”
During the past eighteen months The Journal has received inquiries from physicians in various parts of the country asking for information regarding “Thompson’s Malted Food Company” of Waukesha, Wis., which for some time has been selling and trying to sell its stock to physicians and others. In reply The Journal called attention to the fallacy of any concern trying to induce people to purchase its stock on the ground that the Bromo-Seltzer company, the Postum Cereal company and others had been successful.
