Biological Molecules
Mr Bonhote continues: “As a further illustration of how widely spread these lines are throughout the mammalian and avian kingdoms, we may note the assumption of the brown head in the case of the Black-headed Gull (Larus ridibundus), which invariably follows each year on lines similar to those related in the case of the shoveler, and . . . the method by which, on the approach of winter, the stoat assumes his white dress, is (although the change is from brown to white) again conducted along precisely similar lines.” Mr Bonhote argues with great force that, as the process occurs in two animals so widely separated, the fundamental cause must be a deep-seated one. There can be no doubt that these pœcilomeres of Bonhote are connected with our biological molecules. Each of these pœcilomeres is the result of the development of one of these unit characters; each is to be regarded as the centre of activity, the sphere of influence of a biological molecule, or the portion of one, which controls the colouring of a definite region of the organism. In the case of creatures which display the same colour throughout, these molecules all give rise to the same kind of colouring; in the case of animals which display a variety of colours and markings the various molecules give origin to various colours. But we must bear in mind that the final colour to which each colour-producing molecule gives rise depends to some extent on circumstances other than the constitution of the molecule. Thus it is that the young in most organisms differ in colour and marking from the adults. On this also depends the phenomena of seasonal and sexual dimorphism. The same colour-producing molecule may give rise to one colour under one set of conditions and to a totally different colour under another set of conditions.
It is a significant fact that under abnormal conditions the feathers of birds tend to disappear precisely on those spots where the pœcilomeres of Bonhote occur.
Thus in a sickly cage bird the feathers frequently show a tendency to fall off on the following spots: crown of head, lores, jaws, head generally, rump, vent and thighs.
Many wild birds—as, for example, the cranes—display patches of naked skin on the head, and these are usually situated on pœcilomeres. Similarly, natural excessive developments of plumage tend to occur on the pœcilomeres, or, rather, the spots characterised by pœcilomeres—for example, the train of the peacock. Loral plumage, it is true, is seldom long, but is often of a peculiar nature.
Colour mutations tend to occur on the pœcilomeres. Thus it is that these pœcilomeres often form the distinctive characters and markings of allied species. This is precisely what we should expect if the pœcilomeres correspond to biological molecules and mutations are the result of the rearrangement of the constituent parts of these molecules.
Still more significant is the fact that the colour-markings in hybrids tend to follow pœcilomeres.
Bonhote has performed a large number of experiments in hybridising ducks. Some of his hybrids were produced from three pure ancestors, as, for example, the pintail, the spotbill, and the mallard; others from two ancestors. Some of these hybrids were crossed with other hybrids, and others with the parent forms, hence Bonhote secured a number of hybrids, each of which had a distinctive appearance; but all the variations appearing among the hybrids were found to start on one or more of the pœcilomeres.
Certain of the hybrids showed a resemblance to one or other of the parent species, others were unlike either parent, and resembled either no known species or species other than their parents.
When a hybrid shows a resemblance to a species other than that to which either parent belongs, it is said to exhibit the phenomenon of atavism or reversion,—the individual is supposed to have been “thrown back” to an ancestral form.