The Council declared NuTone inadmissible to New and Non­official Remedies because it is an irrational shotgun mixture advertised indirectly to the public with unwarranted therapeutic claims and a nondescriptive thera­peutically suggestive name.—(From Reports of Council on Pharmacy and Chemistry, 1917, p. 154.)

TRI-ARSENOLE, L. O. COMPOUND NO. 1 AND L. O. COMPOUND NO. 2

Report of the Council on Pharmacy and Chemistry

Tri-Arsenole.—According to the advertising of the Medical Supply Company of Atlanta, Ga., “Tri-Arsenole” is “Merco-Arseno-Benzo-Chloride,” and the claim is made:

“This compound is the result of many years’ research. The toxicity has been fully tested upon animals before using clinically, the latter having proven such complete success, we take pleasure in presenting it to the public ...”

“The manufacturers of TRI-ARSENOL, before placing it upon the market, tested it biologically.”

Tri-Arsenole is “recommended and suitable for the treatment of primary, secondary, tertiary and hereditary syphilis. It has also been found very useful in pellagra and malaria.” The preparation is supplied in ampules containing varying amounts of the dry substance. It is to be dissolved in water and is to be administered intravenously. In the advertising attention is called to the yellow color of Tri-Arsenole; this, and the style of package suggest that it is a preparation similar to salvarsan.

In reply to a request sent the Medical Supply Company for the quantitative composition and chemical formula of the compound “Merco-Arseno-Benzo-Chloride” and for the details of the biologic test by which its toxicity is claimed to have been determined and evidence for its efficiency, the following statement was received:

“Tri-Arsenole No. 1 equals to each Ampoule,gr.

Sodium chlorid

41⁄2

Hydrarg chlor.-cor.

 1⁄4

Arsenous acid

 1⁄4

Sodium benzoate

4

Hydrastin (resinoid)

2
Tri-Arsenole No. 2 equals to each Ampoule,

Sodium chlorid

4

Hydrarg chlor.-cor.

 1⁄2

Arsenous acid

 1⁄2

Sodium benzoate

4

Hydrastin (resinoid)

2
Tri-Arsenole No. 3 equals to each Ampoule,

Sodium chlorid

31⁄2

Hydrarg chlor.-cor.

 3⁄4

Arsenous acid

 3⁄4

Sodium benzoate

4

Hydrastin (resinoid)

2
Tri-Arsenole No. 4 equals to each Ampoule,

Sodium chlorid

3

Hydrarg chlor.-cor.

1

Arsenous acid

1

Sodium benzoate

4

Hydrastin (resinoid)

2