In consideration of the confusion which arises from the application of different names to an identical article, the rules of the Council provide that when an article which has been accepted for New and Nonofficial Remedies is admitted to the U. S. Pharmacopeia under another name, it will be retained, provided the official name is given prominence on the label and in the advertising of such article. Neither the label nor the advertising for Urotropin gives prominence to the pharmacopeial name as a synonym nor indeed does it bring out the fact that Urotropin is a brand of hexamethylenamine, U. S. P. Schering and Glatz, Inc., was advised that Urotropin could be retained in New and Nonofficial Remedies only on condition that the objections to the therapeutic recommendations were removed and on agreement that the U. S. P. name appear on the labels and circular matter. The firm did not offer to make the product eligible for continued recognition; accordingly the Council directed the omission of Urotropin because of conflict with Rule 6 (Unwarranted Therapeutic Claims) and with Rule 8 (Objectionable Names).—(From Reports of Council on Pharmacy and Chemistry, 1921, p 71.)
STYPTYSATE NOT ADMITTED TO N. N. R.
Report of the Council on Pharmacy and Chemistry
The Council has authorized publication of the following report, declaring Styptysate (Ernst Hischoff Co., Inc.) inadmissible to New and Nonofficial Remedies.
W. A. Puckner, Secretary.
Styptysate, according to the advertisement of Ernst Bischoff Co., Inc., New York, is “obtained by dialysis from Bursa Pastoris (Sheppard’s [sic!] Purse).” It is claimed to be “The Remedy For Hemorrhages,” to be “Superior to Ergot and Hydrastis,” “of particular advantage in Menorrhagia and Metrorrhagia” and to have been “found of great value in vesical hemorrhages and hemorrhages from mucous membranes in general.” The Styptysate label bears the synonym “Dialysate Herba Bursa Pastoris”; the statement that it contains “alcohol 11 per cent.” and that it is “made in Germany.” No other statement of the composition or strength of “Styptysate” is furnished nor is the name of the German manufacturer disclosed.
In an advertising circular entitled “Styptysate, a New Reliable Hemostatic,” it is declared that in recent years the plant, Shepherd’s Purse (Capsella bursa pastoris), “has been submitted to clinical tests in the form of a concentrated dialysate, known as Styptysate, by Loewy, Oppenheim, Krummacher and others, and that their reports coincide in regard to Styptysate as a hemostatic par excellence, particularly in uterine hemorrhages, even in cases where ergot and hydrastis had failed to produce satisfactory results.” The circular also reprints some “short clinical reports” without reference to their authorship; one ascribed to Krummacher and two ascribed to “B.H.M., Kansas City, Mo.,” and the following references: “A. Krummacher, M.D., Monthly Review for Obstetrics and Gynecology, Berlin, Vol. XLIX, 4, and Vol. LII.” “H. Oppenheim, M.D., Medical Clinic, Berlin, 1920, 35.”
Shepherd’s Purse is a weed common in the United States and in Europe. Like most other herbs, it has some reputation as a folk medicine. It is used by eclectics and homeopaths, being included in the Homeopathic Pharmacopeia of the United States. Shepherd’s Purse receives no consideration at the hands of the authors of standard works on materia medica, pharmacology or therapeutics.