Discontinuous variations, or mutations, on the other hand, may be the result of a rearrangement of the atoms within the biological molecule. Upon what causes this rearrangement it would not be very profitable to speculate in the present state of our knowledge. To do this would be to inquire into the cause of a re-grouping of entities of the existence of which we are not certain! For aught we know there may be an intracellular struggle for nourishment among the various molecules and among the atoms which compose the molecules. If one molecule enjoys any special advantage over the others the result may be an unusual degree of development of the resulting unit character; in other words, the result will be a variation in the organism. This variation may prove favourable or unfavourable to its possessor.
Struggle for Nourishment
Certain phenomena seem to point to a struggle for nourishment between the germinal and the somatic portions of the egg, between the parts from which the sexual cells of the resulting organism are produced and those which give rise to the body of the organism. Each molecule may strive, so to speak, to increase at the expense of the others. Thus, great size in an organism is likely to be produced at the expense of the germinal cell-forming molecules. In other words, great size in an organism would be incompatible with excessive fecundity. This is what we observe in nature. On the other hand, poor development of bodily tissue, as in the case of intestinal parasites, would be correlated with great fecundity. Some organisms are mere sacs full of eggs.
Success in the struggle for nourishment of one molecule might be shared by the other molecules near to it, hence the phenomena of correlation.
It is thus conceivable that, in a brood consisting of several individuals, a particular molecule or set of molecules in one of the individuals may receive more than its share of nourishment, and this will result in the organs of that individual which spring from the well-nourished molecules being exceptionally well developed. Thus arises the phenomenon of differences between the members of a litter or brood.
Natural selection will tend to eliminate those individuals in which the resulting variation is an unfavourable one. If the environment is such, as in the case of an internal parasite, that the production of germ cells is the most necessary function of the organism, then those individuals in which the germ-forming molecules increase at the expense of the body-forming ones will tend to be preserved. This would cause the phenomenon which biologists term degeneration. The nourishment of the various biological molecules may possibly depend on their relative positions in the egg. Those in a favourable position will then tend to develop at the expense of the others. This will result in variation along definite lines. Each succeeding generation will tend to an increased development of that particular organ to which the favourably-situated molecule gives rise. This process may continue, as in the case of the horns of the Irish elk, until the development of that particular organ becomes so excessive as to be positively injurious; then natural selection will step in and eliminate the species. But before this happens, something may cause a rearrangement of the biological molecules in the fertilised egg, and thus a mutation may arise, which, so to speak, strikes out a new line.
Origin of Mutations
Finally, on this conception there may be some sort of connection between fluctuating variations and mutations. We can picture the fluctuating variations being piled up, one upon the other, until there results a rearrangement of the atoms in one or more of the biological molecules which, in turn, causes a mutation.
Occasionally this remodelling, as it were, of one biological molecule may affect certain of the other molecules, and thus lead to correlated mutations.