[210] Apoth. Ztg., 1915, p. 247; Bull. soc. chem., 17 (1915), 401. “Studies of the decomposition of aspirin determined by titrametric methods and by conductivity measurements indicate that the reaction is exceedingly complex,” T. and H. Chem. Abs., 10, 591.

[211] “In the Matter of Aspirin. Answer to the warning circular of the Bayer Co. of June 1, 1917,” by Mr. Paul Bakewell, Monsanto Chemical Works.

[212] U. S. patent number 812,554—the novocain patent—declares that the salt melts at 156 C. Evidently based on this, the German Pharmacopoeia Remedia “Hoechst” and past editions of New and Non­official Remedies give this melting point. Two specimens of German made novocain obtained from our files, stated to be manufactured by Farbwerke-Hoechst vorm. Meister, Lucius and Bruening, Hoechst a.M. were found to melt, respectively, between 154 and 155 C. and between 153.5 and 154.5 C. when the melting point was determined according to the directions of the U. S. Pharmacopoeia, 9th revision. The various specimens examined at that time melted between 153 and 155 C. and it was decided to permit this range.

[213] Annual Reports of the Chem. Lab. of the A. M. A., 1915, p. 89.

[214] Warren, L. E.: Iodin Ointment, Am. J. Pharm., August, 1917, p. 339.

[215] Ibid., p. 90.

[216] Reports A. M. A. Chemical Laboratory, 1915, p. 106; Ibid., 1917, p. 87.

[217] Ibid., 1917, p. 87.

[I] From the Chemical Laboratory of the American Medical Association.

[J] The first article of this series dealt with the purity of acetyl­salicylic acid. Leech, P. N.: Examination of American-Made Acetylsalicylic Acid, J. Indust. & Engin. Chem., April, 1918, p. 288. “What’s in a Name?” ibid., p. 255. Acetylsalicylic Acid, or “What’s in a Name?” Editorial, J. A. M. A. 70:1097 (April 13) 1918.