A new element entered into the life of Mary when a little more than ten years of age. In the month of February, 1775, her brother Charles was born to feed the hunger of her loving heart. From the first he was her charge. She nursed the weakly child with tender care, fostered his loving disposition, and as she could, trained his infant mind. Their childhood thus passed hand in hand, in accord with their future lives.

When Charles was about seven years old he entered Christ's Hospital. It was here he first formed the friendship of Coleridge, which proved so fruitful in after years. As time passed over the household the circumstances of the Lambs, never affluent, became more straitened. The elder son, John, seems to have cared chiefly for himself, and not to have been very reliable for contribution to the family support. In his fifteenth year Charles left the Blue Coat School to bear his share (which proved to be a large one) of the burden of the family life. He obtained a clerkship in the South Sea House, which in two years was exchanged for a better one in the East India House, Mary at the same time also adding to the slender means by dressmaking.

A few years passed, not altogether without brightness, though much dimmed by the growing imbecility of the father, and the sickness and helplessness of the mother. In 1795 her father was pensioned by his kind old master, and the family removed into lodgings in Little Queen Street. The following year proved to the Lambs a disastrous one indeed. First Charles himself, from some immediate cause not very clear, became the victim of the fatal heritage. Mrs. Gilchrist suggests that it was the first and only love of which he was able to dream that "took deep hold of him, conspiring with the cares and trials of home life." Charles was, from whatever cause, for six weeks confined in an asylum. Writing to Coleridge, with whom he had kept up a constant intercourse, he says: "In your absence the tide of melancholy rushed in, and did its worst mischief by overwhelming my reason." It was during his confinement that, in one of his lucid intervals, he wrote the following sonnet to his sister:—

If from my lips some angry accents fell,

Peevish complaint, or harsh reproof unkind,

'Twas the error of a sickly mind

And troubled thoughts, clouding the purer well,

And waters clear of reason; and for me

Let this my verse the poor atonement be—

My verse, which thou to praise wert ere inclined