The trade package recommends the use of Formosol “for cuts, wounds, ulcers, abscesses ...” This is a conflict with Rule 4. The Council held Formosol in conflict with Rules 4 and 6, and advised the manufacturers that Formosol is refused admission to New and Non­official Remedies until they submit evidence establishing the degree of antiseptic and germicidal efficiency, and justify the quotations listed above; or until these and any other existing conflicts with the Rules have been removed.

After submission of this report to The Formosol Chemical Company the Council authorized its publication.—(From Reports of Council on Pharmacy and Chemistry, 1917, p. 145.)


IODOLENE, A SOLUTION OF IODIN IN LIQUID PETROLATUM, INADMISSIBLE TO N. N. R.

Report of the Council on Pharmacy and Chemistry

The Council was asked to consider a solution of iodin in liquid petrolatum, said to be prepared from Gulf Coast petroleum by a special process. It was to be marketed as “Iodolen” provided the Council found the preparation admissible to New and Non­official Remedies. The preparation was claimed to contain over 1.5 per cent. free iodin. The following claims were made:

“It is less irritating in its use on the skin, or in wounds.” “Will kill pathogenic micro-organisms present.” “Is a suitable medium for cell proliferation.” “Will penetrate a useful distance into the walls of a wound.” “Facilitates an easier, less painful and better method of dressing wounds or ulcers.”

Examination in the American Medical Association Chemical Laboratory showed a submitted sample to contain 1.32 per cent. free iodin and to emit a strong odor of hydrogen sulphid. A specimen of liquid petrolatum, said to be composed chiefly of hydrocarbons of the naphthene series, after saturation with iodin at room temperature was found to contain 1.42 per cent. free iodin. Another specimen of liquid petrolatum, said to be composed chiefly of saturated hydrocarbons, after saturation at room temperature was found to contain 1.30 per cent. free iodin.

The preparation having been shown to be an unoriginal, simple solution of iodin in liquid petrolatum, the Council declared the name “Iodolene” unacceptable (Rule 8) and the therapeutic claims made for the preparation unwarranted (Rule 6).—(From Reports of Council on Pharmacy and Chemistry, 1917, p. 148.)