WILLIAM SUMMERS, a child of five years and a half old was inoculated the same day with Baker, with matter taken from the nipples of one of the infected cows, at the farm alluded to in page 35. He became indisposed on the 6th day, vomited once, and felt the usual slight symptoms till the 8th day, when he appeared perfectly well. The progress of the pustule, formed by the infection of the virus was similar to that noticed in Case XVII., with this exception, its being free from the livid tint observed in that instance.

CASE XX.

From William Summers the disease was transfered to William Pead a boy of eight years old, who was inoculated March 28th. On the 6th day he complained of pain in the axilla, and on the 7th was affected with the common symptoms of a patient sickening with the Small-pox from inoculation, which did not terminate 'till the 3d day after the seizure. So perfect was the similarity to the variolous fever that I was induced to examine the skin, conceiving there might have been some eruptions, but none appeared. The efflorescent blush around the part punctured in the boy's arm was so truly characteristic of that which appears on variolous inoculation, that I have given a representation of it. The drawing was made when the pustule was beginning to die away, and the areola retiring from the centre. (See [Plate, No. 3].)

CASE XXI.

April 5th. Several children and adults were inoculated from the arm of William Pead. The greater part of them sickened on the 6th day, and were well on the 7th, but in three of the number a secondary indisposition arose in consequence of an extensive erysipelatous inflammation which appeared on the inoculated arms. It seemed to arise from the state of the pustule, which spread out, accompanied with some degree of pain, to about half the diameter of a six-pence. One of these patients was an infant of half a year old. By the application of mercurial ointment to the inflamed parts (a treatment recommended under similar circumstances in the inoculated Small-pox) the complaint subsided without giving much trouble.

HANNAH EXCELL an healthy girl of seven years old, and one of the patients above mentioned, received the infection from the insertion of the virus under the cuticle of the arm in three distinct points. The pustules which arose in consequence, so much resembled, on the 12th day, those appearing from the insertion of variolous matter, that an experienced Inoculator would scarcely have discovered a shade of difference at that period. Experience now tells me that almost the only variation which follows consists in the pustulous fluids remaining limpid nearly to the time of its total disappearance; and not, as in the direct Small-pox, becoming purulent.–(See [Plate, No. 4].)