People of that time wondered what use girls would make of Latin and philosophy, but Miss Beecher's able management of the school and her womanly and scholarly attainments so filled them with admiration that they gladly put their daughters in her charge. Here also entered twelve year old Harriet, not only as a pupil, but a pupil teacher, that she might help her father in paying the expenses of his large family. The experience of Harriet in this school was of much use in after life. She had to master problems without any assistance from others, and in doing this, she became self-reliant.

About ten years after this, her father was called to become President of Lane Theological Seminary at Cincinnati, Ohio. Catherine and Harriet felt bound to go with him, to help him in the new field of work. The journey, made by stage-coach across the mountains, was very tiresome. They settled in Walnut Hills, a suburb of Cincinnati, where the sisters opened another school.

In 1836, Harriet married Calvin E. Stowe, professor of Biblical Criticism and Oriental Literature in the Lane Seminary. Mr. Stowe, together with other intelligent men in Ohio at that time, was much interested in the advancement of education in the common schools. In order to study the question and to purchase books for the Lane Seminary, Mr. Stowe was sent abroad. This happened shortly after his marriage.

During his absence Harriet lived in Cincinnati with her father and brother, writing short stories and essays for publication and assisting her brother, Henry Ward, who was then editing a small daily paper.

The question of slavery had become an exciting topic in Cincinnati. Being near the borderland of Kentucky, a slave state, this city naturally became the center of heated discussions. Many slaves who escaped sought refuge in Cincinnati, and people who were friendly to their cause assisted them to reach Canada, where they were safe from capture by their so called masters.

Among the students of Lane Seminary were both Northerners and Southerners, and many fierce debates as to the rights and wrongs of slavery were carried on in that institution. The feeling was very intense and excitement ran high. Dr. Bailey, an editor who attempted to carry on in his newspaper a fair discussion of the slavery question, had his presses broken and thrown into the river.

Mrs. Stowe took into her family, as servant, a colored girl from Kentucky. Though by the laws of Ohio this girl was free, having been brought into the state by her mistress and left there, yet it was rumored that some one had come to the city from over the border hunting for her, with the intention of taking her back into slavery. Mrs. Stowe and Henry Ward Beecher drove the poor girl by night twelve miles into the country and left her with an old friend until such time as the search for her should be given up. This incident served Mrs. Stowe as the basis of her description in Uncle Tom's Cabin of Eliza's escape from Tom Loker and Marks.

Houses of free colored people were burned and even Lane Seminary stood in danger from the mob. Mr. Stowe and his family slept with firearms at hand ready to defend themselves if necessary. When the trustees of the college forbade all discussion of the question of slavery, nearly all the students left the institution.

Then Mrs. Stowe opened her house to colored children and taught them. One boy in her school was claimed by a master in Kentucky, arrested and put up at auction. Mrs. Stowe raised sufficient money to buy him and gave it to his distracted mother, who thus saved him. Heart-rending incidents like this were continually brought to the attention of the Stowe family, until at last they felt unable to endure the situation. They decided to come North where Mr. Stowe accepted a position in Bowdoin College, Maine.