THE HEAD OF A HORSE WHICH HAD BEEN SLAUGHTERED FOR GLANDERS.

1. The lymphatic gland enlarged, hard, and adherent firmly to the interior of the jaw-bone.

In the early stage it is difficult to pronounce positively upon a case of glanders. Ulceration of the nasal membrane would be confirmation of the worst doubt; but the ulceration may be situated so high up as to defy all our efforts to distinguish it. Yet running from the nose may be perceptible, and the gland may be fixed to the jaw. Both of these symptoms, although lawfully provoking our fears, are frequently attendant upon aggravated or upon prolonged colds. The only lawful test, in such cases, is the administration of three doses of solution of aloes, eight ounces to the dose—allowing three days to elapse between each. If the horse be glandered, before the last purgative has set the real nature of the malady will be apparent in the aggravation of the symptoms. If glanders be not present, a little careful nursing will generally remove all effect of the medicine.

The glanders is mostly ushered in by febrile disturbance. The appetite is bad, the coat stares, and the pulse is quickened. A mash or two, however, apparently sets all right, and the matter is forgotten. Soon afterward a slight discharge may issue from one nostril; but it is so very slight, it excites no alarm. One of the lymphatic glands, on the same side as the moist nostril, alters in character. It may remain loose and become morbidly sensitive. Usually, however, it grows adherent to the jaw, turns hard, insensitive, and, from being wholly imperceptible in the healthy animal, enlarges to about the size of half a chestnut.

THE PRIMARY DISCHARGE OF GLANDERS.
SIMPLY A SLIGHT WATERY DEFLUXION.

THE SECONDARY DISCHARGE. A THICK AND COPIOUS
BUT STILL TRANSPARENT EXCRETION, CONTAINING
PIECES AND THREADS OF MUCUS.

At a later period the discharge, retaining its clear appearance, becomes more consistent, and, to a slight degree, the hairs and parts over which it flows are incrusted. It subsequently adheres to the margin of the nostril, and then, in the transparent, albuminous fluid may be seen opaque threads of white mucus. This marks the second stage.